Gene Information

Name : clpB (RPSI07_mp0662)
Accession : YP_003749645.1
Strain :
Genome accession: NC_014310
Putative virulence/resistance : Virulence
Product : Chaperone clpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 811977 - 814694 bp
Length : 2718 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10986262, 16038902, 16289019; Product type f : factor

DNA sequence :
ATGGCCACCCCACTCAAGACCTTGATCGCCAAGCTGAACGCGACCAGCCGGCAGGCTGCCGAGCGCGCGGCCTCGCTGTG
CATGGCGCGCGGCCACTATGAAGTCGACCTGGAGCACCTGTTCCTGGCGCTGCTCGAAAACCGCCGCAGCGACTTCGCCG
TCGCCGCCCGCGCCAGCGGCATCGATCTGGCGGCGCTGCAGCGCGACCTGGAAGCCGAGATCGCGCGCTTCCAGACCGGC
AACACGCGCACGCCGGCGTTCTCGCCGTATCTGCCCAAGCTGTTCGAGCATGCGTGGCTGATCGCCTCGTTGGATTCGCA
GATCACGCGCATCCGCTCGGGCCACCTGCTGCTCGCGCTGCTGACCGAGCCCAGCCTGGCCGCGCTGGCCGAGCGCGGCT
CGCGGCTGTTCGGCCGCTTCGAGGTGGAGCGGCTCAAGCACGAATTCGAGCGCATGACCGCCGGCTCGGACGAGCAGGAA
CAGGCCGTCGATTTCGTCGACGGTACGGCCGCCCACTCGGAAGACGGCCGCACCGCGCCCGCCGCCGCGCTGACCTCGAC
GCCGGCACTCGACCAGTTCACCGTGGACCTGACGCAGGCCGCCCGCGAAGGCCGCATCGACCCGGTGATCGGGCGCGACG
CCGAGATCCGCCAGGTGGTGGACATCCTGATGCGCCGGCGCCAGAACAACCCCATCCTGACCGGCGAGGCCGGTGTCGGC
AAGACGGCGGTGGTGGAGGGCCTTGCGCTGCGCGTGGCCGCCAACGACGTGCCGCCGCCGCTGCAGGGCGTCACGCTGCG
CACGCTCGACATGGGCCTGCTGCAGGCCGGCGCGAGCGTGAAGGGCGAGTTCGAGAACCGCCTGAAGAACGTGATCGACG
AGGTCAAGAAGAGCCCCAAGCCGATCATCCTGTTCATCGACGAGGCGCACACCATCATCGGTGCGGGCGGGCAGGCCGGG
CAGAACGATGCGGCCAACCTGCTCAAGCCGGCGCTGGCGCGCGGCGAGCTGCGCACCATCGCCGCGACCACGTGGAGCGA
GTACAAGAAGTATTTCGAAAAGGATGCGGCCCTCGCGCGCCGCTTCCAGGTCGTCAAGGTCGAAGAGCCCAGCGAGCCGC
TGGCCGCGTCCATGTTGCGCGGCATGGCGCCGCTGATGGAGCGCCACTTCGGCGTGCGCGTGCTGGACGAGGCCATCACC
GAGGCCGTGCGCCTGTCGCATCGCTACATCAGCGGGCGCCAGTTGCCGGACAAGGCTGTGAGCGTGCTGGATACGGCGTG
CGCCAAGGTGGCGCTGGGCCAGAGCGCCACGCCCGGTGCCATCGAGGACGACCAGAAAGCGCTGGAGCGCCTGCTGGGCG
AGATCACCGCGCTGCAGCGCGAGCAGAGCGCCGGCGCGGCGCACGATGCCCGCCTGGAAGCGCTGCAGGCCAAGCGCGCT
GAGCTGGACCAGCGCATCGCGCAAAACACCGAGCGCCTGGCCCAGGAGCGCGCGCTGGTGGTGCGCATCCAGGCCCTGCG
CGAGGCGCGCGAAGGCGGCACATTGGAAGCCGGCGCGCAGGACGCCGAGCCGGTGGCGGCCAACAGCGATGTGGTTGCGA
TGTCGCCCAAGCGCGCCCGCGCCGCCGACGAGCCGGACGAGCTCGCCACGCTGCTGGCCGAGCTGCGCGCGTTGCAGGGC
GAAACGCCCATGGTGCCGCTCCAGGTGGACGGCCACGTCGTGTCGGAGATCGTCTCCGCCTGGACCGGCATTCCCCTGGG
CCGCATGGTCAAGGACGAACTGCGCACCGTGCTGAACCTCAAGCCGCTGCTGGCCGCCCGCGTGATCGGCCAGGACCACG
CGCTGGATGCCATCGCCCAGCGCGTGCGCACTGCCTCGGCCAACCTGGAAGACCCGAACAAGCCGCGCGGCGTGTTCCTG
TTCGCCGGCCCGTCGGGCGTGGGCAAGACCGAGACGGCGCTGGCGCTGGCCGACATCCTCTATGGCGGCGAGCGCAAGCT
CATCACCATCAACATGAGCGAGTACCAGGAAGCACACAGCGTCTCGGGCCTCAAGGGCTCGCCGCCGGGCTACGTGGGCT
ACGGCGAGGGCGGCGTGCTGACCGAGGCGGTGCGCCGCAATCCGTACAGCGTGGTGCTGCTGGACGAAGTCGAGAAAGCC
CACCCCGACGTGCTGGAGATGTTCTTCCAGGTGTTCGACAAGGGCGAGATGGACGACGCCGAAGGCCGCCCCATCGACTT
CCGCAACACCATCATCATCCTGACCTCGAACGTGGGCTCGTCGGCCATCATGCAGGCCTGCCTGAACAAGCCCACCGAAG
CGCTGCCCGACGCCGACGCCCTGGCCGAGGCGCTGCGGCCGGTGCTGTACAAGGCCTTCAAGCCGGCCTTCCTGGGGCGG
ACCAAGGTGGTGCCGTATTACCCGATTGCCGACGACGTGCTGGCCGAGATCATCACGCTCAAGCTCGGCCGCATCCGCGA
CCGCGTGGCCGCCAACCACAAGGCGGCGTTCCAGTGGGACACCGCGCTGGTGGAATCCGTGCTGGCCCGCTGCACTGAGG
TGGACGCGGGCGCGCGCGCGGTCGACCACATCCTCAACGGCACGCTGCTGCCCGAGATCGCCGAAGCGGTGCTCACGCGC
ATGGCCGAGGGCGGCAGCGTCGAGAAGATCAAGATCAGCGTCGGCAAGACCGGCGAGTTCAAGTACCGCATCAACTGA

Protein sequence :
MATPLKTLIAKLNATSRQAAERAASLCMARGHYEVDLEHLFLALLENRRSDFAVAARASGIDLAALQRDLEAEIARFQTG
NTRTPAFSPYLPKLFEHAWLIASLDSQITRIRSGHLLLALLTEPSLAALAERGSRLFGRFEVERLKHEFERMTAGSDEQE
QAVDFVDGTAAHSEDGRTAPAAALTSTPALDQFTVDLTQAAREGRIDPVIGRDAEIRQVVDILMRRRQNNPILTGEAGVG
KTAVVEGLALRVAANDVPPPLQGVTLRTLDMGLLQAGASVKGEFENRLKNVIDEVKKSPKPIILFIDEAHTIIGAGGQAG
QNDAANLLKPALARGELRTIAATTWSEYKKYFEKDAALARRFQVVKVEEPSEPLAASMLRGMAPLMERHFGVRVLDEAIT
EAVRLSHRYISGRQLPDKAVSVLDTACAKVALGQSATPGAIEDDQKALERLLGEITALQREQSAGAAHDARLEALQAKRA
ELDQRIAQNTERLAQERALVVRIQALREAREGGTLEAGAQDAEPVAANSDVVAMSPKRARAADEPDELATLLAELRALQG
ETPMVPLQVDGHVVSEIVSAWTGIPLGRMVKDELRTVLNLKPLLAARVIGQDHALDAIAQRVRTASANLEDPNKPRGVFL
FAGPSGVGKTETALALADILYGGERKLITINMSEYQEAHSVSGLKGSPPGYVGYGEGGVLTEAVRRNPYSVVLLDEVEKA
HPDVLEMFFQVFDKGEMDDAEGRPIDFRNTIIILTSNVGSSAIMQACLNKPTEALPDADALAEALRPVLYKAFKPAFLGR
TKVVPYYPIADDVLAEIITLKLGRIRDRVAANHKAAFQWDTALVESVLARCTEVDAGARAVDHILNGTLLPEIAEAVLTR
MAEGGSVEKIKISVGKTGEFKYRIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-145 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-138 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-139 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003749645.1 Chaperone clpB VFG2076 Protein 0.0 52
clpB YP_003749645.1 Chaperone clpB VFG2084 Protein 5e-148 46