Gene Information

Name : vanH (AMED_8290)
Accession : YP_003770390.1
Strain : Amycolatopsis mediterranei U32
Genome accession: NC_014318
Putative virulence/resistance : Resistance
Product : D-lactate dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 9116519 - 9117472 bp
Length : 954 bp
Strand : -
Note : -

DNA sequence :
ATGACGATCTACGGGTGTGCACCCGACGAAGCCGTGCTGTTCCGGGAGATGGCGCCGGGCTTCGGGGTGACACCGACCAT
CACCGGTGCGGCGGTGTCCGAGGCCAACGCCGCACTGGCGGCCGGTAACCGGTGCGTCAGCGTCGGGCACAAGACGCCGC
TCACCCGGAGAACTCTTCTCGCGCTCAGCCGGGTCGGCGTCACCTACGTCTCCACGAGGAGCGTCGGCTACGACCACATC
GACGTCGGATACGCCCGGAGCGTCGGCATTTCCGTCGGGAACGTCGCCTATTCGCCGGACAGCGTGGCCGACTACACGCT
GATGCTGATGTTGATGCTCGTGCGGGACGCCAAGTCCGTCATCCGCCGCGCGGAGGAGCACGACTACCGGCTGAACGACG
TGCGCGGGAAAGAGCTGCGCGATCTGACCGTCGGGGTGGTCGGGACCGGACGCATCGGTTCCGCCGTCGTCGGCCGGTTG
CGCGGGTTCGGGGCTCGGGTGGTGGCTCACGACTGCTGTCCCCAGGCCGGCCTCGACTACGTCGAACTCGACGAACTGCT
GCGGCTGAGCGACATCGTCACGCTCCACACGCCACTCGACGCCGGAACGCACCACCTCCTGGACCGACGGCGGCTCGAGC
GGATGAAGCCCGGAGCGTTCGTCGTCAACACCGGGCGAGGCCCCCTTCTCGACACCGAGGCGCTCGTCGCGGCACTGGAA
AACGGCAGGCTGGGCGGCGCCGCGCTGGACGTCCTCGAAGGGGAAGAAGGCGTCTTCTACGCCGACTGCCGCGATCGGCC
CGTCGACAGCGACCTGCTGGTGCGGCTGCAGAAGCTGCCGAACGTGCTGATCAGCCCGCACACCGCGTACTACACCGACC
ACGCGCTCGGCGACACCGTCGAAAACTCCATCATCAACTGCTTGAACTTCGAAAGCGGGAAGCGGCATGAATAG

Protein sequence :
MTIYGCAPDEAVLFREMAPGFGVTPTITGAAVSEANAALAAGNRCVSVGHKTPLTRRTLLALSRVGVTYVSTRSVGYDHI
DVGYARSVGISVGNVAYSPDSVADYTLMLMLMLVRDAKSVIRRAEEHDYRLNDVRGKELRDLTVGVVGTGRIGSAVVGRL
RGFGARVVAHDCCPQAGLDYVELDELLRLSDIVTLHTPLDAGTHHLLDRRRLERMKPGAFVVNTGRGPLLDTEALVAALE
NGRLGGAALDVLEGEEGVFYADCRDRPVDSDLLVRLQKLPNVLISPHTAYYTDHALGDTVENSIINCLNFESGKRHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 5e-87 59
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-86 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vanH YP_003770390.1 D-lactate dehydrogenase AF155139.2.orf4.gene Protein 9e-92 62
vanH YP_003770390.1 D-lactate dehydrogenase NC_005054.2598279.p0 Protein 3e-91 59
vanH YP_003770390.1 D-lactate dehydrogenase NC_014475.1.orf2.gen Protein 3e-91 59
vanH YP_003770390.1 D-lactate dehydrogenase U35369.1.gene5.p01 Protein 1e-86 59
vanH YP_003770390.1 D-lactate dehydrogenase AF310956.2.orf4.gene Protein 4e-87 59
vanH YP_003770390.1 D-lactate dehydrogenase FJ349556.1.orf3.gene Protein 2e-87 56
vanH YP_003770390.1 D-lactate dehydrogenase AF130997.1.orf3.gene Protein 2e-78 56