Gene Information

Name : hemC (HPB8_1326)
Accession : YP_003729347.1
Strain : Helicobacter pylori B8
Genome accession: NC_014256
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1300656 - 1301576 bp
Length : 921 bp
Strand : +
Note : [KO:K01749], synonyms: porphobilinogen deaminase, PBG, hydroxymethylbilane synthase, HMBS, pre-uroporphyrinogen synthase, (4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2- yl)methyltransferase (hydrolyzing), HMB-synthase, porphobilinogen ammonia-lyase (polym

DNA sequence : 
GTGGGAAATTTAGTGATTGGCTCTAGGGGGAGCGAATTAGCCTTATGGCAAGCGAATCACATTAAAGAACGTCTGAAAAA
AGAATGCTTTATAGAAAGCGAGATTCAAATCGTTAAAACCACAGGTGATAAGATTTTAGACGCGCCTTTAAATAAGATTG
GCGGTAAGGGGCTATTCACTAAGGAATTGGAAGAATTGCTTTTAAAGGGTGCAATTGATTTGGCGGTGCATTCTTTAAAA
GATGTGCCGGTCGTGTTTGAAAAGGGGTTAGACTTGGCATGCATCACTAAAAGGGCTGATGCGAGGGACACTTTTTTGAG
CGTGAAATTCCCTGATTTGATGAGCTTGCCTAAAGGAGCCAAGGTTGGCACGACTTCTTTAAGGCGCTCCATGCAAATCA
AACTGAAGCGCCAGGATCTAGACACAGAAAGCTTAAGGGGGAATGTCCAAACCCGTTTGAAAAAGCTTGAATGCGGAGAA
TTTGACGCTATCATTTTAGCTGAAGCCGGGTTGTGCCGCTTAAACGTTCAAGGGGCGAAATACCGCAAGGCTTTTAGTGT
AGAAGAAATGATTCCTAGCATGGGTCAGGGGGCTTTAGGGGTAGAAATGCTCAAAAACCACAAGCATTTTATTACGCTCC
AAAAACTCAACGATGAAGAAAGCGCGTTTTGCTGCCATTTAGAAAGGGAGTTTATTAAGGGGCTTAATGGGGGGTGTCAG
ATTCCTGTGGGCGTGCATGCGAATTTAATGGGCGATGAGGTTAAAATCCAAGCGGTTTTAGGCTTGCCTAATGGGAAAGA
AGTCATCACTAAAGAAAAGCAAGGGGATAAAAATAAGGCGTTTGATTTAGTGCAAGAGCTTTTAGAAGAATTTTTACAAA
GCGGGGCGAAAGAGATTTTAGAAAAGGCGCAGTTGTTTTAA

Protein sequence : 
MGNLVIGSRGSELALWQANHIKERLKKECFIESEIQIVKTTGDKILDAPLNKIGGKGLFTKELEELLLKGAIDLAVHSLK
DVPVVFEKGLDLACITKRADARDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGE
FDAIILAEAGLCRLNVQGAKYRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPVGVHANLMGDEVKIQAVLGLPNGKEVITKEKQGDKNKAFDLVQELLEEFLQSGAKEILEKAQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-43 46
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-43 46