Gene Information

Name : Hden_2809 (Hden_2809)
Accession : YP_003756926.1
Strain : Hyphomicrobium denitrificans ATCC 51888
Genome accession: NC_014313
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2893798 - 2895510 bp
Length : 1713 bp
Strand : -
Note : TIGRFAM: urease subunit alpha; KEGG: mex:Mext_1197 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
TTGGCTGTACTTTCACGTCGCGACTACGCCGCTATGTACGGTCCCACGGTTGGGGATGGCGTCCGTTTGGGAGACACCTC
GCTCGTTGCGGTGATCGAGAAAGATTTCGCGAGCTATGGCGACGAATGCCTTCACGGCGGCGGCAAGACGCTTCGCGACG
GAGCCGGGCTCGCGGCTGGCGTAACAAGCACTGAGGGAGCGCTGGATTTCCTGCTTTGCAATGTGACCGTCATCGATGCT
GTCGTCGGGATCGTCAAAGGTGATCTCGGCATCAAGGACGGCAAAATTGTCGGAATCGGCAAAGCGGGAAATCCGGCCAT
TATGGATGGCGTCGATCCGAGACTGATCGTTTCAGCCGCAACCGCCGTGCGCGACTGCGAGGGATTGATTGCCACGGCCG
GCGGCATAGACGTGCACGTTCATTTCGACAGCGCGCAGCTGTGCGATCACGCGATTGCGTCGGGCATTACAACCCTGCTC
GGCGGTTCTCTCGGCCCAATCACGGTCGGCATCGACTGCGGTGGCGCATTCAACGTCGGAAAAATGCTGCAGGCGGCGGA
GCAGTGGCCGGTCAATTTCGGATTTCTCGGTCGCGGTAATTCGCACAAGCCGGCTTCTCTCGTCGAGCAGATCGAAGCCG
GCTGCCTGGGGCTGAAACTTCACGAAGACTGGGGGTCGATGCCGTCGGCGATCGATACCTGTCTCGCACTTGCCGACGAC
ATGGACTTCCCCGTCCAAATTCATACCGACACGCTGAATGAGTCTGGGTTCGTCGAGGATACGCTAGCGGCGATCGCGGA
GCGTACCATTCACATGTACCACACGGAAGGCGCGGGAGGCGGGCACGCGCCTGACATCATTCGCGTCGCGGGCCTTCCCT
GGTGTCTGCCGTCTTCAACCAATCCCACCAATCCGTACACGATCAATACGTTCGACGAACATCTCGATATGACGATGGTT
TGTCACCATTTGAACCCGGCAATCCCTGAAGACGTGGCGTTCGCGGAAAGCCGCATCCGCGCTCAGACAATCGCGGCGGA
GGATATTCTTCACGATATCGGCGCGATCTCGATGCTCGGCTCGGACAGTCAGGGCATGGGGCGTATCAACGAGGTCATAT
GTAGAACGTGGCAGCTCGCCGACAAGATGAAAAGTCAGCGGGGACGTCTGCCTGAGGAATCGACGCCGTTCGGCGATAAC
GAGCGTATCAAGCGGTACGTTGCCAAATACACGATCAATCCGGCACGCACTTTCGGCATTGCCGATCACATCGGCTCGCT
GGAGGACGGCAAGCTCGCGGATATCGTTGTCTGGAGCCCGGCGTTTTTTGGCATCAAACCGGAGCTGATCCTCAAGGGCG
GCTTCATCGCGTGGGGCGCGATGGGAGACAGCTCGGCGTCTCTCATGACATGCGAACCGAGGGCGCTGCGACCGCAATGG
GGAGCGTTCGGCCGCGCCAGCCCGGCGTTGTCGGCATGCTTCGTCAACCCGGCCGCAATCGATCGCGGCATCTCGAAGAC
GTTGGACCTGAAAAAGAACCTGCTGCCCGCACGCGGAACGCGTCGCCTGTCGAAAAAGGACATGCTGCGCAACGACGCCT
GCCCGGACATTCGCGTCGATCCGCAGACGTTCGATGTTTTCGTCGATGGCGAGCTGGCGACCTGTGAGCCCGCACATGAG
CTGCCGTTATCACAACGATATATGTTGAGGTGA

Protein sequence :
MAVLSRRDYAAMYGPTVGDGVRLGDTSLVAVIEKDFASYGDECLHGGGKTLRDGAGLAAGVTSTEGALDFLLCNVTVIDA
VVGIVKGDLGIKDGKIVGIGKAGNPAIMDGVDPRLIVSAATAVRDCEGLIATAGGIDVHVHFDSAQLCDHAIASGITTLL
GGSLGPITVGIDCGGAFNVGKMLQAAEQWPVNFGFLGRGNSHKPASLVEQIEAGCLGLKLHEDWGSMPSAIDTCLALADD
MDFPVQIHTDTLNESGFVEDTLAAIAERTIHMYHTEGAGGGHAPDIIRVAGLPWCLPSSTNPTNPYTINTFDEHLDMTMV
CHHLNPAIPEDVAFAESRIRAQTIAAEDILHDIGAISMLGSDSQGMGRINEVICRTWQLADKMKSQRGRLPEESTPFGDN
ERIKRYVAKYTINPARTFGIADHIGSLEDGKLADIVVWSPAFFGIKPELILKGGFIAWGAMGDSSASLMTCEPRALRPQW
GAFGRASPALSACFVNPAAIDRGISKTLDLKKNLLPARGTRRLSKKDMLRNDACPDIRVDPQTFDVFVDGELATCEPAHE
LPLSQRYMLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-137 54
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-137 54
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 7e-137 54
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-137 54
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 5e-117 52
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 5e-117 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hden_2809 YP_003756926.1 urease subunit alpha VFG0270 Protein 5e-123 54