Gene Information

Name : zntA (Hsero_1604)
Accession : YP_003775025.1
Strain : Herbaspirillum seropedicae SmR1
Genome accession: NC_014323
Putative virulence/resistance : Resistance
Product : metal-transporting P-type ATPase transmembrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.5
Position : 1829883 - 1832219 bp
Length : 2337 bp
Strand : -
Note : -

DNA sequence :
ATGGCGGAACATTCGCACAAGCACGATCACGATCACCTGCATGATCACGACCATGGCCATGAGCACGCACATGAGCACGA
CCATCATCACGCCCCCGCAACCTCCAGTTGCTGCGCCGGCCATGCATGCGCCAGCGAGCAGGAAAGGTCCGCGCCCATCC
CCGCCGCACGCCTGGAGGGAGCAACCGAAGAGGCGGTCTTCTTCATCCAGAAGATGGACTGCCCGACCGAAGAAAAGCTG
ATCCGCGAACGCCTCTCGCAGATGTCCGGCGTGGGTACGCTGGAATTCAACCTGATCCAGCGCGAGCTGACCGTGCAACA
CCAGTTGCCCTCCATCGCCCCGCTGGTGGCGACCCTCAAGGCGCTGGACATGCTGCCCGCCGTCAAATCCGACTCGCTCG
ACGCCGAGGCCGGCCGCGACGCACCTGACCAAGCCGCTGCCTACCGCATCCCGGCCCGGCGCTGGATCTTGCTGGGCCTG
GCCGGCGTAGCCGCGCTGGGCGCCGAAGTGCTGGCCTGGAGCAGCGGCGACGAGCGCTCGCTGCCGGTGATCGGGCTGGC
GCTCGCGGCCATCCTGCTGGGTGGGCTGGGCACGCTCAAGAAGGGCTGGATCGCCCTGCGCAACTTCTCGCTGAACATGA
ACTTCCTGATGTCGCTGGCCGTCATCGGTGCGGCCGTCATCGGCCAGTGGCCCGAAGCGGCGGTGGTGATCGTGCTGTTC
ACCCTGGCCGAGATGATCGAAGCGCTGTCGCTGGACCGCGCCCGCAATGCCATTGCCGGCCTGCTGGCGATGACGCCCGA
CATGGCCACGCGGCGCGGCGAGGACGGTGTCTGGTCAACTGTACCGGCCCGTACCGTGACAGTGGATGACACTGTACGGG
TCGCCCCTGGGGAACGTGTACCGCTGGATGGCCTGGTGCTGTCAGGCAGCACCAGCATCAACCAGGCGCCCATTACCGGA
GAAAGCATACCGGTACAGAAGCAGGCCGGTGATCCGGTCTTTGCCGGCACCATCAATGAACAGGGCGCCTTCGAGATGCG
CGTGACGGCGGCGCAAGGCGACTCCACGCTGGCGCGCATCGTCAAGAGCGTGCAGCAGGCGCAGGGCCAGCGCGCGCCGA
CCCAGCGCTTCGTGGACAACTTCGCCCGCTACTACATCCCTGCCGTGGTGGTCATGGCCGTGCTGGTGGCGCTGCTGCCG
CCGCTGCTGGCGGGTGCGGCCTTCCAGCCCTGGCTGTACAAGGCGCTGGTGCTGCTGGTGATCGCCTGTCCCTGCGCGCT
GGTCATCTCCACTCCCGTGACCATCGTCAGCGGCCTGGCCTCGGCGGCCCGCCACGGCATCCTGGTCAAGGGCGGCGTCT
ATCTGGAGCAGGGCCGCCAGCTGCGCGCCCTGGCGCTGGACAAGACCGGCACCCTCACCTTCGGCAAGCCGCGCGTGACC
GATGTGGTCTCGCTGCAGGCACAGGCGGACCAGCAGGCGCTGCTGCAACTGGCGGTCTCCCTGGCGGCCCGTTCGGACCA
CCCGGTCTCGCGCGCCATCGCCGCCCAGGAAGAGATCGCGACCGTGGAGGTGAGCGAATTCGCCGCCCTGGCCGGACGCG
GCGTGCAAGGACGCATCAACGGACAGTTGCTGCACCTGGGCAATCACCGCCTGGTCCACGAACTGGGCCAGTGCAGCCCG
GAACTGGAAGCGCGCCTGCAAGCCTTCGAGAAACAAGGCAAGACCACCACCGTGCTGTGCCTCGATGGTCAGCCGCAACT
GCTGGTGGCGGTGGCCGATACGGTGCGCCCCAGCAGCAGGCAAGCCGTGGCCGAGCTGCGCGCGCTGGGGGTGGAGGTCA
TCATGCTGACCGGCGACAACAGCCACACCGCCCAGGCCATCGCCGCCCAGACCGGCATCAGCGATGCCCGCGGCGACCAG
CTGCCGGAAGACAAGCTCAAGGCCATCGAAGAACTGAGCCAGCGTCACGGCGTGCGCGGCGTGGGCATGGTGGGCGACGG
CATCAACGATGCGCCGGCGCTGGCGCGGGCCGATATCGGGTTCGCCATGGGCGCGGCCGGCACCGACACGGCGCTGGAAA
CGGCCGACGTGGCCTTGATGGACGACGACCTGCGCAAGATTCCCGACTTCATTCGCCTGAGCCGCAAGGCCCATGCCGTG
CTGGTGCAGAACATCAGCATCGCGCTGGGCATCAAGGCGGTGTTCCTGGGCTTGGCGCTGGTGGGCATGAGTTCGCTGTG
GATGGCGGTGTTTGCCGACATGGGAGCCAGCCTGATCGTGGTCTTCAACGGCCTGCGCCTGGTGCGCGGCTTGCGCCAGC
GCAAGGCCGCCGCTTGA

Protein sequence :
MAEHSHKHDHDHLHDHDHGHEHAHEHDHHHAPATSSCCAGHACASEQERSAPIPAARLEGATEEAVFFIQKMDCPTEEKL
IRERLSQMSGVGTLEFNLIQRELTVQHQLPSIAPLVATLKALDMLPAVKSDSLDAEAGRDAPDQAAAYRIPARRWILLGL
AGVAALGAEVLAWSSGDERSLPVIGLALAAILLGGLGTLKKGWIALRNFSLNMNFLMSLAVIGAAVIGQWPEAAVVIVLF
TLAEMIEALSLDRARNAIAGLLAMTPDMATRRGEDGVWSTVPARTVTVDDTVRVAPGERVPLDGLVLSGSTSINQAPITG
ESIPVQKQAGDPVFAGTINEQGAFEMRVTAAQGDSTLARIVKSVQQAQGQRAPTQRFVDNFARYYIPAVVVMAVLVALLP
PLLAGAAFQPWLYKALVLLVIACPCALVISTPVTIVSGLASAARHGILVKGGVYLEQGRQLRALALDKTGTLTFGKPRVT
DVVSLQAQADQQALLQLAVSLAARSDHPVSRAIAAQEEIATVEVSEFAALAGRGVQGRINGQLLHLGNHRLVHELGQCSP
ELEARLQAFEKQGKTTTVLCLDGQPQLLVAVADTVRPSSRQAVAELRALGVEVIMLTGDNSHTAQAIAAQTGISDARGDQ
LPEDKLKAIEELSQRHGVRGVGMVGDGINDAPALARADIGFAMGAAGTDTALETADVALMDDDLRKIPDFIRLSRKAHAV
LVQNISIALGIKAVFLGLALVGMSSLWMAVFADMGASLIVVFNGLRLVRGLRQRKAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 6e-168 62
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 6e-108 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-108 46
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-108 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
zntA YP_003775025.1 metal-transporting P-type ATPase transmembrane protein BAC0298 Protein 2e-161 60
zntA YP_003775025.1 metal-transporting P-type ATPase transmembrane protein BAC0461 Protein 1e-77 43
zntA YP_003775025.1 metal-transporting P-type ATPase transmembrane protein BAC0092 Protein 1e-73 41
zntA YP_003775025.1 metal-transporting P-type ATPase transmembrane protein BAC0100 Protein 4e-57 41