Gene Information

Name : Hden_0349 (Hden_0349)
Accession : YP_003754495.1
Strain : Hyphomicrobium denitrificans ATCC 51888
Genome accession: NC_014313
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 356715 - 357392 bp
Length : 678 bp
Strand : +
Note : KEGG: rle:RL1157 two-component response regulator transcriptional regulatory protein; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver; transcriptional regulator

DNA sequence : 
ATGCGAATTCTTCTCATCGAAGACGACGACCAGACGGCAAAACTCGTCAAACAAAGTCTCGTCAAACATGGCTACGATGT
TGATGTCTCGAACGACGGCCAGAACGGTTTTAAGCATGCCGTTGTGGGCGGGTTCGACGTCTTGGTCATCGACCGGATGC
TGCCCGGATTGGACGGACTATCCATCGTTCAACGTCTTCGCGCGGCCCGCGTGAGTTCGCCGATCCTGTTTTTGACTGCC
GTTGGCGGCATCGAAGACCGAATAGAAGGCTTTGAAAGCGGAGCCGACGATTATCTTGTGAAACCATTTGCGCTCGGCGA
ACTCGTCGCGAGGGTCGCGGCGCTCGGCCGGCGGCCTCCGATAGCGCATGAAGATTTCTATTATAGGATTGCCGATCTCG
AAGTCGATTTGATCAAGCGCGAGATCAAGCGCGGCGGAGAGATCATCCGTCTGCAGCCCCGTGAGTTCCGCATGCTGGAA
ATTCTGGTGCGCAACCGTGGGCGCGTCGTCACACGCTCGATGCTGCTCGAACAAGTTTGGGATTTGGAACTCGATCCCAA
AACTTCTATCGTGCAAACGAATGTCAGCCGCTTGCGATTAAAAATCGATCGGCCCGGCGACATTCCGTTGATCCGCACCG
TAAGAGGTCTTGGCTATCGCATCGATGACAAAGACTAG

Protein sequence : 
MRILLIEDDDQTAKLVKQSLVKHGYDVDVSNDGQNGFKHAVVGGFDVLVIDRMLPGLDGLSIVQRLRAARVSSPILFLTA
VGGIEDRIEGFESGADDYLVKPFALGELVARVAALGRRPPIAHEDFYYRIADLEVDLIKREIKRGGEIIRLQPREFRMLE
ILVRNRGRVVTRSMLLEQVWDLELDPKTSIVQTNVSRLRLKIDRPGDIPLIRTVRGLGYRIDDKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-38 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-39 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0125 Protein 3e-42 44
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0083 Protein 8e-47 44
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0111 Protein 3e-46 44
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0638 Protein 1e-40 44
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0197 Protein 7e-42 43
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0308 Protein 8e-42 42
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator BAC0347 Protein 1e-39 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator VFG1390 Protein 1e-36 43
Hden_0349 YP_003754495.1 winged helix family two component transcriptional regulator VFG0596 Protein 8e-39 42