Gene Information

Name : guaA (BP951000_2231)
Accession : YP_003786705.1
Strain : Brachyspira pilosicoli 95/1000
Genome accession: NC_014330
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase glutamine amidotransferase protein
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2452907 - 2454451 bp
Length : 1545 bp
Strand : +
Note : -

DNA sequence :
ATGCAAAACAATATTGATAAAGTTTTAATACTAGATTTCGGCTCTCAGTTTACACAACTTATTACAAGAAGAATAAGAGA
ATTGAATGTGTATTCAGAAATTCACCCATTTCATGTTTCAATAGATTTTATAAAAGAGTTTAATCCAAAGGCAATAATAC
TTTCAGGAGGCCCTTCAAGCGTATATGAAGAAGATGCTCCTAAAGTTGATAAGAAGTTATTTGAACTTGGTATACCAATA
CTAGGAATATGTTATGGTATGCAAATAATAGTTTATTCTATGGGCGGAAAAGTTGAAAGTGCGGATAAAAGAGAATATGG
AAAAGCTGAAATTGAAATTACTAATCATGAAAGCATATTTAAATCATTTGGTAAAAACAATATTGTGTGGATGAGTCATG
GCGACAGTATTAAATCTATTCCTGAAGGTTTTGAACTTATAGCTAAAACACCTAATACTGAACTTGCTGCTATAGAAAAT
AAACAAAAAAATATTTATGCTATACAGTTTCACCCTGAAGTAGTTCACACTGAAAACGGAATAAAGATAATAGAAAATTT
CTTATTTAATATTTGTAAATGTGAAAGAAATTGGAATATGGGTTCTTTTATAGAATATGAAATAAAAAGAATAAAAGAAA
CTGTAGGCGATAAAAATGTAATACTTGGGCTTTCTGGTGGGGTGGATTCTTCTGTTGCTGCAGTGCTCATAGAAAAAGCT
ATAGGAAAGCAATTAAAATGTATATTTGTTAACAATGGACTATTAAGAAAAGATGAAGATAAAAAGGTTGTTGAAGTATT
TAGAGATAATTTCAATATTGATTTAATTTATGTTGATGCTTCAAAGAGATTTTTAGATAAATTAGCAGGAGTTACTGACC
CTGAGCAAAAGAGAAAAATAATAGGTCATGAATTTGTAAGCGTATTTAATGATGAAGCTAAAAAGATAGAGAATGTAGGA
TTTTTAGCACAAGGCACGCTTTATCCTGATGTAATAGAGAGTGTATCTTTAAGAGGAAGTTCTGCTGTTATAAAAAGCCA
TCATAATGTAGGCGGACTTCCAAAGGACATGAAATTTGAACTTTTAGAGCCGTTTAGAGAATTATTTAAAGATGAAGTAA
GAGAGATTGGCTTAGAATTAAAGCTTCCAGAAGATATAGTTTACAGGCAGCCTTTCCCTGGTCCTGGGTTAGCAGTTAGA
ATACTTGGAGACATCACAGAAGAGAGAGTAAAAATACTTCAAGAGGCTGATGATATAGTTGTAAGCGAGATAAAAAAGGC
TGGTCTTTACAGAAAATTATGGCAGTCTTTTGCTATACTTCTTCCTGTAAAAAGTGTTGGTGTTATGGGAGATGGTCGTA
CTTATGAGCAGGTTTGTGCTGTAAGATGTGTTGAGAGTGTTGATGCTATGACAGCTGATTGGGCTAAGATTGATTATAAT
GTTTTGGGTATAATATCAAACAGAATAATAAATGAAGTAAAAGGTATTAACCGCGTTGTTTATGATATATCTTCAAAACC
GCCTGCTACTATAGAATGGGAATAA

Protein sequence :
MQNNIDKVLILDFGSQFTQLITRRIRELNVYSEIHPFHVSIDFIKEFNPKAIILSGGPSSVYEEDAPKVDKKLFELGIPI
LGICYGMQIIVYSMGGKVESADKREYGKAEIEITNHESIFKSFGKNNIVWMSHGDSIKSIPEGFELIAKTPNTELAAIEN
KQKNIYAIQFHPEVVHTENGIKIIENFLFNICKCERNWNMGSFIEYEIKRIKETVGDKNVILGLSGGVDSSVAAVLIEKA
IGKQLKCIFVNNGLLRKDEDKKVVEVFRDNFNIDLIYVDASKRFLDKLAGVTDPEQKRKIIGHEFVSVFNDEAKKIENVG
FLAQGTLYPDVIESVSLRGSSAVIKSHHNVGGLPKDMKFELLEPFRELFKDEVREIGLELKLPEDIVYRQPFPGPGLAVR
ILGDITEERVKILQEADDIVVSEIKKAGLYRKLWQSFAILLPVKSVGVMGDGRTYEQVCAVRCVESVDAMTADWAKIDYN
VLGIISNRIINEVKGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-150 58
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-150 58
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-150 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-125 50