Gene Information

Name : pyk (BP951000_0535)
Accession : YP_003785037.1
Strain : Brachyspira pilosicoli 95/1000
Genome accession: NC_014330
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 594186 - 595619 bp
Length : 1434 bp
Strand : -
Note : -

DNA sequence :
ATGAGAAAAACAAAAATAATAGCAACTTTAGGACCTAGATGGTCTAATGAAGAAATGGTAAAAAAGATAATAGAGAATGG
CGCTAATGTATGCAGGCTTAATTTTTCATTTGGAAGCTATGATGAACATTTAGAGAGAATAAACATAATAAGAAAAGTTT
CTGATGAGTTGGGTAAACCTGTAGCTATATTAGCAGATTTGCAGGGACCTAAAATAAGAATAGGTAAGCTAAAAGAGAAT
ATCACTGTAAAAGAAGGCGACATTGTAAAATTAAGCGGACATAAAGAAACTAATGATGAAAGCATAATACCTACTACGCA
TGAAAACATTGCTCATGATGTAAAGAGCGGTTCATTGCTTTTGATAGCTGACGGTACTATACAGCTTATAGTGGAATCTA
GTGATGAGGCTTCAAAACTTGTTGTATGTAAGGTTATAACTGGAGGTACTATATTAAGCAGTAAGGGTATTAATTTGCCT
GGTGCTCATGTAACAACAGAGGTGCTAACAGAAAAAGATGTTAGTGATGCTTTATTTGCTGCTAAAAACGGTGCTAATTA
TTTGGGTATGAGTTTTGTAAGAAGGGCAGAAGATGTTATAAGACTTAGAAAGATATTAGATGATAATAATTTTCAGCATG
TTGGAATTGTGTCAAAAATAGAAAATACAGAATCATTAGAAAATTTGGAAAGTATAATAAAAGTGTCTGATGGTGTAATG
GTGGCAAGAGGAGACTTGGGAGTAGAGATACCATTTGGAGAGGTTCCTGTTTGGCAGAAGAAGATACTAAAAATGGCAAA
CGATATGGGTAAGATTACAATAATAGCTACCCAAATGCTTGAGAGTATGACAAAAAGCCCAGTGCCATCAAGGGCCGAGG
CTAGCGATGTTGCTAATGCTGTATTAGACGGTACTGATGTTGTAATGATGTCTGCTGAGACTGCTTCGGGAGATTATCCT
ATAGAGTCTGTTAAGGCTATGGTTTCTATAGTAGAGGCTGCTGAGAAATCTGTTAATAAAACTTCTCATGACAATATGAC
TTATTTAGACAGCGGAGTTAATGATGCTTTGGCTGATAGTGCTTCTTATTTATCATATAGTTTAGATAATAAGGCGATAA
TAGCTCTTTCAAGGTCTGGAAGAACAGTTAGAAATCTATCTAAAAAAAGACCAAAAACTCCTATAGTATTTATGTCTGCT
GATAGTAATCTTTGTAATGGTCTTGCTATATGTCATAATGTTTATACTATACATATGCCTGAAGATTTGAACTTTAGTGC
TGGTATTAACCATGGAGGCGAGATTAACATACTTGAAGATACTTTGGTAGAGCATAAATTAGCAGAACATGGAGATAGAA
TTATTGTAGTGAGCGGAAGTAAATGGCAGGGTAGGTGGCAAGAGAATAGTGTTCGTATAGTAGTTATGCACTAA

Protein sequence :
MRKTKIIATLGPRWSNEEMVKKIIENGANVCRLNFSFGSYDEHLERINIIRKVSDELGKPVAILADLQGPKIRIGKLKEN
ITVKEGDIVKLSGHKETNDESIIPTTHENIAHDVKSGSLLLIADGTIQLIVESSDEASKLVVCKVITGGTILSSKGINLP
GAHVTTEVLTEKDVSDALFAAKNGANYLGMSFVRRAEDVIRLRKILDDNNFQHVGIVSKIENTESLENLESIIKVSDGVM
VARGDLGVEIPFGEVPVWQKKILKMANDMGKITIIATQMLESMTKSPVPSRAEASDVANAVLDGTDVVMMSAETASGDYP
IESVKAMVSIVEAAEKSVNKTSHDNMTYLDSGVNDALADSASYLSYSLDNKAIIALSRSGRTVRNLSKKRPKTPIVFMSA
DSNLCNGLAICHNVYTIHMPEDLNFSAGINHGGEINILEDTLVEHKLAEHGDRIIVVSGSKWQGRWQENSVRIVVMH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-65 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-65 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-65 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-64 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_003785037.1 pyruvate kinase VFG0479 Protein 3e-65 43