Gene Information

Name : guaA (HPB8_461)
Accession : YP_003728482.1
Strain : Helicobacter pylori B8
Genome accession: NC_014256
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 429694 - 431220 bp
Length : 1527 bp
Strand : +
Note : [KO:K01951], synonyms: Glutamine amidotransferase, GMP synthetase, bifunctional GMP synthase/glutamine amidotransferase protein

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGGGAGAGCGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCGTAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTATACGCTAAAGACGCTTACAAGCCTAACGAGAAAATCTTTGATTTGAATGTGCCGATTTTAGGGATTTGCTACGGC
ATGCAATATTTGGTGGATTTTTTTGGGGGCGTGGTGGTTGGTGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CGCTCAAAATTCCGTGATTTTTGAAGGCGTGAAGATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAC
TGCCTAAAGGCTTTACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCGTTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGTGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATCGCGCGATTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTGCACAGGGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGAGTCCAAGCGATGTTTAAGGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGGAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAATTTTTAGCCCAAGGCACT
CTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGATTTTAAACTCATAGAGCCTTTAAGGGAGTTGTTTAAAGATGAGGTGCGCTTACTGGGTAAAGAAT
TGGGCGTTAGCCAGGATTTTTTAATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCTGTAAGGATTTTAGGCGAAGTCAGC
GAGAGTAAGATCAAACGCTTGCAAGAAGCGGATTTTATTTTTATAGAGGAACTTAAAAAAGCCAATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTGAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACTTATGAAAACGCTATTT
GCTTAAGAGCGGTAAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYTEIVPFFESVENIQKKAPKGLILSGGPASVYAKDAYKPNEKIFDLNVPILGICYG
MQYLVDFFGGVVVGANEQEFGKAVLEIAQNSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVVQSEEGGKILENFALLVCGCEKTWGMQHFAQREIARLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKGIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAVRILGEVS
ESKIKRLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-133 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-115 47