Gene Information

Name : topB (EbC_pEb10200720)
Accession : YP_003739129.1
Strain :
Genome accession: NC_014304
Putative virulence/resistance : Unknown
Product : DNA topoisomerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 62929 - 64995 bp
Length : 2067 bp
Strand : -
Note : silverDB:pEb10200125

DNA sequence :
ATGCAGCTTTATCTATGTGAAAAACCCTCTCAGGCTAAAGATATTGCCCGCGTGCTGGGTGTGAGCCAGCGCGGGCAGGG
ATGTATTAACGGCGGTAACATCACGGTGACGTGGGCTGTGGGGCATTTGCTTGAAACGGCCACGCCTGAAATTTACGGCG
AGCAGTTTGGCCGTCCGTGGAGAGCGGAGGTGCTGCCAATTATCCCGGACCGCTGGCAAATGACCGTAAAAAAAGACACT
GCCGACCAGTTTGCCGTCATCAAAAAGCTTCTAAAGCAGGCCAGTGAAGTGGTGATCGCGACCGATGCCGATCGTGAAGG
TGAAGTGATCGCGCGCGAGCTGATGGAGTATTGCAATTACAGAGGTGCCGTCCGCCGATTGTGGCTTTCCGCGCTGGACG
AAGCCAGTATCAAAAAAGCCCTCGGTGAAATGTTGCCGGGTGATAAGACTGAAATGCTCTATCAGGCCGGTGTCGGTCGA
TCGCGGGCAGACTGGCTTATCGGGATGAACCTGACGCGGCTTTATACCCTGAAAGCGGGTGAAGCCGGAGTATCAGAGGT
GTTTTCCGTGGGGCGCGTGCAGACGCCCACGCTCGCTATAGTGGTTAACCGCGATCTTGAGATTGCGGGCTTCACACCGA
AGCCGTGGTGGAAGGTTAGAGCACAGCTGCAAAAAGACGATGTTTCATTTGAGGCCGAATGGGTTGCTGCGGCGCAATAC
TGCGACGATGAAAAGCGGTGTGTTAACCATCCGATTGCCCAGGCTGTTCAGCAGCTCTGCCAGAAAGCTGGCAGCGGCAG
CGTGATCTCCGTTGAGAAAAAGCGCGATAAAACGCCGGCACCGCTGTGTTTTACTCTCGGCACGCTGATGGAAGTCTGCA
ACAAGAAATGGGGTTTTGGGGCTAATGAGGTGCTCTCAATAGCCCAGTCGCTGTATGAAACGCATAAGGCGACGACCTAT
CCGCGGACAGACTGCGGTTATCTGCCCGTTTCGATGCGCGAAGAGGTCAGGGACGTGCTCCAAGCCATACAGCACTCCGA
TCCGTCTATCACCCCCGAGCTTGCCCGTCTTGATACCGCATTTACCTCGCGCGTCTGGAACGACAAGAAAATTACCGCGC
ACCACGCGATTATCCCGACTCGACAGCCATTCGAAATAGCAAAGCTGAACGCGAAAGAGCTCAAAGTCTACTCTCTTATC
CGGCTGCACTATCTGGCCCAGTTTATGCCGCTGCAGGAATCTGATGTGACGGATGCCACCTTCAACATTGGGAATCAGCT
TTTCCGCACGCGCGGGCGCGTGATGATTCATGCCGGGTGGAAATCACTCTTCAGCGGCCAATTGTCCGAAGAGGGGGAAG
AAGATAAGGAGTCCGCCGCCCAGCTGCCTGCGCTGGAGCAGGGGAGCGTCTGCAGCGTCACCGGTGCCGACGTCAAAGAT
AATATGACCAAAGCGCCGCCGCATCATACGGAAGGAACGCTTATTGCCGCCATGAAAAACGCGGCCAGCCTGGTCACGGA
TCCTCAGCTCAAGAAGGTGCTGCGCGATAACGCAGGACTGGGAACGGAAGCGACGCGCAGCGGCGTACTGGAAACGCTGT
TTAAACGGGGTTTCTTGGAGAAAAAGGGCAAATTTATCCAGGCCACTCAGATGGCGCGGGAACTTATCGCGGCATTGCCT
GAAACGCTGACCAGCCCGGGCATGACAGCCCTTTGGGAGCAGGCGCTGGATGATATTGCCCAAGGCAAAAGCGGGCTCAG
TGATTTTATGCAAAAGCAAACACAGTGGACCCGGCATCTTATTGAAAAAGGGCGTGTCGCTGCCTTTAAAATTACGGTAC
CGGTCGGACCTTCCTGTCCTAAGTGCGGCGGACCGACTCAACAGCGCAAGAATAAAGAGGATAAGTTCTGGGGCTGCATG
AAGTTTCCGGACTGTAAGGGGATCGTTGGTGAGACGAACCGTAAAACCCGACGTCAGGCGGCGGGGAAATCCCGGGGGGG
TGGCAAAGCGAAGAGAGGCTCCGCGTCGGTACCGGCGACCATTCAGCTGCAAAGTCAGAAAGGTTGA

Protein sequence :
MQLYLCEKPSQAKDIARVLGVSQRGQGCINGGNITVTWAVGHLLETATPEIYGEQFGRPWRAEVLPIIPDRWQMTVKKDT
ADQFAVIKKLLKQASEVVIATDADREGEVIARELMEYCNYRGAVRRLWLSALDEASIKKALGEMLPGDKTEMLYQAGVGR
SRADWLIGMNLTRLYTLKAGEAGVSEVFSVGRVQTPTLAIVVNRDLEIAGFTPKPWWKVRAQLQKDDVSFEAEWVAAAQY
CDDEKRCVNHPIAQAVQQLCQKAGSGSVISVEKKRDKTPAPLCFTLGTLMEVCNKKWGFGANEVLSIAQSLYETHKATTY
PRTDCGYLPVSMREEVRDVLQAIQHSDPSITPELARLDTAFTSRVWNDKKITAHHAIIPTRQPFEIAKLNAKELKVYSLI
RLHYLAQFMPLQESDVTDATFNIGNQLFRTRGRVMIHAGWKSLFSGQLSEEGEEDKESAAQLPALEQGSVCSVTGADVKD
NMTKAPPHHTEGTLIAAMKNAASLVTDPQLKKVLRDNAGLGTEATRSGVLETLFKRGFLEKKGKFIQATQMARELIAALP
ETLTSPGMTALWEQALDDIAQGKSGLSDFMQKQTQWTRHLIEKGRVAAFKITVPVGPSCPKCGGPTQQRKNKEDKFWGCM
KFPDCKGIVGETNRKTRRQAAGKSRGGGKAKRGSASVPATIQLQSQKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 59
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 59
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 59
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 56
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 9e-170 52
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 6e-161 51
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 3e-168 50
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-150 48
topB AAW83109.1 TopB Not tested GGI Protein 6e-124 42