Gene Information

Name : clpB (BP951000_2092)
Accession : YP_003786570.1
Strain : Brachyspira pilosicoli 95/1000
Genome accession: NC_014330
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2298280 - 2300859 bp
Length : 2580 bp
Strand : -
Note : -

DNA sequence :
ATGGATTATAATAAATATACAATAAAAGCCCAAGAGGCAGTAAATGAAGCTGCTAATATAGCTAATGGTGAAGACCATAA
TGAAATAAAAAGCGAGCATTTACTTCTTGCATTATTAAAACAAGAGGACGGACTTATTCAGCCTTTAGTAGAAAGAATAG
GCGTTCCTATAAATACGTTAATAGATAAAACTCAAAGATTAGTTGATGAAAACGTAAAGGTTACAGGTGAAAATGTGCAG
TTACATTTGTCCACTAATGCTGGTAAAGTTTTAGCAAAAGCAGAAAAAGAAGCTAGTGCTTTAAAAGACCAATATGTATC
AACAGAGCATATATTCTTAGCACTTGTTGAAGCTGACAACAAAGCAGGCGACATGCTTAGAAAAAGCGGAATAAGTAAAA
AAGAAGTTTTAAGTGCATTAAAAGATTTAAGAAAAGGTCAAAGCGTAAATAGCCAAGACCCAGAAGCAAAAATGCAGGCA
CTTGATAAATACTGCCGTGATTTAACAGCATTAGCAGAAGCAGAAAAAATTGACCCTGTTATAGGACGTGATGAAGAGAT
AAGACGTGTTATGCAGGTGTTGTCAAGAAGAACAAAAAATAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAGACTG
CTATTGTTGAAGGACTTGCAAGAAGAATAGTTTCTCAAGATGTACCTGAGGGACTTAAAGATAAAAGGCTATTAGCTTTA
GATTTAGGAGCATTAGTAGCTGGTGCAAAATTCAGAGGAGAGTTTGAAGAGAGACTAAAAGCTGTTATCACAGAGATAGA
AAAATCTGAAGGAAGCATTATATTATTTATAGATGAGCTTCACACACTTGTAGGAGCTGGTGCTACAGAGGGAGCAATGG
ACGCTTCTAACCTATTAAAACCTGCATTAGCAAGAGGCGAATTAAGAGCAATAGGTGCTACTACTTTAGATGAATATAGA
AAATATATTGAAAAAGATAAAGCACTTGAGAGAAGATTCCAACAAGTTTATTGTAAAGAGCCTAGTGTTGAAGATACTAT
TTCAATATTAAGAGGCTTAAAAGATAAATACGAAGTTCATCATGGTGTTAGAATAAAAGACGATGCATTAGTTGCTGCTG
CTGTTTTATCTAACAGGTATATAACTAACAGATTCTTACCTGATAAAGCTATTGACTTGGTAGATGAAGCTGCAAGCCAA
TTAAAAATAGAGATAGACAGTCAGCCTACTGAACTTGATAAAATTGAAAGAAAGATTTTACAGCTTAATATAGAAAAACA
AGCTCTTTCAAAAGAAAATGATGCAGCATCTAAAGAGAGATTAGAAAAACTTGAAAAAGAATTATCTGAACTTTCTGAAG
AACGCAATGCTATGAAACTTCAATGGGATAATGAAAAAGGAAGAATTGAAGAGACTAGAAAATTAAAAGAAGAACTTGAA
GCTTTAAATATAAAAGAGACTCAATATACAAGAGAAGGTAATTTAGCAAAGGCTGCTGAAATAAAATATGGTAAAATACC
AGAATTACAGAAAAAATTAGAAGAAGCAACTAAAGCTATGGAAGAAGCTAAAAACTCTGACAAGAAAGGTCTTTTAAGAG
AAGAGATTTCTGAAGATGATATAGCTAGAGTAATATCTGTATGGACTGGAATACCTGTAAGTAAAATGCTTACAAGCGAA
AAACAAAAATACTTACAGCTTGAAGAAGTATTACATAAGAGAGTTGTAGGACAAGATGAAGCAATCACTTCAGTTGCTGA
TGCCATAAGAAGAAACAGAGCAGGACTTTCTGATGAAAATAAACCGCTTGGAAGTTTCTTATTTATAGGACCTACTGGAG
TTGGTAAAACAGAGCTTGCTAAAACACTTGCTGATTTCTTGTTTAGCGATGAAAAAGCTTTAACAAGAATTGATATGAGT
GAATATATGGAGAAGTTTTCTGTTACTAGACTTATAGGAGCTCCTCCTGGATATGTTGGTTATGATGAAGGTGGACAATT
AACAGAAGCAGTTAGAAGAAGACCTTATTCTGTTATACTATTTGATGAGATAGAAAAAGCTCACCCTGATGTATTTAATG
TTTTACTTCAGGTATTAGATGATGGAAGGCTTACTGACGGACAAGGAAGAATAGTAGATTTCAAAAATGCTATTATCATA
ATGACAAGTAATTTAGGTTCTGACCTTATTCTTGAAGCTAATGATACTAATGATATCAAAGAAAAAATTCAAGAGTTACT
AAAAATGTCATTTAGACCAGAGTTCTTAAACAGAATAGATGAGATAATAACATTTACTAGACTTGACAAAAAATACATTG
CTGAGATAGTAAGAAATCAAATAGCAAGAGTTGCTAACAGACTTAAAGATAGAAGAATAACTTTAGATGTAAGCGATGAA
GCTATAGACTATATTGCTGATATTGGTTATGACCCTCAGTTTGGAGCAAGACCATTAAAAAGAGCAATACAGAATTATAT
AGAAAACCCACTAGCTAAAGAAATGTTAGCAGGAAAATATTTAGAAGGAGATACTATAAAGGTAAAAAAATCAGGAGACG
GTTTGGTTTTTGAAAAATAA

Protein sequence :
MDYNKYTIKAQEAVNEAANIANGEDHNEIKSEHLLLALLKQEDGLIQPLVERIGVPINTLIDKTQRLVDENVKVTGENVQ
LHLSTNAGKVLAKAEKEASALKDQYVSTEHIFLALVEADNKAGDMLRKSGISKKEVLSALKDLRKGQSVNSQDPEAKMQA
LDKYCRDLTALAEAEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSQDVPEGLKDKRLLAL
DLGALVAGAKFRGEFEERLKAVITEIEKSEGSIILFIDELHTLVGAGATEGAMDASNLLKPALARGELRAIGATTLDEYR
KYIEKDKALERRFQQVYCKEPSVEDTISILRGLKDKYEVHHGVRIKDDALVAAAVLSNRYITNRFLPDKAIDLVDEAASQ
LKIEIDSQPTELDKIERKILQLNIEKQALSKENDAASKERLEKLEKELSELSEERNAMKLQWDNEKGRIEETRKLKEELE
ALNIKETQYTREGNLAKAAEIKYGKIPELQKKLEEATKAMEEAKNSDKKGLLREEISEDDIARVISVWTGIPVSKMLTSE
KQKYLQLEEVLHKRVVGQDEAITSVADAIRRNRAGLSDENKPLGSFLFIGPTGVGKTELAKTLADFLFSDEKALTRIDMS
EYMEKFSVTRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNAIII
MTSNLGSDLILEANDTNDIKEKIQELLKMSFRPEFLNRIDEIITFTRLDKKYIAEIVRNQIARVANRLKDRRITLDVSDE
AIDYIADIGYDPQFGARPLKRAIQNYIENPLAKEMLAGKYLEGDTIKVKKSGDGLVFEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-98 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003786570.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 2e-105 42