Gene Information

Name : clpC (BACI_c01070)
Accession : YP_003790030.1
Strain : Bacillus cereus CI
Genome accession: NC_014335
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 95002 - 97437 bp
Length : 2436 bp
Strand : +
Note : ATP-dependent Clp protease

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCAATTCGTATTGGGCATAA
CAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTGATTGCTCTTG
GATTAAGTCCAGAGAAGGTTCAAAAAGAAGTAGAAGCGTTAATCGGACGCGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCGCGTGCTAAAAAGGTTATTGAGCTGTCTATGGATGAAGCTCGTAAATTAGGTCATTCTTACGTTGGAACAGAACA
TATTTTACTTGGCTTAATCCGCGAAGGTGAAGGGGTAGCGGCACGCGTTTTAAATAACTTAGGTGTTAGCCTAAATAAGG
CAAGACAACAAGTATTGCAACTTCTTGGAAGTAATGAAGCAAGTTCAGGTCACCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGCTTAGCACGTGATTTAACAGTTGTTGCACGTGAAAATCGTTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACAAAAAACAATCCTGTATTAATCGGGGAGCCTGGTGTAG
GTAAAACGGCAATTGCGGAAGGATTAGCACAACAAATCGTAAATAATGAAGTTCCTGAAACTTTACGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACGAAATACCGTGGTGAATTTGAAGACCGTTTGAAGAAAGTAATGGA
TGAAATTCGCCAAGCGGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATCGGTGCAGGTGGAGCAGAAGGTG
CTATTGACGCATCGAATATTTTAAAACCATCTTTAGCTCGTGGGGAATTACAATGTATCGGGGCGACAACGTTAGATGAA
TATCGCAAATATATTGAAAAAGACGCAGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATTTTGAAAGGTTTACGCGATCGTTATGAGGCACATCACCGCGTATCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAGTTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGTTTACGCGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAACAACAAGGAAAAGAAAACTCAGAAGTGACAGTAGAAGATATTGCAAATGTT
GTTTCTACATGGACTCGTATCCCGGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCCATCCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCGAAAGCTGTTCGCCGTGCTAGAGCAGGATTGAAAG
ATCCGAAACGTCCGATTGGGTCATTTATTTTCTTAGGGCCAACAGGTGTAGGTAAAACGGAGCTAGCAAGAGCGTTAGCA
GAATCTATGTTCGGTGATGAAGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAGCATTCTACTTCTCGTTT
AGTTGGGTCTCCTCCAGGGTATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAGGTTCGCCGTAAGCCATATTCAG
TTGTCCTATTAGACGAAGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCGAAAGGGCGTACGGTTGATTTCCGCAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAGGCGTTAAA
ACGTAATAAGCATCTTGGATTTAACGTACAAGATGAGAGCCGCGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAAGCCTTCCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAGCAAGAAATTGAATTGCATTTAACAGAAGG
AGCAATTTCGGCTATTGCTGATAAAGGGTTTGACCGAGAGTACGGTGCTCGCCCGCTTCGTAGAGCGATTCAGAAACATG
TAGAAGATAGACTATCCGAAGAACTGTTAAAAGGTGCTATTGAGAAAGGGCAGAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCCGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003790030.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 77
clpC YP_003790030.1 negative regulator of genetic competence clpC/mecB VFG0080 Protein 5e-148 52