Gene Information

Name : fliI (HPB8_124)
Accession : YP_003728145.1
Strain : Helicobacter pylori B8
Genome accession: NC_014256
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 118103 - 119407 bp
Length : 1305 bp
Strand : +
Note : [KO:K02412]

DNA sequence : 
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAACGTTTTGATCTATCGCCTCGCTACGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGGATGGTTTTAACCCATCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGCAGCGAAT
GCGTGGGAATGGTGGTAGTGGCAGAAAAAGAGCAGTTTGGTTTCACGCCCTTTAACTTTATAGAGGGGGCTAGGGCTGGC
GATAAGGTGCTGTTTTTAAAAGAGGGGTTGAATTTCCCTGTGGGCCGTAATCTTTTAGGGAGGGTGCTTAACCCTTTAGG
GCAAGTCATTGACAATAAGGGGGCGCTAGATTATGAGCGGTTAGCGCCTGTGATCACAACGCCTATAGCCCCTTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGGGTGAAGAGCATTGATGGGCTTTTGACTTGCGGTAAGGGGCAAAAACTG
GGCATTTTTGCCGGCTCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGTTGCTTAGCGCCCATTAAAGT
GATCGCTTTGATTGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACTTAAAAGGGGATTTAAGCTCTTGCG
TGTTGGTGGTCGCTACGAGCGATGATAGCCCTTTGATGCGCAAATACGGGGCCTTTTGCGCGATGAGCGTGGCGGAGTAT
TTTAAAAACCAAGGGCTAGACGTGTTATTCATCATGGATTCAGTGACTCGTTTCGCTATGGCTCAAAAAGAAATCGGTTT
GGCCTTAGGCGAACCGCCCACTTCCAAAGGCTACCCCCCATCCGCGCTTTCCTTATTGCCTCAATTAATGGAGAGGGCGG
GCAAGGAAGAAAATAAGGGGAGCATTACGGCTTTTTTTAGCGTGCTAGTAGAGGGCGATGATTTGAGCGATCCCATAGCC
GATCAAGCCAGGAGTATTTTAGATGGGCATATTGTCTTAAGCAGGGAATTGACCGATTATGGGATCTACCCGCCTATCAA
TATTTTAAACTCCGCATCAAGGGTGGCTAAAGACATCATCAGCGAGTCTCAAAACCTTTGCGCGAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAAATGCTCATTCGCATCGGCTCTTATCAAATGGGGAACGATAAAGAGCTTGATGAA
GCGATTAAGAAAAAGGCTTTAATGGAGCAATTTTTAGCGCAAGATGAAAACGCTTTGCAGCCTTTTGAACAAAGCTTTCA
GCAACTAGAAGAAATCTTAAGATAA

Protein sequence : 
MPLKSLKNRLNQRFDLSPRYGSVKKIMPNIVYADGFNPSVGDVVKIEKSDGSECVGMVVVAEKEQFGFTPFNFIEGARAG
DKVLFLKEGLNFPVGRNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQKEIGLALGEPPTSKGYPPSALSLLPQLMERAGKEENKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLCARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AIKKKALMEQFLAQDENALQPFEQSFQQLEEILR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 7e-73 50
escN AAC38383.1 EscN Virulence LEE Protein 8e-78 46
escN AAC31513.1 L0034 Virulence LEE Protein 5e-78 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 7e-78 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 5e-78 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 7e-78 46
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-76 45
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-76 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-76 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-76 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-76 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-77 45
escN AAK26715.1 EscN Virulence LEE Protein 3e-76 45
escN AAL57542.1 EscN Virulence LEE Protein 3e-76 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-54 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-54 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-81 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-81 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-81 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-81 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-79 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-81 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-79 43
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-79 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-70 43
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-70 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 9e-53 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 8e-53 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-59 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-59 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-58 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-58 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_003728145.1 flagellum-specific ATP synthase VFG0390 Protein 1e-78 52
fliI YP_003728145.1 flagellum-specific ATP synthase VFG0192 Protein 8e-77 51
fliI YP_003728145.1 flagellum-specific ATP synthase VFG0048 Protein 2e-78 50
fliI YP_003728145.1 flagellum-specific ATP synthase VFG2144 Protein 1e-77 47
fliI YP_003728145.1 flagellum-specific ATP synthase VFG0812 Protein 3e-78 46
fliI YP_003728145.1 flagellum-specific ATP synthase VFG0730 Protein 4e-78 46
fliI YP_003728145.1 flagellum-specific ATP synthase VFG1254 Protein 3e-77 45
fliI YP_003728145.1 flagellum-specific ATP synthase VFG2331 Protein 3e-71 42
fliI YP_003728145.1 flagellum-specific ATP synthase VFG1778 Protein 4e-55 42
fliI YP_003728145.1 flagellum-specific ATP synthase VFG1008 Protein 1e-59 41