Gene Information

Name : fliI (BP951000_2076)
Accession : YP_003786555.1
Strain : Brachyspira pilosicoli 95/1000
Genome accession: NC_014330
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2279842 - 2281311 bp
Length : 1470 bp
Strand : +
Note : -

DNA sequence :
ATGTTTGAAGGCGGAAAAATAGAGGGTGAGAGAGAGCATTCTTTTAGAGAGATACATGACTCTTTTGACAAATACAGAAA
GGTTGTTGATGATGTTGCAATGCTCAAGTTTTGCGGTAAGGTAAAAGAGGTTATAGGTTCTCTTGTTGTGAGTGAAGGTC
CTTTTGCAAAGCTTGGAGATATTTGCCGTATATACAAAAATGATGATACATATATAGATGCTGAAGTTATAGGGTTTAGA
AATCAAGATGTTTTACTTTCTACTTACGGAAGTGTAAACGGTATTACTTTTGGAAATATGGTTTATTCTTTTGATAAGCC
TTTATCTATTATTTGTTCTGAGAAGATTTTAGGTACTGTATTAAATGGTATGGGTAAGCCTTTAAGCGGCGGCGGACATA
AATTTTATGAAACTCCTATACCTATAAATCATACTTCTGTAAATCCATTAAATAGACCAAGAATTAAAAAGAATATACAA
ACAGGTGTACGTGCTATAGACGGGCTTCTTACAGTTGGTAAGGGGCAGCGTATGGCTATAATGAGCGGTACGGGTGTTGG
TAAGTCTACTCTTTTATCTATGATAGCTAGAAACACTAATGCTGATGTTAATGTTATTGCATTGATTGGTGAGAGAAGAA
GAGAGGTATTAGATTTTATAGAAAGAGACCTTGGAGAAGAGGGGTTAAAAAGAAGTGTAGTTGTTGTTGCTACTAGCGAT
GATGCTCCACTTTTAAGAGTACGTGCTGCATATACTGCTACTACAATAGCCGAATATTTTAGAGACCAAGGCAAAGATGT
TATGTTTATGGTGGACTCTGTAACTCGTTTTGCTTTAGCTCAAAGAGAGATAGGGCTTTCTAGAGGTGAGCCTCCTACTA
CAAGAGGATATACTCCTAGTGTTTTTTCAGAATTAGCACAATTATTAGAGAGAACTGGTACTTCTTCAAAAGGCACAATT
ACAGCTTTCTACAATGTATTGGTTGAAGGTGATGATTTGGACGAGCCTATTACTGATGCTGTGAGAGGTATATTAGACGG
ACACATTGTTTTATCTAGAGATTTAGCTAATAGAGGACATTTCCCTGCTATTGATATAAATAAAAGCATATCTAGGATTA
TGAATGAAGTTGTTTCTAATATGCATAAAAAAGCTGCTAGAGAGTTTTTGAAAATGAGTGCTGATTATAATGAAGTTAAA
GAGCTTATTATGATTGGCGGTTATGCTAAGGGAAGTATGCCTGAAGTTGATAGGGCTATAGAATATAAACCTTTGATGGA
TAGGTATTTACAGCAGGATATGTATGAGCTTTCTAGTTTTGCAGACAGTAAAGAAAATCTGCTTTCTATGTTTTATTCTA
AAAATGAAATAGAAGAGGATTTACTTAATAATGGCGATGTAAAAAGTGCAAATGACTATAAAGAAATTTCCGATAATGTT
AAACAGGAAGATAGTGTTGTAATATTATAA

Protein sequence :
MFEGGKIEGEREHSFREIHDSFDKYRKVVDDVAMLKFCGKVKEVIGSLVVSEGPFAKLGDICRIYKNDDTYIDAEVIGFR
NQDVLLSTYGSVNGITFGNMVYSFDKPLSIICSEKILGTVLNGMGKPLSGGGHKFYETPIPINHTSVNPLNRPRIKKNIQ
TGVRAIDGLLTVGKGQRMAIMSGTGVGKSTLLSMIARNTNADVNVIALIGERRREVLDFIERDLGEEGLKRSVVVVATSD
DAPLLRVRAAYTATTIAEYFRDQGKDVMFMVDSVTRFALAQREIGLSRGEPPTTRGYTPSVFSELAQLLERTGTSSKGTI
TAFYNVLVEGDDLDEPITDAVRGILDGHIVLSRDLANRGHFPAIDINKSISRIMNEVVSNMHKKAAREFLKMSADYNEVK
ELIMIGGYAKGSMPEVDRAIEYKPLMDRYLQQDMYELSSFADSKENLLSMFYSKNEIEEDLLNNGDVKSANDYKEISDNV
KQEDSVVIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-89 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-90 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-90 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-91 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-90 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-91 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-91 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-91 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-87 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-87 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-80 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-80 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-75 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-75 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-75 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-75 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-75 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-80 45
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-77 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-80 44
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-81 44
escN AAC31513.1 L0034 Virulence LEE Protein 3e-80 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-80 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-80 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-80 43
escN AAC38383.1 EscN Virulence LEE Protein 4e-80 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-84 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 9e-80 42
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-80 42
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-79 42
escN AAK26715.1 EscN Virulence LEE Protein 7e-79 42
escN AAL57542.1 EscN Virulence LEE Protein 7e-79 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-79 42
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-73 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-74 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-76 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-76 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 9e-77 42
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-76 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-75 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG2144 Protein 1e-94 49
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0390 Protein 1e-90 48
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG1254 Protein 3e-90 48
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0192 Protein 3e-92 47
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG2499 Protein 5e-88 46
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG2331 Protein 2e-84 45
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0048 Protein 1e-88 45
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0515 Protein 3e-75 45
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0812 Protein 2e-80 43
fliI YP_003786555.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0730 Protein 3e-80 43