Gene Information

Name : clpB1 (cpfrc_01876)
Accession : YP_003784276.1
Strain : Corynebacterium pseudotuberculosis FRC41
Genome accession: NC_014329
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.21.92
Position : 2053289 - 2055838 bp
Length : 2550 bp
Strand : -
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATTCATTTAACCCAACAACTAAAACTCAGGAGGCCTTGCAAGTTGCACTGCAGCAGGCGTCTTCCTTAGGAAACCC
AGATATTCGGCCAGCACATTTACTTGCGGCGATCTTAGGCCAGGAGGACGGCATCGCCGTGCCCGTCTTGCGCGCTACGG
GCGTAGACCCACAGGTGGTGGCCAAGGAGGCCAATGCACTTGTAGCGGGGTATCCCAAGGCTGAGGGGTCTGGCATGGCC
AACCCCAACTTTAACCGCGATGCTCTCAACGCTCTGACCGCTGCGCAAGAGCTGGCTGGTGAATTAGGTGATGAGTACGT
ATCTACTGAGGTGCTACTCGCCGCGATTGCTCGGGGTAAGTCCGATGCTGCGGAGTTACTGACCAAGCGAGGCGCTACGT
ATGACGTGATTAAGGGAGTGTTCCCCTCTGTGCGAGGAAGCAAGAAGGTGACTAGTCAGGATCCGGAAGGCCAGTTCCAA
GCTCTGGAGAAGTATTCCACCGACCTTACGGCTCGTGCTCGTGAGGGAAAGATTGATCCCGTTATCGGGCGTGACTCGGA
GATTCGGCGTGTGGTTCAGGTGCTCAGCCGTCGCACTAAGAATAACCCCGTTCTTATTGGTGAGCCTGGCGTGGGTAAGA
CCGCGATCGTAGAAGGCCTGGCTCGCAGGATTGTTGCCGGCGATGTTCCGGAGTCGCTGAAGGGGAAGACCCTTATTAGC
CTTGATCTTGGATCGATGGTCGCTGGCGCCAAGTACCGTGGCGAGTTTGAGGAACGCCTCAAGGCTGTGCTTGATGAGAT
CAAGTCGGCAGAGGGCGAGATCATTACTTTTATTGATGAGCTGCACACCATTGTTGGTGCAGGAGCTACGGGCGATTCCG
CTATGGACGCCGGCAATATGATCAAGCCACTGCTGGCTCGTGGCGAGCTACGCCTAGTGGGTGCCACTACTCTGGATGAA
TACCGCAAGTACATCGAGAAAGATGCGGCCTTGGAACGCCGTTTCCAGCAGGTCTTTGTGGGCGAACCCTCTGTAGAAGA
CGCTATCGGTATTCTGCGCGGCCTTAAAGAGCGCTACGAGGTGCATCATGGTGTGCGTATTCAGGATTCCGCATTGGTCG
CCGCTGCCACTCTCTCGGATCGCTATATCACGTCTCGCTTCCTACCGGACAAAGCAATTGACCTGGTCGATGAGGCCGCG
AGCCGCCTGCGCATGGAGATCGATTCTTCCCCGCAAGAGATCGATGAGCTAGAGCGTGTTGTGCGTCGCCTGGAGATTGA
AGAAGTCGCACTGAGCAAGGAGACGGATGCGGCCTCTCAGCAGCGCCTGGAGAAGTTGCGCCAGGAGCTTGCCGACGAGC
GCGAGAAACTCGGCGAACTCAAAGCCCGCTGGAATAATGAGAAGTCTGCAATAGATAAGGTGCGCGAGGCCAAGGAAGAG
CTAGAGCATCTGCGCTCTGAGTCGGAGATTGCTGAGCGCGAAGGCGACTACGGCAAGGTGGCGGAGCTGCGCTATGGCCG
AATCCCAGAGTTGGAAAAGCAGGTGGCTGAGGCTGAGGCCCATACAACTGAGACCACTATGCTTTCGGAGGAGGTAACAC
CGGACACCATCGCTGATGTGGTTTCTGCTTGGACTGGTATCCCTGCGGGCAAGATGTTGCAGGGGGAGACGGAAAAGCTT
CTGCGCATGGAATCTGAGCTGGGTAGCCGAGTGGTTGGGCAGCTAGAAGCCGTTGAAGCTGTGTCTGATGCTGTGCGCCG
TGCGCGCGCTGGCGTAGCTGACCCGAACCGCCCGACTGGTTCCTTCCTTTTCCTTGGGCCTACGGGCGTGGGTAAGACTG
AGCTGGCTAAAGCTTTGGCCGAGTTCATGTTTGATGACGAGCGCGCGATGGTGCGCATAGATATGTCTGAGTACGGGGAG
AAGCATTCCGTGGCTCGACTTGTTGGTGCCCCTCCCGGATACGTTGGTTATGATCAAGGCGGTCAGCTCACCGAGGCTGT
GCGGCGGCGTCCCTACACGGTGGTGCTTTTTGACGAGGTAGAGAAAGCACATTCCGATGTCTTTGACATTCTGCTGCAGG
TACTCGATGAAGGCAGGCTTACCGACGGCCAAGGTCGTACCGTTGATTTCCGAAACACCGTGCTCATCCTCACCTCCAAC
CTGGGGGCTGGCGGTACTCGCGAGCAAATGATGGATGCCGTCAAACGAGCATTCAAACCGGAATTTGTTAACCGCCTGGA
TGACGTGGCGATCTTTGATCCGCTCTCAGAGGAGCAGCTCACTCATATTGTGGAGATCCAGATTGCTCAGCTGGCAAACC
GACTTTCGGCTCGTCGCCTGACCTTGCAGGTCTCTGATGCTGCAAAGTTGTGGTTGGCTGAACGCGGTTATGAGCCCGCC
TATGGCGCGCGTCCGCTGCGCCGTCTGATCCAACAGGCGATTGGTGATCAGCTGGCCAAGAAGCTGTTGGCAGGCGAGAT
CCGCGACGGCGACACCGTGCACGTAGATGTAGCCGATGGCGGCGAGGCTTTAGAGTTGGCAAAGAGATAA

Protein sequence :
MNSFNPTTKTQEALQVALQQASSLGNPDIRPAHLLAAILGQEDGIAVPVLRATGVDPQVVAKEANALVAGYPKAEGSGMA
NPNFNRDALNALTAAQELAGELGDEYVSTEVLLAAIARGKSDAAELLTKRGATYDVIKGVFPSVRGSKKVTSQDPEGQFQ
ALEKYSTDLTARAREGKIDPVIGRDSEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKGKTLIS
LDLGSMVAGAKYRGEFEERLKAVLDEIKSAEGEIITFIDELHTIVGAGATGDSAMDAGNMIKPLLARGELRLVGATTLDE
YRKYIEKDAALERRFQQVFVGEPSVEDAIGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPQEIDELERVVRRLEIEEVALSKETDAASQQRLEKLRQELADEREKLGELKARWNNEKSAIDKVREAKEE
LEHLRSESEIAEREGDYGKVAELRYGRIPELEKQVAEAEAHTTETTMLSEEVTPDTIADVVSAWTGIPAGKMLQGETEKL
LRMESELGSRVVGQLEAVEAVSDAVRRARAGVADPNRPTGSFLFLGPTGVGKTELAKALAEFMFDDERAMVRIDMSEYGE
KHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVVLFDEVEKAHSDVFDILLQVLDEGRLTDGQGRTVDFRNTVLILTSN
LGAGGTREQMMDAVKRAFKPEFVNRLDDVAIFDPLSEEQLTHIVEIQIAQLANRLSARRLTLQVSDAAKLWLAERGYEPA
YGARPLRRLIQQAIGDQLAKKLLAGEIRDGDTVHVDVADGGEALELAKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 6e-98 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 5e-98 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB1 YP_003784276.1 ATP-dependent Clp protease ATP-binding subunit VFG2084 Protein 6e-106 43
clpB1 YP_003784276.1 ATP-dependent Clp protease ATP-binding subunit VFG2076 Protein 8e-109 41