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Name : cagE (HPB8_699) Accession : YP_003728720.1 Strain : Helicobacter pylori B8 Genome accession: NC_014256 Putative virulence/resistance : Virulence Product : cag pathogenicity island protein E Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG3451 EC number : - Position : 671999 - 674944 bp Length : 2946 bp Strand : + Note : CAG pathogenicity island protein 23 (Protein picB), CagE, TrbE, VirB component of type IV transporter system, CagE, TrbE, VirB family, component of type IV transporter system, VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family DNA sequence : GTGGCAAGCAAACAAGCTGACGAACAAAAAAAGCTAGTCATAGAGCAAGAGGTTCAAAAGCGCCAATTTCAAAAAATAGA AGAACTTAAAGCAGACATGCAAAAGGGTGTCAATCCCTTTTTTAAAGTCTTGTTTGATGGGGGGAATAGGTTGTTTGGTT TCCCTGAAACTTTTATTTATTCCTCTATATTTATATTGTTTGTAACAATTGTATTATCTGTTATTCTTTTTCAAGCCTAT GAACCTGTTTTGATTGTAGCGATTGTTATTGTGCTTGTAGCTCTTGGATTCAAGAAAGATTACAGGCTTTATCAAAGAAT GGAGCGAGCGATGAAATTTAAAAAACCTTTTTTGTTTAAGGGCGTGAAAAACAAAGCGTTCATGAGCATTTTTTCCATGA AGCCTAGTAAAGAAATGGCTAATGACATCCACTTAAATCCAAACAGAGAAGACAGACTTGTGAGCGCTGCAAACTCCTAT CTAGCGAATAACTATGAATGTTTTTTAGATGATGGGGTGATCCTTACTAACAACTATTCTCTTTTAGGCACAATCAAATT GGGGGGCATTGATTTTTTAACCACTTCAAAAAAAGATCTCATAGAGTTACACGCTTCTATTTATAGCGTTTTTAGGAATT TTGTTACCCCTGAATTCAAATTTTATTTTCACACTATTAAAAAGAAAATCGTTATTGATGAAACCAATAGGGACTATGGT CTTATTTTTTCTAATGATTTTATGCGAGCCTATAATGAGAAGCAAAAGAGAGAAAGTTTTTATGATATTAGTTTTTATCT CACCATAGAGCAAGATTTATTAGACACTCTCAATGAACCCGTTATGAATAAAAAGCATTTTGCAGACAATAATTTTGAAG AGTTTCAAAGGATTATTAGAGCCAAGCTTGAAAACTTCAAGGATAGGATAGAGCTCATAGAAGAGCTATTGAGTAAATAC CACCCCATTAGATTAAAAGAATACACTAAAGATGGCGTTATTTACTCCAAACAATGCGAGTTTTATAATTTCCTTGTGGG AATGAATGAAGCCCCTTTTATTTGCAACAGAAAAGACTTGTATCTCAAGGAAAAAATGCATGGTGGGGTGAAAGAAGTTT ATTTTGCCAATAAGCATGGAAAAATCTTAAATGACGATTTGAGTGAAAAATATTTTAGCGCTATTGAGATTAGTGAATAC GCCCCTAAATCACAGAGCGATTTGTTTGATAAAATCAACGCTCTAGACAGCGAATTTATCTTTATGCATGCTTATTCGCC TAAAAACTCACAGGTTTTAAAGGACAAACTAGCTTTCACTTCTAGAAGAATTATTATTAGTGGAGGCTCTAAAGAGCAGG GCATGACTTTAGGTTGCTTGAGCGAATTAGTGGGTAATGGCGATATTACGCTAGGCAGTTATGGTAATTCTTTAGTGTTG TTTGCTGATAGCTTTGAAAAAATGAAACAAAGCGTTAAGGAATGTGTCTCTAGTCTTAACGCTAAAGGTTTTTTAGCCAA CGCGGCGACTTTCTCTATGGAAAATTACTTTTTTGCCAAACATTGCTCTTTTATCACGCTTCCTTTTATTTTTGATGTAA CTTCTAATAATTTTGCTGATTTTATTGCGATGAGGGCTATGAGCTTTGATGGCAATCAGGAGAATAACGCTTGGGGCAAT AGCGTCATGACACTAAAAAGCGAGATCAATTCGCCTTTTTATCTGAACTTCCACATGCCCACTGATTTTGGTTCAGCTTC AGCAGGACACACTTTGATACTTGGATCAACCGGTTCAGGTAAGACAGTGTTTATGTCAATGACCTTGAACGCTATGGGGC AATTTGTTCACAATTTTCCTGCTAATGTCAGCAAAGACAAGCAAAAGCTCACTATGGTCTATATGGATAAAGATTATGGC GCTTATGGGAATATTGTCGCAATGGGTGGGGAGTATGTCAAAATTGAGCTAGGGACAGATACAGGATTAAATCCTTTTGC TTGGGCAGCTTGTGTGCAAAAAACAAATGCAACAATGGAGCAAAAACAAACGGCTATTTCTGTTGTCAAAGAGCTTGTGA AAAACTTAGCAACCAAAAGCGATGAAAAAGATGAAAATGGCAACAGCATCTCTTTTAGCCTAGCAGATTCTAATACGCTT GCAGCGGCAGTAACCAACCTTATCACAGGAGATATGAACCTAGATTATCCCATCACTCAACTTATTAATGCTTTCGGGAA AGACCACAATGATCCTAATGGGCTTGTCGCGCGATTAGCACCTTTTTGCAAATCAACCAATGGTGAATTTCAATGGCTTT TTGATAATAAAGCAACGGATCGCTTAGATTTTTCAAAAACGATTATTGGCGTTGATGGGTCAAGTTTCTTAGACAATAAT GATGTTTCGCCCTTTATTTGTTTTTACCTTTTCGCTCGTATCCAAGAGGCAATGGATGGGCGTAGATTTGTCTTAGATAT TGATGAAGCTTGGAAATATTTAGGCGATCCAAAGGTCGCTTATTTTGTGAGAGACATGCTAAAAACTGCAAGGAAAAGAA ACGCTATTGTCAGACTTGCGACTCAAAGCATCACTGATCTTTTGGCTTGCCCTATTGCTGATACGATTAGAGAACAATGC CCTACAAAGATTTTTTTGAGAAACGATGGGGGCAATCTTTCTGATTACCAAAGATTAGCTAATGTTACAGAAAAAGAATT TGAAATCATCACTAAGGGACTAGACAGGAAAATTCTCTACAAACAAGATGGAAGCCCTAGCGTTATCGCTAGTTTTAATT TGAGAGGCATTCCTAAAGAATATTTGAAAATTTTATCCACAGATACTGTATTTGTCAAAGAAATTGACAAGATTATCCAA AACCATAGTATCATAGATAAATATCAGGCCTTGAGGCAAATGTATCAACAAATAGAGGAGTATTAA Protein sequence : MASKQADEQKKLVIEQEVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSIFILFVTIVLSVILFQAY EPVLIVAIVIVLVALGFKKDYRLYQRMERAMKFKKPFLFKGVKNKAFMSIFSMKPSKEMANDIHLNPNREDRLVSAANSY LANNYECFLDDGVILTNNYSLLGTIKLGGIDFLTTSKKDLIELHASIYSVFRNFVTPEFKFYFHTIKKKIVIDETNRDYG LIFSNDFMRAYNEKQKRESFYDISFYLTIEQDLLDTLNEPVMNKKHFADNNFEEFQRIIRAKLENFKDRIELIEELLSKY HPIRLKEYTKDGVIYSKQCEFYNFLVGMNEAPFICNRKDLYLKEKMHGGVKEVYFANKHGKILNDDLSEKYFSAIEISEY APKSQSDLFDKINALDSEFIFMHAYSPKNSQVLKDKLAFTSRRIIISGGSKEQGMTLGCLSELVGNGDITLGSYGNSLVL FADSFEKMKQSVKECVSSLNAKGFLANAATFSMENYFFAKHCSFITLPFIFDVTSNNFADFIAMRAMSFDGNQENNAWGN SVMTLKSEINSPFYLNFHMPTDFGSASAGHTLILGSTGSGKTVFMSMTLNAMGQFVHNFPANVSKDKQKLTMVYMDKDYG AYGNIVAMGGEYVKIELGTDTGLNPFAWAACVQKTNATMEQKQTAISVVKELVKNLATKSDEKDENGNSISFSLADSNTL AAAVTNLITGDMNLDYPITQLINAFGKDHNDPNGLVARLAPFCKSTNGEFQWLFDNKATDRLDFSKTIIGVDGSSFLDNN DVSPFICFYLFARIQEAMDGRRFVLDIDEAWKYLGDPKVAYFVRDMLKTARKRNAIVRLATQSITDLLACPIADTIREQC PTKIFLRNDGGNLSDYQRLANVTEKEFEIITKGLDRKILYKQDGSPSVIASFNLRGIPKEYLKILSTDTVFVKEIDKIIQ NHSIIDKYQALRQMYQQIEEY |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cagE | YP_003728720.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 100 |
| cagE | YP_005774527.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51901.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | AAF80209.1 | CagE | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51896.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD14069.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | NP_223210.1 | DNA transfer protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cag23 | AAR03906.1 | Cag23 | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51903.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51904.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51893.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51902.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13877.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51932.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51926.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51907.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51910.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51930.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51900.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51916.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | NP_207340.1 | cag pathogenicity island protein (cag23) | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD14042.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51925.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD14015.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51923.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51891.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51914.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13960.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51913.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51917.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51911.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13905.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51908.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51928.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51909.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cag23 | AAR03936.1 | Cag23 | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51920.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51922.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51899.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51895.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13823.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51897.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | YP_005777285.1 | DNA transfer protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cag23 | AAR03967.1 | Cag23 | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51924.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51927.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51905.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51892.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13850.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51894.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51929.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | YP_005775744.1 | DNA transfer protein | Not tested | cag PAI | Protein | 0.0 | 99 |
| cagE | AGC69804.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51919.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51906.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13796.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51898.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51931.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51918.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | YP_005779049.1 | DNA transfer protein | Not tested | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51912.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cag23 | AAR03878.1 | Cag23 | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13932.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| HP0544 | BAD13987.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51915.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 99 |
| cagE | BAD51921.1 | cag pathogenicity island protein E | Virulence | cag PAI | Protein | 0.0 | 98 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| cagE | YP_003728720.1 | cag pathogenicity island protein E | VFG0303 | Protein | 0.0 | 99 |
