Gene Information

Name : cagX (HPB8_715)
Accession : YP_003728736.1
Strain : Helicobacter pylori B8
Genome accession: NC_014256
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein X
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3504
EC number : -
Position : 688486 - 690054 bp
Length : 1569 bp
Strand : +
Note : Conjugal transfer protein TrbG/VirB9/CagX

DNA sequence :
ATGGGGCAGGCATTTTTTAAAAAAATTGTTGGCTGTTTCTGTCTTGGTTATTTATTTTTATCTAGCGCAATAGAAGCAGC
AGCACTTGACATTAAGAATTTTAATCGTGGTAGGGTGAAAGTGGTGAATAAGAAGATTGCTTATTTGGGAGATGAAAAAC
CTATTACAATTTGGACTTCATTAGACAATGTTACTGTGATCCAACTTGAAAAAGATGAAACTATTTCTTACATCACAACA
GGTTTCAATAAAGGTTGGAGTATTGTGCCTAATTCTAATCATATATTCATTCAACCTAAATCGGTAAAAAGTAATCTCAT
GTTTGAAAAAGAAGCAGTGAATTTTGCCCTAATGACAAGAGATTACCAAGAATTTTTAAAAACAAAAAAACTTATCGTAG
ATGCGCCCGACCCTAAAGAATTAGAAGAACAAAAAAAAGCTCTAGAAAAAGAAAAAGAAGCTAAAGAACAGGCGCAAAAA
GCGCAAAAAGATAAAAGAGAAAAAAGAAAAGAAGAGCGTGCAAAAAATAGAGCCAATTTAGAAAATCTCACTAACGCTAT
GAGTAACCCACAAAATTTGAGCAATAACAAAAATCTTAGCGAATTTATCAAGCAACAACGAGAAAATGAATTAGACCAAA
TGGAACGACTAGAGGACATGCAAGAACAGGCTCAAGCTAATGCGCTCAAACAAATTGAAGAACTCAACAAGAAACAAGCT
GAAGAGGCAGTTAGACAAAGAGCCAAGGATAAAATCAATATTAAGACAGATAAATCTCAAAAAAGTCCTGAGGATAACTC
CATAGAATTATCTCCTAGCGATAGCGCTTGGAGGACTAATCTTGTTGTGCGAACTAATAAAGCCTTGTATCAATTCATTT
TGAGAATAGCTCAAAAAGACAATTTTGCTTCGGCGTATCTAACAGTCAAATTAGAATACCCACAAAGACACGAAGTCTCT
AGCGTTATTGAAGAGGAGCTAAAAAAGAGAGAAGAAGCAAAGAGGCAGAAAGAATTGATTAAGCAAGAAAATCTTAACAC
CACAGCCTACATCAATAGAGTAATGATGGCGAGCAATGAACAGATTATCAACAAAGAAAAAATAAGAGAAGAAAAACAAA
AAATTATCTTAGATCAAGCAAAGGCGCTAGAGACTCAATATGTGCATAATGCCTTAAAAAGAAACCCTGTGCCTAGAAAC
TACAATTACTACCAAGCACCTGAAAAACGCTCTAAACATATTATGCCCTCTGAAATTTTTGATGATGGCACATTCACTTA
TTTTGGTTTCAAAAACATCACTCTCCAACCTGCTATTTTTGTGGTTCAACCTGATGGGAAATTGAGCATGACTGATGCTG
CCATTGATCCTAACATGACCAATTTAGGATTAAGATGGTATAGAGTTAATGAAATTGCAGAAAAATTTAAGCTCATTAAA
GACAAAGCCCTTGTAACAGTAATAAATAAAGGCTATGGGAAAAATCCATTGACAAAAAATTACAATATCAAAAACTATGG
TGAATTGGAGCGCGTGATTAAAAAGCTCCCTCTTGTCAGAGATAAATAA

Protein sequence :
MGQAFFKKIVGCFCLGYLFLSSAIEAAALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITT
GFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK
AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA
EEAVRQRAKDKINIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVS
SVIEEELKKREEAKRQKELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN
YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNLGLRWYRVNEIAEKFKLIK
DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cagX YP_003728736.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 100
cagX AGC69795.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 100
HP0528 BAD13861.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005779062.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005775731.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005774541.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13834.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13807.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13889.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13916.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03891.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD14053.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03921.1 Cag8 Virulence cag PAI Protein 0.0 99
cagX YP_005777272.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD14027.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
orf15 NP_223195.1 cag island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03952.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 NP_207324.1 cag pathogenicity island protein (cag8) Virulence cag PAI Protein 0.0 99
cag-X AAF80199.1 Cag-X Virulence cag PAI Protein 0.0 99
cag8 AAR03863.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD13944.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13780.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13971.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13999.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cagX YP_003728736.1 cag pathogenicity island protein X VFG0288 Protein 0.0 99