Gene Information

Name : Nwat_1262 (Nwat_1262)
Accession : YP_003760510.1
Strain : Nitrosococcus watsonii C-113
Genome accession: NC_014315
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 1354656 - 1356140 bp
Length : 1485 bp
Strand : +
Note : KEGG: bld:BLi02249 DhaS; PFAM: Aldehyde Dehydrogenase

DNA sequence :
GTGAGTGTTTTAAAAATTAATCCAAACTCGAAGGTAGAGAAATTTCTTAATGGTACAAAGCGGATGTACATTAATGGGGA
ATTTGTAAAAAGTAAATCGCAAAAAACGTTCGAAACGTATAATCCTGCAACAGGAGAAGTATTGGCAACTGTATTTGAAG
GAGGACCAGAGGATGTTGATGTTGCGGTAAAAGCTGCTCGTGAGGCTTTTGATAACGGTCCATGGCTAAAAATGAGTGCT
GCTGAAAGAAGCAGAATTATGTATAAACTAGCGGATCTGATGGAAGAGCATGCAGAAGAATTAGCACTGCTTGAAACATT
AGATAATGGAAAACCAATCCGTGAATCTAGAAATATGGATGTGCCGCTTTCGGTGGAACATATGCGGTATTATGCTGGTT
GGCCTACAAAAATTGTCGGTCAAACGATTCCGGTAAGTGGCCCGTATTTTAATTACTCACGTCATGAACCGTTGGGAGTC
GTGGGACAAATTATTCCATGGAATTTACCATTGCTTATGGCGATGTATAAAATGGGTGCGGCATTGGCAATGGGATGTAC
GATGGTTCTTAAGCCTTCAGAACTAACACCCCTGTCAACTTTATACTTGGCGGAGTTAACGGAAAAAGCGGGGTTTCCTC
CGGGTGTTTTCAATGTAGTTCCCGGTTTTGGTGGACCCGTTGGCGTACCATTAGTTGAACATCCGCTGGTTGATAAAATT
GGATTTACGGGTTCTACACAGACCGGCAAAGTGATTATGCAAAATGCCGCAAAAACGTTAAAAGATATTACCTTAGAACT
TGGTGGAAAATCCCCTAATATCATCATGCCAGATGCTGATTTATCTAAAGCAATCCCAGGTGCATTGAATGGAGTCATGA
TCAATCAAGGCCAAAATTGTACAGCAGGCTCCCGTGTCTTTGTTCATAAGAAGCATTATGATAATGTTGTGGCAGAAATG
ATTGATTATGCCAATAATATTAAACAAGGACCTGGAATTTATAATGATACTGAAATAGGACCTCTAATATCGATAGGTCA
GCAAGAAAGGGTATTAAGTTATATTGAGAAAGGGGTTAGTGAAGGGGCAGAATTGGTTGCTGGTGGTAAAAAATTTCAGG
AGGAAGGATACTTTGTAAAGCCAACCGTGTTTGCCAATGTACGCGATAAAATGGTTATTGCTAAGGAAGAGATCTTTGGA
CCCGTTCTTGCCGCAATTCTGTTTGATGACCTGGATGACTTGATTGAACGTGCTAACAATACACCGTATGGCCTAGCTGC
CGGATTGTGGACACGGGATGTGACAAATGCACATTATATTGCAGCAAAACTCCGTGCCGGTACAGTTTGGGTGAATTGCT
ATAATGTTTTTGATGTTGCTACACCATTTGGTGGGTTTAAGCAATCTGGCATTGGACGCGAATTAGGCTCATACGCCCTG
AATAATTATACTGCGGTTAAGAGTGTTTGGATTGCGATGGATTAA

Protein sequence :
MSVLKINPNSKVEKFLNGTKRMYINGEFVKSKSQKTFETYNPATGEVLATVFEGGPEDVDVAVKAAREAFDNGPWLKMSA
AERSRIMYKLADLMEEHAEELALLETLDNGKPIRESRNMDVPLSVEHMRYYAGWPTKIVGQTIPVSGPYFNYSRHEPLGV
VGQIIPWNLPLLMAMYKMGAALAMGCTMVLKPSELTPLSTLYLAELTEKAGFPPGVFNVVPGFGGPVGVPLVEHPLVDKI
GFTGSTQTGKVIMQNAAKTLKDITLELGGKSPNIIMPDADLSKAIPGALNGVMINQGQNCTAGSRVFVHKKHYDNVVAEM
IDYANNIKQGPGIYNDTEIGPLISIGQQERVLSYIEKGVSEGAELVAGGKKFQEEGYFVKPTVFANVRDKMVIAKEEIFG
PVLAAILFDDLDDLIERANNTPYGLAAGLWTRDVTNAHYIAAKLRAGTVWVNCYNVFDVATPFGGFKQSGIGRELGSYAL
NNYTAVKSVWIAMD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-69 46
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-74 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-75 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-75 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-75 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-75 44
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-61 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nwat_1262 YP_003760510.1 betaine-aldehyde dehydrogenase VFG0082 Protein 2e-74 44