Gene Information

Name : ldhA (RPSI07_0354)
Accession : YP_003751041.1
Strain : Ralstonia solanacearum PSI07
Genome accession: NC_014311
Putative virulence/resistance : Resistance
Product : fermentative D-lactate dehydrogenase, NAD-dependent
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : 1.1.1.28
Position : 342380 - 343366 bp
Length : 987 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 4297266, 9025293; Product type e : enzyme

DNA sequence :
ATGCGCATCCTCTTCTTCAGCAGCCACCGTTACGACGAAGACAGCTTCCGCGCCGCGCAGGCGCGCAGCGGCCACGGCTT
CGAACTGGTCTTCCAGCGCGCCCACCTGGACGTGCACACCGCGCCGCTGGCCGCCAGCTTCGAGGTGGTCTGCCCGTTCG
TCAACGACTGCCTCGATGCCGACGTGCTCGCCGTGCTGGCCGCCGGCGGCACCCGGCTGATCGCGCTGCGCTCGGCTGGC
TTCAACCATGTCGACCTGGCCGCGGCACAGCGGCTGGGGCTGACGGTGGCGCGGGTGCCGGCGTATTCGCCGCATGCGGT
GGCCGAGCACGCGGTCGGCATGATCCTCACGCTCAACCGGCGCCTGCACCGCGCCTGCAACCGCACCCGCGAGGGCGACT
TCTCGCTCGACGGGCTGCTCGGCTTCGACCTGGCCGGCAAGACCGTCGGCGTGGTCGGCACCGGGCAGATCGGGCAGGTG
TTCGCGCGCATCATGGCCGGCTTCGGCTGCCGGCTGCTGGCGTTTGATCCGTTTCCGCAGGCGGCACTGGGCGTGACCTA
CGTGCCGCTGCCGACTTTGCTGGCGCAGTCCGACATCGTCAGCCTGCACTGCCCGCTCAATGCCGACACGCACCACCTGA
TCGACGCCCGCGCGCTCGCCAGCATGAAGATGGGCGCCATGCTGATCAACACCAGCCGCGGCGGGCTGATCGACAGCCCC
GCGCTGATCGACGCGCTCAAATCCGGCCAGCTTGGCCACCTCGGGCTGGACGTCTATGAGGAAGAGGCCGACCTGTTCTT
CGAAGACCGCTCCGCCGACGTGCTGCAGGACGACGTGCTGGCGCGCCTGCTGACCTTTCCCAACGTCATCGTGACCGCGC
ACCAGGCGTTCTTCACGCGCGAGGCGCTGGCGGGCATCGCCGACACCACGCTCGCCAACGCGGCGGCATGGGCAGCCGGC
GCGCCCGCGAATGTGGTGAACGCTTAA

Protein sequence :
MRILFFSSHRYDEDSFRAAQARSGHGFELVFQRAHLDVHTAPLAASFEVVCPFVNDCLDADVLAVLAAGGTRLIALRSAG
FNHVDLAAAQRLGLTVARVPAYSPHAVAEHAVGMILTLNRRLHRACNRTREGDFSLDGLLGFDLAGKTVGVVGTGQIGQV
FARIMAGFGCRLLAFDPFPQAALGVTYVPLPTLLAQSDIVSLHCPLNADTHHLIDARALASMKMGAMLINTSRGGLIDSP
ALIDALKSGQLGHLGLDVYEEEADLFFEDRSADVLQDDVLARLLTFPNVIVTAHQAFFTREALAGIADTTLANAAAWAAG
APANVVNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-31 46
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 5e-31 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldhA YP_003751041.1 fermentative D-lactate dehydrogenase, NAD-dependent AF310956.2.orf4.gene Protein 2e-31 45
ldhA YP_003751041.1 fermentative D-lactate dehydrogenase, NAD-dependent U35369.1.gene5.p01 Protein 2e-31 45
ldhA YP_003751041.1 fermentative D-lactate dehydrogenase, NAD-dependent NC_005054.2598279.p0 Protein 7e-31 44
ldhA YP_003751041.1 fermentative D-lactate dehydrogenase, NAD-dependent NC_014475.1.orf2.gen Protein 7e-31 44
ldhA YP_003751041.1 fermentative D-lactate dehydrogenase, NAD-dependent AF155139.2.orf4.gene Protein 2e-29 43