Gene Information

Name : exaC (Hsero_1896)
Accession : YP_003775313.1
Strain : Herbaspirillum seropedicae SmR1
Genome accession: NC_014323
Putative virulence/resistance : Virulence
Product : NAD+ dependent acetaldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.10
Position : 2152739 - 2154259 bp
Length : 1521 bp
Strand : +
Note : -

DNA sequence :
ATGAACCTGGCAGACATCAGCAAACTCGGCGTACGCGACCCCTTCAAGCAACGTTACGACAATTTCATCGGTGGCAAATT
CGTGCCGCCGGTCAAGGGTGAATACTTCGAGAACATCAGCCCGGTGATCGGACGCGCCTTCTGTGAAGTGGCCCGCTCCA
GCGCCGAAGACGTGGAGCTGGCGCTGGACGCCGCCCACGCAGCCAAGAAGAGCTGGGGCAAGACCTCCCCCACCGAGCGC
GCCAATATGCTGTTGAAGATCGCCGACCGCATGGAAGCCAACCTGGAGCTGCTGGCCACTGCCGAAACCCTGGACAACGG
CAAGCCCATCCGCGAGACCATGGCCGCCGACATCCCGCTGGCCATCGACCACTTCCGCTATTTCGCCGCTGCCGTGCGCA
CCCAGGAAGGCAGCATCTGCCCCATCGACAATGACACCTACGCCTACCACTTCCATGAGCCTCTGGGCGTGGTCGGCCAG
ATCATCCCCTGGAACTTCCCCATCCTGATGGCGGTGTGGAAACTGGCCCCGGCGCTGGCCGCCGGCAATTGCGTGGTGTT
AAAGCCCGCCGAGCAGACCCCGGCCTCCATCATGGTGCTGATCGAACTGATCGCCGACCTGATCCCGCCGGGCGTGGTCA
ACATCGTGCAGGGCTTTGGCGTGGAAGCCGGCAAGCCGCTGGCCTCCAACAAGCGTATCGCCAAGATCGCCTTCACTGGC
GAGACCACCACTGGCCGCCTGATCATGCAATACGCTTCGCAGAACCTGATCCCGGTGACGCTGGAGCTGGGCGGCAAGTC
GCCCAATATCTTCTTCGCCGACGTGCTGGACAAGGATGACGACTTCTTCGACAAGGCCCTGGAAGGCTTTGCCATGTTCG
CGCTGAACCAGGGCGAGGTCTGCACCTGCCCCTCGCGCGTGCTGGTGCAGGAATCGATCTACGAGCGCTTCATCGAGCGC
GCCTTGAAGCGCGTGGCGGCCATCAAGCAGGGCAATCCGCTGGACAAGAGCACCATGATCGGCGCGCAGGCCTCGCAGGA
ACAGCTGGAAAAGATCCTGTCCTACATCGACATCGGCAAGCAGGAAGGCGCCAAGGTGCTGGCCGGCGGCGGGCGCGAAG
AACTGGGCGGCGACCTGGCCTCGGGCTACTACGTCAAGCCGACCGTGTTCCAGGGCAATAACAAGATGCGCATCTTCCAG
GAAGAAATCTTTGGCCCGGTGGTCTCGGTGACCACCTTCAAGGATGAAGAAGAAGCGCTGGCCATTGCCAATGACACGCT
GTACGGCCTGGGCGCGGGCCTGTGGACCCGGGATGGCACGCGCGCCTTCCGCATGGGGCGTGAGATCCAGGCTGGCCGTG
TCTGGACCAACTGCTATCACCTCTATCCGGCGCATGCGGCCTTCGGCGGCTACAAGCAATCCGGCATCGGCCGCGAAAAC
CACAAGATGATGCTGGACCACTACCAGCAGACCAAGAACCTGCTGGTCAGCTACAGCCCGAAGGCGCTGGGCTTCTTCTG
A

Protein sequence :
MNLADISKLGVRDPFKQRYDNFIGGKFVPPVKGEYFENISPVIGRAFCEVARSSAEDVELALDAAHAAKKSWGKTSPTER
ANMLLKIADRMEANLELLATAETLDNGKPIRETMAADIPLAIDHFRYFAAAVRTQEGSICPIDNDTYAYHFHEPLGVVGQ
IIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTPASIMVLIELIADLIPPGVVNIVQGFGVEAGKPLASNKRIAKIAFTG
ETTTGRLIMQYASQNLIPVTLELGGKSPNIFFADVLDKDDDFFDKALEGFAMFALNQGEVCTCPSRVLVQESIYERFIER
ALKRVAAIKQGNPLDKSTMIGAQASQEQLEKILSYIDIGKQEGAKVLAGGGREELGGDLASGYYVKPTVFQGNNKMRIFQ
EEIFGPVVSVTTFKDEEEALAIANDTLYGLGAGLWTRDGTRAFRMGREIQAGRVWTNCYHLYPAHAAFGGYKQSGIGREN
HKMMLDHYQQTKNLLVSYSPKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-142 65
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-147 65
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-147 65
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-147 65
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-146 65
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-69 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
exaC YP_003775313.1 NAD+ dependent acetaldehyde dehydrogenase VFG0082 Protein 6e-143 65