Gene Information

Name : fliI (NIDE2291)
Accession : YP_003797929.1
Strain : Candidatus Nitrospira defluvii
Genome accession: NC_014355
Putative virulence/resistance : Virulence
Product : ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2237351 - 2238658 bp
Length : 1308 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1646201, 17002279, 17012787, 17202259, 17967465, 18216858, 18216859, 8491729, 9231413, 9286988; Product type e : enzyme

DNA sequence :
GTGAAGCTTAGCGAACGCCTCGAACAAGTCGAACCCTTATCCGTCACGGGCCGGGTGGCCCAAGCCGTCGGGATCGTCAT
TGAAGCCTCGGGGCCGTTCACCTCTGTCGGAGAGGTCTGCGAGATCACCCGTGAGGGCGGCCATGGCGCCGTCATGGCAG
AAGTGGTCGGATTCCGCGAGGATCGTGTGCTGCTGATGCCGCTGGGTGAAATGCAGGGCATCGGCCCGGGCAGCCGTGTC
GTGATGAAAGGGCACGTGGCGTCGGTGCCGGTCGGACCGCAGATGTTGGGACGAATTTTCGACGGACTCGGGCACCCGCT
GGACGGCTTGCCGCCGCTACGCACCGATGTCCAGGTTCCGTTGTATGCGCCTCCGCTGAATCCGCTGCATCGCGCGAGAA
TTACCCAGCCGGTCGATCTGGGCATTCGGGCGATCAATGCCCTGTTGACCTGCGGCCAAGGCCAGAAAATCGGCGTGTTT
GCCGGATCCGGGGTGGGAAAAAGCGTCTTGTTGGGCATGATCAGCCGGTATACGCAGGCGGATGTCCGGGTGATCGCCCT
CGTCGGCGAGCGGGGACGTGAAGTCAAAGAGTTCCTGGAGCGCGACCTGACCCCGGAAGCAAGGGCCCGCTCCATTGTCG
TCGTCGCGACCTCGGATCAACCGCCGCTGGTGCGCATTCGCGGCGCCTTGGTGGCGACGGCCATCGCCGAATATTTTCGC
GATTGCGGCAAACATGTATTGCTGATGATGGATTCCCTTTCCCGCCTGGCCTATAGCCAGAGAGAAGTCGGGCTTGCCAT
CGGTGAACCTCCCACCACCAAAGGGTATACACCGTCCGTTTTTGCCGTGTTGCCGAAATTGCTGGAGCGGGTCGGACCGG
CACAGAGCGGGGGCAGCATTACCGGGCTCTACACCGTGCTGGTCGACGGCGACGACCTCAACGATCCGGTCGCGGATGCC
GTGCGCTCCATTCTCGACGGACATATTGTGCTTTCACGTGAACTGGCTGCGCGCAATCACTTTCCGGCCATCGATATCCT
GCAGAGTACCAGCCGGGTCATGCGGGACATTGTCACGCCGGCACACTATGCCGCGGGGCGGTTGGTCCTGGAACGCACGG
CGCTCTATCGGCGCTCTGAAGATCTCATCACGCTGGGCGCGTATAAGCCCGGCACGAGCAAGGATCTGGATAAAGCCGTC
TCCGCTCATGAGGGCATTACGGCGTTCCTGCGGCAGGAGACGAAGCAGTCCGTCGGGTTGTCGCAGTCCATCGATGCTTT
GCTGGCGCTGGCAGGAACCATTCAATGA

Protein sequence :
MKLSERLEQVEPLSVTGRVAQAVGIVIEASGPFTSVGEVCEITREGGHGAVMAEVVGFREDRVLLMPLGEMQGIGPGSRV
VMKGHVASVPVGPQMLGRIFDGLGHPLDGLPPLRTDVQVPLYAPPLNPLHRARITQPVDLGIRAINALLTCGQGQKIGVF
AGSGVGKSVLLGMISRYTQADVRVIALVGERGREVKEFLERDLTPEARARSIVVVATSDQPPLVRIRGALVATAIAEYFR
DCGKHVLLMMDSLSRLAYSQREVGLAIGEPPTTKGYTPSVFAVLPKLLERVGPAQSGGSITGLYTVLVDGDDLNDPVADA
VRSILDGHIVLSRELAARNHFPAIDILQSTSRVMRDIVTPAHYAAGRLVLERTALYRRSEDLITLGAYKPGTSKDLDKAV
SAHEGITAFLRQETKQSVGLSQSIDALLALAGTIQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-84 50
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-94 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-84 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-84 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-81 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-81 49
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 49
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 49
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-83 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-79 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-80 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-80 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-79 48
escN AAC31513.1 L0034 Virulence LEE Protein 2e-79 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-79 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-79 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-79 48
escN AAC38383.1 EscN Virulence LEE Protein 1e-79 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-77 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-80 47
escN AAK26715.1 EscN Virulence LEE Protein 5e-80 47
escN AAL57542.1 EscN Virulence LEE Protein 5e-80 47
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-79 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-80 47
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-80 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-80 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-67 44
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-76 44
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-75 44
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-76 44
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-77 44
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-75 44
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-69 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-73 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-75 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-78 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-74 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-74 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 6e-64 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-65 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-65 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-72 42
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 8e-73 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-62 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-63 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 7e-63 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-63 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-63 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 4e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_003797929.1 ATPase FliI VFG2331 Protein 1e-93 52
fliI YP_003797929.1 ATPase FliI VFG0048 Protein 4e-96 52
fliI YP_003797929.1 ATPase FliI VFG1254 Protein 2e-93 52
fliI YP_003797929.1 ATPase FliI VFG2499 Protein 7e-91 52
fliI YP_003797929.1 ATPase FliI VFG0192 Protein 7e-94 49
fliI YP_003797929.1 ATPase FliI VFG0390 Protein 4e-88 48
fliI YP_003797929.1 ATPase FliI VFG0812 Protein 1e-79 48
fliI YP_003797929.1 ATPase FliI VFG0730 Protein 7e-80 48
fliI YP_003797929.1 ATPase FliI VFG2144 Protein 2e-88 47
fliI YP_003797929.1 ATPase FliI VFG0515 Protein 6e-76 44
fliI YP_003797929.1 ATPase FliI VFG1778 Protein 5e-67 43
fliI YP_003797929.1 ATPase FliI VFG0555 Protein 3e-63 41