Gene Information

Name : cagY (HPB8_716)
Accession : YP_003728737.1
Strain : Helicobacter pylori B8
Genome accession: NC_014256
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein Y
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG2948
EC number : -
Position : 690069 - 695534 bp
Length : 5466 bp
Strand : +
Note : Bacterial conjugation TrbI-like protein

DNA sequence :
ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAATCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGC
AACAGAAGCCAATCATTTTGAAGATTCTTCAAAAGAATCCAAAGAAAGCTCAGATCATCATCTTAACAACCCTACAGAAA
CTAAAACCAATTTTGATGGAGACAAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGTGGTGATGAAACTTCAGAATCT
AGCAATGGCAGTCTAGCAGACAAGTTATTCAAAAAAGCCAGAAAATTAGTTGATAATAAAAGACTTTTCACTCAGCAAAA
GAATTTAGATGAAGAAACCCAAGAACTGAACGAAGAAGACGATCAAGAAAATAATGGGTATCAAGAAGAAACTCAAACGG
GCTTAATTGATGATGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCAACAGAGATC
AATCACTTTGAAGATTCTTCAAAAGAATCCAAAGAAAGCTCAGATCCTTATCTTGATAACCCCACAGAAACTAAAACCAA
TTTTGATGAAGACAAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGTGGTGATGAAACTTCAGAATCTAGCAATGGCA
GTCTAGCAGACAAGTTATTCAAAAAAGCCAGAAAATTAGTTGATAATAAAAGACTTTTCACTCAGCAAAAGAATTTAGAT
GAAGAAACCCAAGAACTGAACGAAGAAGACGATCAAGAAAATAATGGGTATCAAGAAGAAACTCAAACGGGCTTAATTGA
TGATGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCAACAGAGATCAATCACTTTG
AAGATTCTTCAAAAGAATCCAAAGAAAGCTCAGATCCTTATCTTGATAACCCCACAGAAACTAAAACCAATTTTGATGAA
GACAAGTCAGAAGAAATAACTAACGACTCTAACGATCAAGAAATTATCAAAGGAAGCAAAAAGAAATATATTATTGGTGG
CATTGTAGTCGCTGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTCATGCCTTTGGAAGATAAAA
GCTCTCGTTTTAGCAAAGACAGGAATCTTTATGTTAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAA
GAACGGAATGAAAAAGGCAATATGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTT
AAATATTGCAGAAATTGAGGACAAAAACCCGTTGAGAGCCTTTTATGAATGTATTAGTAATGGTGGCAACTATGAAGAAT
GTTTGAAGCTTATCAAAGACAAAAAACTTCAAGATCAGATGAAAAAGACTCTAGAGGCTTATAATGACTGCATCAAAAAT
GCCAAAACTGAAGAAGAAAGGATCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACA
AAAAGTTCAAGTGGCGCTAGATTGTTTGAAAAACGCTAAAACTGATGAAGAACGGAAAGAGTGCCTAAAACTCATAAATG
ACCCTGAGATTAGAGAGAAATTCCGTAAGGAATTAGAGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAAC
GCCAAAACAGAAGCTGAGAAAAACGAATGCTTGAAAGGCTTGTCTAAAGAAGCTATAGAAAGATTGAAACAGCAAGCGCT
AGATTGTTTGAAAAACGCTAAAACTGATGAAGAACGAAACGAGTGCTTGAAAAATATTCCCCAAGACTTGCAAAAAGAAC
TACTAGCTGATATGAGCGTCAAGGCTTACAAGGATTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAG
AAATTACTCACGCCTGAAGCGAGGAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAACTGATGAAGA
ACGAAAAAAATGTTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGCGTTAAAGCTTATAAAG
ATTGCGTATCTCAAGCCAAAAACGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTA
GAAGAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCCGAGAAAAAAGAATG
CGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCG
TATCTCAAGCCAAAACTGAAGCCGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAGAAAAAAGTTAGAAGAA
GCTAAAAAAAGCGTTAAAGCTTATAAAGATTGCGTATCTCAAGCCAAAAACGAAGATGAGAAAAAAGAATGCGAGAAATT
GCTCACCCCTGAAGCGAGAAAACTTTTAGAGCAACAAGCGTTAGATTGTTTGAAAAATGCTAAAACCGATGAAGAACGAA
AAAAGTGTTTGAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTTTTAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGC
GTATCTCAAGCCAAAAACGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGAAAACTCTTAGAAGA
GGCTAAAGAGAGCATTAAAGCTTATAAAGACTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAAT
TGCTCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAA
GCCAAAACTGAAGCCGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCTAAAGA
GAGCCTTAAAGCTTATAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTGCTCACCC
CTGAAGCGAAAAAACTTTTAGAACAACAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGATAAAAAAAGGTGT
GTCAAAGATCTCCCTAAAGACCTGCAGAAAAAGGTTTTAGCTAAAGAGAGCGTTAAAGCTTATAAAGACTGCGTATCAAG
AGCTAGGAATGAAAAAGAGAAAAAGGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCTAAAG
AGAGTCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGCGAGAAACTACTCACG
CCTGAAGCGAGGAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAAC
TGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAGTTCTTAGCGAAGCAAGTGCTAAATTGTT
TGGAAAAAGCTGGAAATGAAGAAGAAAGAAAAGCATGTCTTAAAAATCTCCCTAAAGACTTACAGGAAAATGTTTTAGCT
AAAGAGAGTCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGCGAGAAATTACT
CACCCCTGAAGCGAGAAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGACTGCGTATCAAGAGCTA
GGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGGAAATTTTTAGCGAAAGAACTCCAACAA
AAAGATAAAGCGATCAAAGATTGCTTGAAAAACGCCGATCCTAACGACAGAGCGGCTATCATGAAGTGTTTGGATGGTTT
GAGCGATGAAGAGAAGCTCAAATACCTGCAAGAAGCTAGAGAAAAGGCTGTCTTGGATTGTTTGAAAACGGCTAGGACCG
ATGAAGAAAAAAGGAAATGCCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAGGACACAAAGCAAACAA
AATCAATTGAGTAAAACAGAAAGATTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGATCAACAAGC
CATAGAGCAATGTTTAGAGGGCTTGAGCGATAGTGAAAGGGCGCTAATTCTAGGAATTAAACGACAAGCTGATGAAGTGG
ATCGGATTTATAGCGATCTAAGAAACCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCGTTGTTGCCAATGGAT
TTCAAAAATGGCGGCGATATTGCCACTATTAACGCCACTAATGTTGATGCGGACAAAATAGCTAGCGATAATCCTATTTA
TGCTTCCATAGAGCCCGACATTACCAAACAATACGAAACAGAAAAAACCATTAAGGATAAGAATTTAGAAGCTAAATTAG
CTAAGGCTTTAGGTGGCAATAAAAAAGATGACGATAAAGAAAAAAGTAAAAAATCCACAGCAGAAGCTAAAGTAGAAAGC
AATAAGATAGACAAAGATGTCGCAGAAACTGCTAAGAATATCAGTGAAATCGCTCTTAAGAACAAAAAAGAAAAGAATGG
GGAATTTGTAGATGAAAATGGTAATCCCATTGATGACAAAAAGAAAGCAGAAAAACAAGATGAAACAAGCCCTGTCAAAC
AGGCCTTTATAGGCAAGAGTGATCCCACATTTGTTTTAGCGCAATACACCCCCATTGAAATCACTCTGACTTCTAAAGTA
GATGCCACTCTCACAGGTATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATCTTACTAGA
TAAAGGCACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACACCTATTATGACACGCTTAATGATAGTCTTTA
CTAAAGCCATTACGCCTGATGGTGTGATAATACCTCTAGCAAACGCTCAAGCAGCAGGCATGTTGGGTGAAGCAGGGGTA
GATGGCTATGTGAATAATCACTTTATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTCTTGCAAAC
TGCGCCTATCATAGCTCTAGATAAACTCATAGGTCTTGGCAAAGGTAGAAGTGAAAGGACACCTGAATTTAATTACGCTT
TGGGTCAAGCTATCAATGGTAGTATGCAAAGTTCAGCCCAGATGTCTAATCAAATTCTAGGGCAACTGATGAATATCCCC
CCAAGTTTTTACAAAAATGAGGGCGATAGTATTAAGATTCTCACAATGGACGATATTGATTTTAGTGGCGTGTATGATGT
TAAAATTACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACTAAAACTTTGTCTAGAGAACATGAAGAAATCA
CCACAAGCCCCAAAGGTGGCAATTAA

Protein sequence :
MNEENDKLETSKKIQQHSPQDLSNEEATEANHFEDSSKESKESSDHHLNNPTETKTNFDGDKSEETQTQMDSGGDETSES
SNGSLADKLFKKARKLVDNKRLFTQQKNLDEETQELNEEDDQENNGYQEETQTGLIDDETSKKTQQHSPQDLSNEEATEI
NHFEDSSKESKESSDPYLDNPTETKTNFDEDKSEETQTQMDSGGDETSESSNGSLADKLFKKARKLVDNKRLFTQQKNLD
EETQELNEEDDQENNGYQEETQTGLIDDETSKKTQQHSPQDLSNEEATEINHFEDSSKESKESSDPYLDNPTETKTNFDE
DKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFMPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLK
ERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKN
AKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLKLINDPEIREKFRKELELQKELQEYKDCIKN
AKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKQECE
KLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESVKAYKDCVSQAKNEAEKKECEKLLTPEAKKLL
EEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEARKKLEE
AKKSVKAYKDCVSQAKNEDEKKECEKLLTPEARKLLEQQALDCLKNAKTDEERKKCLKDLPKDLQKKVLAKESVKAYLDC
VSQAKNEAEKKECEKLLTPEARKLLEEAKESIKAYKDCVSKARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQ
AKTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRC
VKDLPKDLQKKVLAKESVKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLT
PEARKLLEQEVKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKFLAKQVLNCLEKAGNEEERKACLKNLPKDLQENVLA
KESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEARKFLAKELQQ
KDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKRTQSKQ
NQLSKTERLHQASECLDNLDDPTDQQAIEQCLEGLSDSERALILGIKRQADEVDRIYSDLRNRKTFDNMAAKGYPLLPMD
FKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEAKVES
NKIDKDVAETAKNISEIALKNKKEKNGEFVDENGNPIDDKKKAEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKV
DATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGV
DGYVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIP
PSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cagY YP_003728737.1 cag pathogenicity island protein Y Virulence cag PAI Protein 0.0 100
cagY AGC69785.1 cag pathogenicity island protein Y Virulence cag PAI Protein 0.0 95
cagY AGC69788.1 cag pathogenicity island protein Y Virulence cag PAI Protein 0.0 95
cagY AGC69787.1 cag pathogenicity island protein Y Virulence cag PAI Protein 0.0 91
HP0527 BAD13998.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 89
HP0527 BAD13915.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 87
HP0527 BAD14026.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 87
HP0527 BAD14052.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 86
HP0527 BAD13779.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 85
cagY YP_005779063.1 cag island protein Virulence cag PAI Protein 0.0 85
cag-Y AAF80198.1 Cag-Y Virulence cag PAI Protein 0.0 84
orf13/14 NP_223194.1 cag island protein Virulence cag PAI Protein 0.0 83
HP0527 BAD13970.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 81
HP0527 BAD13888.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78