Gene Information

Name : Hden_2315 (Hden_2315)
Accession : YP_003756433.1
Strain : Hyphomicrobium denitrificans ATCC 51888
Genome accession: NC_014313
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2369965 - 2371485 bp
Length : 1521 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: sjp:SJA_C2-05820 aldehyde dehydrogenase

DNA sequence :
ATGCAGCACGTTGCTATGGATAAGCTCAAAGGCCGCCAGGTCATCAAGGCGCGCTACGACAACTTCATCGGCGGCAAGTG
GGTCGCCCCCGTGCGCGGGCAATATTTTACCAACGTCACGCCGATCACCGGTCAGCCCGTTTGCGAAATCGCACGCTCGA
CGGCGGAAGACATCGAGCTGGCTCTCGATGCGGCTCACAAGGTTCGTGAGTCCTGGGGCAACACCTCGCCCGCAGAGCGC
GCTCGTGTCCTCGCGAAGATCGCGACGCGCATGGAAGAGAACCTCGACGTTCTCGCGCTCGTCGAAACGATCGACAACGG
CAAGCCGATCCGCGAGACGACGCACGCCGACGTGCCGCTCGCGATCGACCACTTCCGTTATTTCGCAGGCTGCCTCCGCG
CGCAGGAAGGTTCGATCTCGGAAATCGATCACGACACCGTCGCGTATCACTTCCATGAACCGCTCGGCGTCGTCGGCCAG
ATCATCCCCTGGAACTTCCCGCTGCTGATGGCCTGCTGGAAGCTCGCCCCGGCACTCGCCGCCGGCAACTGCGTCGTGCT
GAAGCCCGCCGAGCAGACGCCGATGTCGATCATGGTTCTGATGGACATCATCGGCGATCTTCTTCCCGAAGGCGTCCTCA
ACGTCGTCAACGGCTTCGGCGTCGAAGCCGGCAAGCCGCTCGCACAGAACAAGCGCATCGCCAAGATCGCCTTCACCGGC
GAAACGACGACCGGCCGCTTGATCATGCAGTACGCGTCCGAAAACATCATTCCGTGCACGCTCGAACTTGGCGGCAAGTC
GCCGAACATCTTCTTCGCGGACGTGATGGACGCGGACGACGAATACTTCGACAAGTGCCTCGAAGGCTTCACGATGTTCG
CCCTCAACCAAGGCGAAGTCTGCACCTGCCCCAGCCGCGCGCTCGTCCAGCGTTCGATCTATGAGAAATTCATGGAGCGG
GCTCTGCAGCGCGTCGTGAAGATCAAGCAGGGTCATCCGATGGATGCCACCACGATGATCGGCGCCCAGGCTTCGAACGA
CCAGCTCGAAAAGATCTTGAGCTACGTCGAAATCGGCAAGGGCGAAGGTGCTCGCGTTCTGACGGGTGGCAAGCGTGCCG
ACCTCGGCGGCGAACTATCGTCCGGCTACTACGTCCAGCCGACGGTTCTCGAAGGCCACAACAAGATGCGCGTCTTCCAG
GAGGAAATCTTCGGACCGGTTCTCGCGGTCACGACCTTCGAAGACGATGCGGAAGCGCTCGCGATCGCCAACGACACGCT
CTACGGCCTGGGTTCGGGCGTGTGGACGCGTAACGGCACGCGCGCCTATCGCATGGGTCGCGCCATCCAGGCCGGCCGCG
TGTGGACGAACTGCTATCACGCCTATCCGGCGCACGCCGCGTTCGGTGGCTACAAGATGTCGGGCATCGGCCGTGAAACG
CACAAGATGATGCTCGATCATTATCAGCAGACGAAGAACCTGCTCGTCAGCTACAGCCCGAAGGCGCTCGGCTTCTTCTA
A

Protein sequence :
MQHVAMDKLKGRQVIKARYDNFIGGKWVAPVRGQYFTNVTPITGQPVCEIARSTAEDIELALDAAHKVRESWGNTSPAER
ARVLAKIATRMEENLDVLALVETIDNGKPIRETTHADVPLAIDHFRYFAGCLRAQEGSISEIDHDTVAYHFHEPLGVVGQ
IIPWNFPLLMACWKLAPALAAGNCVVLKPAEQTPMSIMVLMDIIGDLLPEGVLNVVNGFGVEAGKPLAQNKRIAKIAFTG
ETTTGRLIMQYASENIIPCTLELGGKSPNIFFADVMDADDEYFDKCLEGFTMFALNQGEVCTCPSRALVQRSIYEKFMER
ALQRVVKIKQGHPMDATTMIGAQASNDQLEKILSYVEIGKGEGARVLTGGKRADLGGELSSGYYVQPTVLEGHNKMRVFQ
EEIFGPVLAVTTFEDDAEALAIANDTLYGLGSGVWTRNGTRAYRMGRAIQAGRVWTNCYHAYPAHAAFGGYKMSGIGRET
HKMMLDHYQQTKNLLVSYSPKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-153 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-158 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-158 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-158 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-157 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hden_2315 YP_003756433.1 aldehyde dehydrogenase VFG0082 Protein 3e-153 63