Gene Information

Name : hrcN (RPSI07_mp0817)
Accession : YP_003749790.1
Strain :
Genome accession: NC_014310
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 995324 - 996643 bp
Length : 1320 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15345390, 19114489; Product type e : enzyme

DNA sequence :
ATGACCCATCTCGCGCTGCTCGAGTCCCTGGAGAACGCGGCCCGGACCACGCCGCTCATCCGCCGCTTCGGCAAGGTGGT
TGAAGTCACCGGCACGCTGCTGCGCGTGGGTGGTGTCGATGTCAGGCTGGGAGAACTGTGCACCCTCACCGAGCCGGACG
GCACCGTGATGCAGGAAGGCGAGGTCGTTGGCTTCAGCGAGCACTTCGCCCTGGTGGCGCCGTTCGGCGGCGTGACTGGC
CTGTCGCGCTCCACGCGGGTGGTGCCCAGTGGCCGCGCGCTGTCGGTCGGTATCGGGCCGGGCCTGCTCGGGCGCGTGCT
GGACGGGCTCGGCCGGCCGGCCGACGGCGGACCGCCGCTGGAGGTGGTGGACTACGTCCCGGTGTTCGCCAATGCGCCGG
ACCCGATGACGCGGCGGCTGGTGGAGCAGCCGCTGGCCACCGGCGTGCGCGTGATCGACGGGCTGGCCACACTGGCCGAA
GGCCAGCGCATGGGCATCTTCGCACCGGCCGGCGTGGGCAAGAGTACGCTGATGGGCATGTTCGCGCGCGGCACGGACTG
CGATGTCAACGTGATCGTGCTGATCGGCGAGCGCGGCCGCGAAGTGCGCGAGTTCATCGAGCAGATCCTGGGCGAGGAGG
GCATGCGCCGCTCCGTGGTGGTGTGCGCGACGTCGGACCGCTCCGCCGTGGAGCGCGCCAAGGCCGCGTACGTCGGCACC
GCCGTGGCCGAGTACTTCCGCGACCAGGGCCTGCGCGTGCTGCTGATGATGGATTCGCTCACGCGCTTCGCGCGCGCCCA
GCGCGAGATCGGCCTGGCCGCCGGCGAGCCGCCCACGCGGCGCGGCTTTCCGCCTTCGGTGTTCGCGGAGCTGCCGCGCC
TGCTGGAGCGCGCCGGCATGAGTGCCGCCGGCTCCATCACCGCGCTCTACACGGTGCTGGCCGAAGACGAGTCGGGCAAC
GATCCGGTGGCCGAAGAAGTGCGCGGCATCCTGGACGGCCATTTGATCCTGTCGCGCGACATCGCCGCGCGCAACCGCTA
TCCGGCCATCGACATCCTGAACAGCCTGAGCCGGGTGATGACGCAGGTGATGCCGCGCGAGCACTGCGACGCGGCCGGGC
GCATGCGCCAGCTGCTGGCCAAGTACAACGAGGTCGAGACGCTGCTGCAGATGGGCGAGTACAAGGAGGGCAGCGATCCG
GTGGCGGACGCCGCGGTGCAGTGGAACGACTGGATGGAATCCTTCCTGCGCCAGCGTACCGACGAGTGGTGCAGCCCCGA
CGAGACCCGACGGCTGCTTGACGACATCGCGCAGTCATGA

Protein sequence :
MTHLALLESLENAARTTPLIRRFGKVVEVTGTLLRVGGVDVRLGELCTLTEPDGTVMQEGEVVGFSEHFALVAPFGGVTG
LSRSTRVVPSGRALSVGIGPGLLGRVLDGLGRPADGGPPLEVVDYVPVFANAPDPMTRRLVEQPLATGVRVIDGLATLAE
GQRMGIFAPAGVGKSTLMGMFARGTDCDVNVIVLIGERGREVREFIEQILGEEGMRRSVVVCATSDRSAVERAKAAYVGT
AVAEYFRDQGLRVLLMMDSLTRFARAQREIGLAAGEPPTRRGFPPSVFAELPRLLERAGMSAAGSITALYTVLAEDESGN
DPVAEEVRGILDGHLILSRDIAARNRYPAIDILNSLSRVMTQVMPREHCDAAGRMRQLLAKYNEVETLLQMGEYKEGSDP
VADAAVQWNDWMESFLRQRTDEWCSPDETRRLLDDIAQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-137 71
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-137 71
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-140 70
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-140 70
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-140 70
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-140 70
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-140 70
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-141 70
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-140 70
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-104 60
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-77 55
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-77 55
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 9e-84 54
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-81 53
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-82 53
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-80 52
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-79 52
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-79 52
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-82 51
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-82 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-78 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-78 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-78 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-78 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-78 50
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-87 50
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 9e-82 49
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 7e-82 49
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-82 49
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-82 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-76 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-76 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-76 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-76 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-76 47
escN AAC38383.1 EscN Virulence LEE Protein 7e-77 46
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-69 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-69 45
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-69 45
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-69 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-67 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 7e-65 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hrcN YP_003749790.1 type III secretion system ATPase VFG0192 Protein 3e-105 62
hrcN YP_003749790.1 type III secretion system ATPase VFG0390 Protein 3e-106 59
hrcN YP_003749790.1 type III secretion system ATPase VFG0048 Protein 4e-110 58
hrcN YP_003749790.1 type III secretion system ATPase VFG2144 Protein 1e-94 52
hrcN YP_003749790.1 type III secretion system ATPase VFG0515 Protein 1e-78 50
hrcN YP_003749790.1 type III secretion system ATPase VFG1008 Protein 1e-70 47
hrcN YP_003749790.1 type III secretion system ATPase VFG0812 Protein 1e-76 47
hrcN YP_003749790.1 type III secretion system ATPase VFG2459 Protein 1e-74 47
hrcN YP_003749790.1 type III secretion system ATPase VFG1254 Protein 6e-78 46
hrcN YP_003749790.1 type III secretion system ATPase VFG0730 Protein 4e-77 46
hrcN YP_003749790.1 type III secretion system ATPase VFG0555 Protein 1e-69 45
hrcN YP_003749790.1 type III secretion system ATPase VFG2499 Protein 1e-71 45
hrcN YP_003749790.1 type III secretion system ATPase VFG1778 Protein 1e-69 44
hrcN YP_003749790.1 type III secretion system ATPase VFG2331 Protein 2e-73 43