Gene Information

Name : mtrA (cpfrc_00518)
Accession : YP_003782918.1
Strain : Corynebacterium pseudotuberculosis FRC41
Genome accession: NC_014329
Putative virulence/resistance : Virulence
Product : two-component system transcriptional regulatory protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 532676 - 533353 bp
Length : 678 bp
Strand : +
Note : Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence :
ATGCCCCAGAAGATTCTTGTCGTTGATGATGATCCAGCCATCTCTGAGATGCTGACAATCGTGCTGGAAGCTGAAGGTTT
TAATACCGTAGCTGTCACCGATGGTGCCTTAGCAGTAGAAACCTTTAATCGAGAAGAACCGGATCTTGTTCTTCTGGATC
TTATGCTTCCAGGTATGAACGGTATCGATATTTGCCGTTTGATCCGTCAGAACTCGACAGTGCCTATAGTGATGCTCACA
GCTAAAACAGACACCGTTGACGTGGTGTTAGGGCTGGAAACGGGGGCGGATGATTACATCACTAAGCCTTTCAAGCCCAA
GGAACTCATTGCGCGGCTGCGGGCGCGGCTGCGCCGTACAGATGACGCACCCGCGGATGTCATCGAGATCAGCGATCTTG
CCATCGACGTCCCCGGCCATGTGGTCAGCCGCGGGCGAGAGGTTATCCAGCTCACCCCGTTGGAGTTTGATTTGCTTCTT
GAGCTAGCAAGTAAGCCCGGCCAGGTATTTACTCGGGAAGAATTACTGCAAAAGGTATGGGGATACCGGAACGCGTCGGA
TACCCGATTAGTCAATGTCCACGTGCAGCGGTTGCGTGCAAAAATTGAGAAGGATCCGGAGAACCCCCAGATCGTGCTCA
CTGTCCGAGGCGTCGGATACAAGACCGGGCAGGAGTAA

Protein sequence :
MPQKILVVDDDPAISEMLTIVLEAEGFNTVAVTDGALAVETFNREEPDLVLLDLMLPGMNGIDICRLIRQNSTVPIVMLT
AKTDTVDVVLGLETGADDYITKPFKPKELIARLRARLRRTDDAPADVIEISDLAIDVPGHVVSRGREVIQLTPLEFDLLL
ELASKPGQVFTREELLQKVWGYRNASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 6e-33 44
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 1e-32 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mtrA YP_003782918.1 two-component system transcriptional regulatory protein AE000516.2.gene3505. Protein 2e-65 72
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_002952.2859905.p0 Protein 5e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_007793.3914279.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_002745.1124361.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_009782.5559369.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_002951.3237708.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_007622.3794472.p0 Protein 5e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_002758.1121668.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_003923.1003749.p0 Protein 4e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_009641.5332272.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_013450.8614421.p0 Protein 6e-40 49
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_012469.1.7685629. Protein 5e-39 47
mtrA YP_003782918.1 two-component system transcriptional regulatory protein HE999704.1.gene2815. Protein 2e-36 46
mtrA YP_003782918.1 two-component system transcriptional regulatory protein NC_012469.1.7686381. Protein 7e-35 43
mtrA YP_003782918.1 two-component system transcriptional regulatory protein CP000675.2.gene1535. Protein 4e-30 42
mtrA YP_003782918.1 two-component system transcriptional regulatory protein HE999704.1.gene1528. Protein 3e-31 42
mtrA YP_003782918.1 two-component system transcriptional regulatory protein AE016830.1.gene1681. Protein 7e-34 41
mtrA YP_003782918.1 two-component system transcriptional regulatory protein BAC0125 Protein 4e-26 41
mtrA YP_003782918.1 two-component system transcriptional regulatory protein CP001918.1.gene3444. Protein 2e-29 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mtrA YP_003782918.1 two-component system transcriptional regulatory protein VFG1563 Protein 3e-33 44
mtrA YP_003782918.1 two-component system transcriptional regulatory protein VFG1702 Protein 4e-33 44
mtrA YP_003782918.1 two-component system transcriptional regulatory protein VFG1390 Protein 4e-27 42