Gene Information

Name : ureC (cpfrc_01925)
Accession : YP_003784325.1
Strain : Corynebacterium pseudotuberculosis FRC41
Genome accession: NC_014329
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2110336 - 2112045 bp
Length : 1710 bp
Strand : -
Note : Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGTCTTTTGAAATGAGTCGGCGTCAGTATGCAGAGCTGAATGGTCCGACCACCGGCGACGGAATCCGTTTGGCTGATAC
AGAGCTCATTGCCGTTGTTGAAAAGGATCTTACTCAGTACGGCGACGAGGTCTCCTTCGGCGGCGGAAAAGTTATCCGCG
ACGGCATGGGTCAAAACTCGCGCGTCGAGGCAGATCAGGTCCCGGACCTGGTTATCACGAACACCATTATCGTGGACTAC
ACCGGTATTTACTCTGCTGATATTGCTGTGAAAGACGGCAAGATCATGAAGATCGGTAAAGCGGGCAACCCCGATATTAT
GGACAACATCGACATCATCGTCGGTGTGGGTACGGAAGTTATTGGTGGCGAAGGCAAGATTGTCACTGCTGGCGCTATTG
ATACGCACATCCACTTTATTTCCCCGGAACAGGTGGAAGCTGCGCTGGACAACGGTACAACCACCCTTATCGGTGGCGGA
ACTGGCCCGGTTGATTCCACCAACGCTACTACCGTTACCGCAGGTGCTGCCAACATCACCAAGATGATTGAGGCTTCCCG
CGACTTCTCCGTGAACGTCGGTTTCTTGGGTAAGGGACACGCCTCAAACCCTGAGCGTCTGCGTGAGCAGATTCGAGCAG
GCGCTATCGGCCTGAAGATTCACGAGGACTGGGGTGCTACCGCTAACACCATCGACAACGCACTGACTGTTGCGGATGAG
ATGGACGTTCAGGTTGCCATCCACACCGATACCCTCAACGAGGGCGGTTTCGCGGACAACACCATTGCGGCTTTCAAAGA
TCGCGTTATCCACACCTTCCACACTGAAGGCGCTGGCGGCGGACATGCCCCGGATATTCTGAAGGTAGCTGGTCTGCCTA
ACGTTCTTCCTGCATCCACCAACCCAACGCTTCCGTTTACCGTGAACACGATGGATGAGCACCTTGACATGATCATGGTG
TGCCACCATCTCAATGCTGATCTTCCCGAGGATATTGCGTTTGCTGATTCGCGTATTCGTAAGGAAACCATTGCGGCAGA
AGATGTTCTGCACGATATGGGCGTCTTGGCAATCACTTCTTCTGACTCCCAAGCAATGGGCCGAGTTGGCGAGGTTGTCC
TGCGCACATGGCAGGTTGCTCACCGCATGAAGCAGCAGCGTGGCCCGCTTGAGGGCGATACCGTTAACAACGACAACGAG
CGCATTAAGCGTTACATCGCTAAGTACACCATCAACCCGGCTATTGCCGCTGGCGTCGCAGATACCATTGGTTCTGTTGA
AGAAGGAAAGCTGGCTGACCTGGTTGTTTGGGACCCTGCTTACTTTGGCGTGAAGCCAAGCATCGTGCTCAAGTCCGGTA
TCATCGCGCGCTCCATCATGGGTGATGCCAATGCCTCGATCCCGACTCCACAGCCACGTACTATGCGCTACTCCTTTGGC
GCTCGCGGCGCAGCTGCCGGTCGTACCTCTGTTACCTTCCTTCCCACAGCAGCTTTTGAGGCTGGCATACCTGAGAAGCT
GGGGATTGATCGTAAGTTTGTTGAGGCAAAGAACATGCGCGAGATCTCTAAAGCTGATCTGAAGTACAACAACGCAACGC
CAGATATCAAGGTTGATCCAGAGACCTATGAGCTGACGGTTGATGGAAAGAAGGTTACTTCTGAGGCTGCTACAGAACTG
CCGATGACTCAGCGTTACTTCCTGTTCTAG

Protein sequence :
MSFEMSRRQYAELNGPTTGDGIRLADTELIAVVEKDLTQYGDEVSFGGGKVIRDGMGQNSRVEADQVPDLVITNTIIVDY
TGIYSADIAVKDGKIMKIGKAGNPDIMDNIDIIVGVGTEVIGGEGKIVTAGAIDTHIHFISPEQVEAALDNGTTTLIGGG
TGPVDSTNATTVTAGAANITKMIEASRDFSVNVGFLGKGHASNPERLREQIRAGAIGLKIHEDWGATANTIDNALTVADE
MDVQVAIHTDTLNEGGFADNTIAAFKDRVIHTFHTEGAGGGHAPDILKVAGLPNVLPASTNPTLPFTVNTMDEHLDMIMV
CHHLNADLPEDIAFADSRIRKETIAAEDVLHDMGVLAITSSDSQAMGRVGEVVLRTWQVAHRMKQQRGPLEGDTVNNDNE
RIKRYIAKYTINPAIAAGVADTIGSVEEGKLADLVVWDPAYFGVKPSIVLKSGIIARSIMGDANASIPTPQPRTMRYSFG
ARGAAAGRTSVTFLPTAAFEAGIPEKLGIDRKFVEAKNMREISKADLKYNNATPDIKVDPETYELTVDGKKVTSEAATEL
PMTQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 100
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 100
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 0.0 100
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 100
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-160 63
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-160 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_003784325.1 urease subunit alpha VFG0270 Protein 1e-141 59