Gene Information

Name : macB (NIDE1083)
Accession : YP_003796769.1
Strain : Candidatus Nitrospira defluvii
Genome accession: NC_014355
Putative virulence/resistance : Resistance
Product : putative macrolide ABC transporter ATPase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 1056032 - 1056742 bp
Length : 711 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 11421269, 11988180, 12832048, 9640644, 9872322, 9873074; Product type e : enzyme

DNA sequence : 
ATGGCTCCGTTGATTGTTTGCGAAGACCTCTGGAAGATTTATCGTGTCGGCGACGTTGAGGTGCAGGCATTGCGCGGCAT
CAACCTCACCATCGATCGCGGTGAATTTGTGGCGGTCATGGGTACATCCGGATCGGGCAAGTCGACCCTGATGAATATTC
TCGGCTGCCTCGACCAGCCCACGCGTGGTCGATATGAGCTGGATGGTTTGGATGTGGCGACGGCAAAACCGGATCTCCTG
GCCGAGCTTCGCAACCGGCAGATCGGCTTCGTATTTCAAAGCTTCAATCTGATTCCCAGAACCAGCGCGTTGGAGAATGC
CCAATTGCCGCTGTTTTATCGAGGCCTTTCGATCAAGGAACAGCGAAAACAGGCTGCCGCAGCGTTGCAGCGAGTCGGGT
TGGCCGGTCGGGAGCAGCATTATCCCACGCAGCTCTCCGGAGGCCAGCAACAGCGTGTGGCCATTGCGCGGGCGCTGGTC
GGGGCCCCTTCGATTCTTTTTGCCGACGAACCGACAGGCAATCTGGATACGGCTTCGAGCCGGGAGATCATGAGTATTCT
CGAAGAACTCAACCGCCAAGATGGCATCACCATCATTCTGGTGACCCACGAATCCGATATCGCCGCCTATGCCTCACGCG
AACTGGTCATGAAAGATGGCCGGATCACCCAGGACGTGCGGCGGGCCCCGCATCTGACTGTCGTGCAGTAG

Protein sequence : 
MAPLIVCEDLWKIYRVGDVEVQALRGINLTIDRGEFVAVMGTSGSGKSTLMNILGCLDQPTRGRYELDGLDVATAKPDLL
AELRNRQIGFVFQSFNLIPRTSALENAQLPLFYRGLSIKEQRKQAAAALQRVGLAGREQHYPTQLSGGQQQRVAIARALV
GAPSILFADEPTGNLDTASSREIMSILEELNRQDGITIILVTHESDIAAYASRELVMKDGRITQDVRRAPHLTVVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 7e-36 45
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-37 43
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 2e-37 43
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-37 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
macB YP_003796769.1 putative macrolide ABC transporter ATPase NC_012469.1.7686878. Protein 3e-56 55
macB YP_003796769.1 putative macrolide ABC transporter ATPase NC_008702.1.4606598. Protein 6e-44 51
macB YP_003796769.1 putative macrolide ABC transporter ATPase CP001581.1.gene798.p Protein 1e-37 46
macB YP_003796769.1 putative macrolide ABC transporter ATPase CP001581.1.gene598.p Protein 7e-35 43
macB YP_003796769.1 putative macrolide ABC transporter ATPase NC_012469.1.7685735. Protein 7e-36 41