Gene Information

Name : ampC (AMED_5124)
Accession : YP_003767291.1
Strain : Amycolatopsis mediterranei U32
Genome accession: NC_014318
Putative virulence/resistance : Resistance
Product : beta-lactamase class A
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : -
Position : 5683129 - 5684028 bp
Length : 900 bp
Strand : +
Note : -

DNA sequence :
GTGCCGTTCCCCCGAGCCCGGCGGGCCGCGCTCGCCGCGCTGCTCCTCGTTCCGCTGGCCGCCTGCACCGCGCAAGCGCC
CCAGCCGGCACCGGCATCGGCAGCGACCCCGGCAGCGGCCCCGCAGCCGGACTTCGCCCCGCTCGAACGCAGCTTCGACG
CCCGCCTCGGCGTGTACGCCCTCGACACCGGCTCGGGTCGCGAGATCACCCACCGCGCCGACGAGCGCTTCGGCTACGCC
TCGACGCACAAGGTGTTCTCCGCCGGGGCCGTCCTCCGGCGCACCAGCCTCGACGGGCTCGCGAAGAACCTGACCTACAC
CCGCGCCGACCTGCAGCCGAACTCCCCCGTCACCGAGAAGCACGTCACCACCGGCCTGTCGCTGCGCGAGGCGATGGACG
CCACGCTGCGCTACAGCGACAACACGGCCGCGAACCTGCTGTTCCGCGAGCTCGGCGGGCCGGCCGGGCTCGCCGCCGCG
CTGCGCGAGATCGGCGACACGACCACCCACGCCGACCGGATCGAACCGGGCCTCAACGACCTCGCGCCGGGCGACGTCCG
GGACACGAGCACCCCGCGCGCGATGGCCGGCAGCCTGCGGGCGTTCGCCCTCGGCCCCGCGCTGCCGCCGGAAAAGCAGA
CCGTGCTCACCGACATGATGCGCGCCAACACGACCGGCGCGGCCCTGATCCGGGCGGGCGCGCCGGCCGGCTGGGCGGTC
GCCGACAAGACCGGGTCCGGCAGCTACGCCACGCGCAACGACATCGCGGTCGTCTGGCCGCCGGGGCGCGCGCCGATCGT
GCTGATCGTCATGTCCAGCCGCCAGGCCGAGAGCGCCGATCACGACGACCGGCTCATCGCGCAGGCCGCGAAGCTGGCCC
TCGACGCCTTCCGAAGCTAA

Protein sequence :
MPFPRARRAALAALLLVPLAACTAQAPQPAPASAATPAAAPQPDFAPLERSFDARLGVYALDTGSGREITHRADERFGYA
STHKVFSAGAVLRRTSLDGLAKNLTYTRADLQPNSPVTEKHVTTGLSLREAMDATLRYSDNTAANLLFRELGGPAGLAAA
LREIGDTTTHADRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQTVLTDMMRANTTGAALIRAGAPAGWAV
ADKTGSGSYATRNDIAVVWPPGRAPIVLIVMSSRQAESADHDDRLIAQAAKLALDAFRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 1e-39 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ampC YP_003767291.1 beta-lactamase class A AF367983.gene.p01 Protein 2e-63 55
ampC YP_003767291.1 beta-lactamase class A AF395881.gene.p01 Protein 4e-42 53
ampC YP_003767291.1 beta-lactamase class A FJ234412.1.gene1.p01 Protein 3e-42 53
ampC YP_003767291.1 beta-lactamase class A EU729727.1.gene1.p1 Protein 6e-42 53
ampC YP_003767291.1 beta-lactamase class A GQ140348.1.gene1.p01 Protein 2e-41 52
ampC YP_003767291.1 beta-lactamase class A AF297554.1.gene1.p1 Protein 2e-42 50
ampC YP_003767291.1 beta-lactamase class A HM066995.1.gene1.p01 Protein 1e-41 50
ampC YP_003767291.1 beta-lactamase class A AY034847.1.gene1.p01 Protein 9e-43 50
ampC YP_003767291.1 beta-lactamase class A HQ641421.1.gene1.p01 Protein 2e-42 50
ampC YP_003767291.1 beta-lactamase class A EU555534.1.gene1.p01 Protein 6e-43 50
ampC YP_003767291.1 beta-lactamase class A DQ663489.gene.p01 Protein 1e-40 49
ampC YP_003767291.1 beta-lactamase class A DQ328639.gene.p01 Protein 9e-41 49
ampC YP_003767291.1 beta-lactamase class A AY005110.1.gene1.p1 Protein 1e-39 49
ampC YP_003767291.1 beta-lactamase class A AB284167.2.gene1.p01 Protein 1e-40 48
ampC YP_003767291.1 beta-lactamase class A AY033516.1.gene2.p01 Protein 2e-41 48
ampC YP_003767291.1 beta-lactamase class A AY303807.gene.p01 Protein 6e-40 47
ampC YP_003767291.1 beta-lactamase class A AY156923.1.gene1.p01 Protein 1e-41 47
ampC YP_003767291.1 beta-lactamase class A AF325134.1.gene1.p1 Protein 6e-41 47
ampC YP_003767291.1 beta-lactamase class A AF252622.2.gene2.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A AY847146.1.gene1.p01 Protein 3e-41 47
ampC YP_003767291.1 beta-lactamase class A HQ398215.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A HM803271.1.gene1.p01 Protein 4e-41 47
ampC YP_003767291.1 beta-lactamase class A EF418608.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A AY847147.1.gene1.p01 Protein 3e-41 47
ampC YP_003767291.1 beta-lactamase class A AY847143.1.gene1.p01 Protein 4e-41 47
ampC YP_003767291.1 beta-lactamase class A AY822595.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A AJ416345.gene.p01 Protein 5e-41 47
ampC YP_003767291.1 beta-lactamase class A JF274243.1.gene1.p01 Protein 1e-41 47
ampC YP_003767291.1 beta-lactamase class A FJ907381.1.gene1.p01 Protein 3e-41 47
ampC YP_003767291.1 beta-lactamase class A AY847145.1.gene1.p01 Protein 7e-41 47
ampC YP_003767291.1 beta-lactamase class A HQ833652.1.gene1.p01 Protein 8e-42 47
ampC YP_003767291.1 beta-lactamase class A HQ913565.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A FJ214366.1.gene1.p1 Protein 3e-41 47
ampC YP_003767291.1 beta-lactamase class A AF252623.2.gene1.p01 Protein 1e-41 47
ampC YP_003767291.1 beta-lactamase class A AY238472.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A AF189721.1.gene1.p01 Protein 4e-41 47
ampC YP_003767291.1 beta-lactamase class A EU136031.3.gene1.p3 Protein 9e-41 47
ampC YP_003767291.1 beta-lactamase class A JF274247.1.gene1.p01 Protein 5e-42 47
ampC YP_003767291.1 beta-lactamase class A EF581888.1.gene1.p01 Protein 1e-41 47
ampC YP_003767291.1 beta-lactamase class A AF325133.1.gene1.p1 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A AY029068.1.gene1.p1 Protein 4e-41 47
ampC YP_003767291.1 beta-lactamase class A HQ166709.1.gene1.p01 Protein 9e-41 47
ampC YP_003767291.1 beta-lactamase class A FJ214368.1.gene1.p1 Protein 2e-40 47
ampC YP_003767291.1 beta-lactamase class A AY143430.1.gene1.p01 Protein 1e-41 47
ampC YP_003767291.1 beta-lactamase class A AF174129.3.gene9.p01 Protein 5e-41 47
ampC YP_003767291.1 beta-lactamase class A AY847144.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A JF274246.1.gene1.p01 Protein 3e-41 47
ampC YP_003767291.1 beta-lactamase class A HM755448.1.gene1.p01 Protein 2e-41 47
ampC YP_003767291.1 beta-lactamase class A FJ214367.1.gene1.p1 Protein 1e-41 47
ampC YP_003767291.1 beta-lactamase class A HQ833651.1.gene1.p01 Protein 3e-41 47
ampC YP_003767291.1 beta-lactamase class A FJ214369.1.gene1.p1 Protein 1e-40 47
ampC YP_003767291.1 beta-lactamase class A JF274242.1.gene1.p01 Protein 1e-40 47
ampC YP_003767291.1 beta-lactamase class A AY750914.gene.p01 Protein 1e-40 46
ampC YP_003767291.1 beta-lactamase class A AB205197.1.gene1.p01 Protein 6e-41 46
ampC YP_003767291.1 beta-lactamase class A DQ885477.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A GU127598.1.gene1.p1 Protein 4e-40 46
ampC YP_003767291.1 beta-lactamase class A JN227085.1.gene1.p01 Protein 9e-41 46
ampC YP_003767291.1 beta-lactamase class A AY847148.1.gene1.p01 Protein 3e-40 46
ampC YP_003767291.1 beta-lactamase class A FJ873739.1.gene1.p01 Protein 1e-41 46
ampC YP_003767291.1 beta-lactamase class A AY649755.1.gene1.p01 Protein 1e-40 46
ampC YP_003767291.1 beta-lactamase class A AY157676.1.gene1.p01 Protein 9e-39 46
ampC YP_003767291.1 beta-lactamase class A DQ211987.1.gene1.p01 Protein 9e-41 46
ampC YP_003767291.1 beta-lactamase class A AJ549244.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A AF255298.1.gene1.p1 Protein 1e-40 46
ampC YP_003767291.1 beta-lactamase class A HM167760.1.gene1.p01 Protein 6e-39 46
ampC YP_003767291.1 beta-lactamase class A DQ256091.1.gene1.p1 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A FJ815436.1.gene1.p01 Protein 1e-40 46
ampC YP_003767291.1 beta-lactamase class A EU177100.1.gene1.p01 Protein 2e-41 46
ampC YP_003767291.1 beta-lactamase class A DQ810789.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A EU202673.2.gene1.p2 Protein 3e-41 46
ampC YP_003767291.1 beta-lactamase class A EU545409.1.gene1.p1 Protein 3e-40 46
ampC YP_003767291.1 beta-lactamase class A AF305837.gene.p01 Protein 2e-41 46
ampC YP_003767291.1 beta-lactamase class A AB177384.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A Y10278.1.gene1.p01 Protein 3e-41 46
ampC YP_003767291.1 beta-lactamase class A AY995206.gene.p01 Protein 2e-41 46
ampC YP_003767291.1 beta-lactamase class A AY292654.1.gene1.p1 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A AY080894.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A HQ398214.1.gene1.p01 Protein 8e-42 46
ampC YP_003767291.1 beta-lactamase class A AM411407.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A AY598759.gene.p01 Protein 1e-40 46
ampC YP_003767291.1 beta-lactamase class A AM982522.2.gene1.p01 Protein 5e-39 46
ampC YP_003767291.1 beta-lactamase class A EF219142.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A DQ061159.1.gene1.p01 Protein 1e-40 46
ampC YP_003767291.1 beta-lactamase class A AJ704396.1.gene1.p01 Protein 2e-41 46
ampC YP_003767291.1 beta-lactamase class A AY267213.1.gene1.p01 Protein 4e-41 46
ampC YP_003767291.1 beta-lactamase class A EU402393.1.gene1.p1 Protein 4e-41 45
ampC YP_003767291.1 beta-lactamase class A AJ567481.1.gene1.p01 Protein 1e-39 45
ampC YP_003767291.1 beta-lactamase class A EF426798.1.gene1.p1 Protein 6e-41 45
ampC YP_003767291.1 beta-lactamase class A DQ102702.1.gene1.p1 Protein 4e-40 45
ampC YP_003767291.1 beta-lactamase class A DQ125241.gene.p01 Protein 7e-40 45
ampC YP_003767291.1 beta-lactamase class A EF374097.1.gene1.p01 Protein 4e-40 45
ampC YP_003767291.1 beta-lactamase class A AF518567.2.gene4.p01 Protein 4e-38 45
ampC YP_003767291.1 beta-lactamase class A GQ149244.1.gene1.p01 Protein 7e-40 45
ampC YP_003767291.1 beta-lactamase class A DQ268764.2.gene6.p01 Protein 5e-41 45
ampC YP_003767291.1 beta-lactamase class A AF488377.1.gene1.p1 Protein 3e-40 45
ampC YP_003767291.1 beta-lactamase class A GQ149243.1.gene1.p01 Protein 3e-39 45
ampC YP_003767291.1 beta-lactamase class A X92506.gene.p01 Protein 6e-41 45
ampC YP_003767291.1 beta-lactamase class A AY954516.1.gene1.p1 Protein 3e-38 45
ampC YP_003767291.1 beta-lactamase class A AJ416344.1.gene1.p01 Protein 1e-39 45
ampC YP_003767291.1 beta-lactamase class A GQ351346.1.gene1.p01 Protein 1e-40 45
ampC YP_003767291.1 beta-lactamase class A AY515297.1.gene1.p1 Protein 4e-40 45
ampC YP_003767291.1 beta-lactamase class A Y14156.1.gene1.p01 Protein 2e-38 45
ampC YP_003767291.1 beta-lactamase class A DQ408762.1.gene1.p1 Protein 8e-40 45
ampC YP_003767291.1 beta-lactamase class A U95364.1.gene1.p01 Protein 4e-40 45
ampC YP_003767291.1 beta-lactamase class A DQ023162.1.gene1.p1 Protein 7e-39 45
ampC YP_003767291.1 beta-lactamase class A FJ971899.1.gene1.p1 Protein 5e-38 45
ampC YP_003767291.1 beta-lactamase class A DQ223685.1.gene1.p01 Protein 2e-40 45
ampC YP_003767291.1 beta-lactamase class A X92507.1.gene1.p01 Protein 7e-40 45
ampC YP_003767291.1 beta-lactamase class A AJ557142.gene.p01 Protein 5e-41 45
ampC YP_003767291.1 beta-lactamase class A JF966749.1.gene1.p01 Protein 7e-41 45
ampC YP_003767291.1 beta-lactamase class A HM776707.1.gene1.p1 Protein 7e-40 45
ampC YP_003767291.1 beta-lactamase class A GQ870432.1.gene1.p1 Protein 4e-38 45
ampC YP_003767291.1 beta-lactamase class A EF210159.1.gene1.p01 Protein 3e-40 45
ampC YP_003767291.1 beta-lactamase class A AF275256.gene.p01 Protein 3e-40 45
ampC YP_003767291.1 beta-lactamase class A U50278.1.gene2.p01 Protein 2e-40 44
ampC YP_003767291.1 beta-lactamase class A AJ005045.gene.p01 Protein 7e-38 44
ampC YP_003767291.1 beta-lactamase class A Z28968.gene.p01 Protein 2e-38 44
ampC YP_003767291.1 beta-lactamase class A AY178993.1.gene1.p01 Protein 3e-32 44
ampC YP_003767291.1 beta-lactamase class A AF135373.1.gene1.p01 Protein 3e-32 44
ampC YP_003767291.1 beta-lactamase class A AY130284.1.gene1.p1 Protein 3e-27 42
ampC YP_003767291.1 beta-lactamase class A AY130285.1.gene1.p1 Protein 3e-27 42
ampC YP_003767291.1 beta-lactamase class A JF949915.1.gene1.p01 Protein 6e-27 42
ampC YP_003767291.1 beta-lactamase class A JF949916.1.gene1.p01 Protein 1e-26 42
ampC YP_003767291.1 beta-lactamase class A AY130282.1.gene1.p1 Protein 1e-26 42
ampC YP_003767291.1 beta-lactamase class A JN051143.1.gene1.p01 Protein 8e-27 42
ampC YP_003767291.1 beta-lactamase class A AM176554.2.gene1.p01 Protein 5e-27 42
ampC YP_003767291.1 beta-lactamase class A EU274581.1.gene1.p1 Protein 1e-26 42
ampC YP_003767291.1 beta-lactamase class A AY072920.1.gene1.p1 Protein 4e-28 42
ampC YP_003767291.1 beta-lactamase class A FJ919776.1.gene1.p01 Protein 4e-28 42
ampC YP_003767291.1 beta-lactamase class A EU032604.1.gene1.p01 Protein 9e-27 42
ampC YP_003767291.1 beta-lactamase class A DQ174308.1.gene1.p01 Protein 1e-26 42
ampC YP_003767291.1 beta-lactamase class A HM246246.1.gene1.p1 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A AF516719.1.gene1.p1 Protein 9e-28 41
ampC YP_003767291.1 beta-lactamase class A FJ360884.1.gene1.p01 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A Y10280.1.gene1.p01 Protein 1e-27 41
ampC YP_003767291.1 beta-lactamase class A HQ661363.1.gene1.p1 Protein 1e-26 41
ampC YP_003767291.1 beta-lactamase class A Y10281.1.gene1.p01 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A AJ277415.1.gene1.p01 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A AY037780.1.gene1.p01 Protein 7e-28 41
ampC YP_003767291.1 beta-lactamase class A AF495873.1.gene1.p1 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A AF468003.1.gene1.p1 Protein 1e-27 41
ampC YP_003767291.1 beta-lactamase class A AJ277414.1.gene1.p01 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A Y10279.1.gene1.p01 Protein 9e-28 41
ampC YP_003767291.1 beta-lactamase class A AJ239002.1.gene1.p01 Protein 2e-27 41
ampC YP_003767291.1 beta-lactamase class A AF427130.1.gene1.p01 Protein 6e-28 41
ampC YP_003767291.1 beta-lactamase class A AF347054.1.gene1.p1 Protein 9e-28 41
ampC YP_003767291.1 beta-lactamase class A AF190693.1.gene1.p01 Protein 2e-28 41
ampC YP_003767291.1 beta-lactamase class A AM941159.1.gene1.p01 Protein 5e-28 41
ampC YP_003767291.1 beta-lactamase class A AF188199.1.gene1.p01 Protein 4e-28 41
ampC YP_003767291.1 beta-lactamase class A JN416112.1.gene1.p01 Protein 3e-28 41