Gene Information

Name : leuS (HMPREF0837_10570)
Accession : YP_003724012.1
Strain : Streptococcus pneumoniae TCH8431/19A
Genome accession: NC_014251
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 501183 - 503684 bp
Length : 2502 bp
Strand : +
Note : COG: COG0495; Pfam: PF09334,PF08264; InterPro: IPR002302

DNA sequence :
ATGAGTTTTTATAATCATAAAGAAATTGAGCCTAAGTGGCAGGGCTACTGGGCAGAACATCATACATTTAAGACAGGAAC
AGATGCATCAAAACCTAAGTTTTATGCGCTTGATATGTTCCCTTATCCGTCTGGAGCTGGTCTGCACGTAGGACACCCAG
AAGGTTATACTGCAACCGATATCCTCAGTCGTTACAAACGTGCGCAAGGCTACAATGTCCTTCACCCAATGGGTTGGGAT
GCTTTTGGTTTGCCTGCAGAGCAATACGCTATGGATACTGGTAATGACCCAGCAGAATTTACAGCGGAAAACATTGCCAA
CTTCAAACGTCAGATCAATGCGCTTGGATTTTCTTATGACTGGGATCGTGAAGTCAACACAACAGATCCAAACTACTACA
AGTGGACTCAATGGATTTTCACCAAGCTTTACGAAAAAGGCTTGGCCTATGAAGCTGAAGTGCCAGTAAACTGGGTTGAG
GAATTGGGAACTGCCATTGCCAATGAAGAAGTGCTTCCTGACGGAACTTCTGAGCGTGGAGGCTATCCAGTTGTCCGCAA
ACCAATGCGCCAATGGATGCTCAAAATCACGGCTTACGCAGAGCGCTTGCTCAATGACTTAGATGAACTAGATTGGTCAG
AGTCTATCAAGGATATGCAACGCAACTGGATTGGTAAATCAACTGGTGCCAATGTAACTTTCAAAGTAAAAGGAACAGAC
AAGGAATTTACAGTCTTTACTACTCGTCCGGACACACTTTTCGGTGCGACTTTCACTGTCTTGGCTCCTGAACATGAATT
AGTAGACGCTATCACAAGTTCAGAGCAAGCAGAAGCTGTAGCAGACTATAAACACCAAGCCAGCCTTAAGTCTGACTTGG
TTCGTACAGACCTTGCTAAGGAAAAAACTGGTGTTTGGACTGGTGCTTATGCCATCAACCCTGTCAATGGTAAGGAAATG
CCAATCTGGATTGCGGACTATGTTCTTGCTAGTTATGGAACAGGTGCGGTTATGGCTGTGCCTGCCCACGACCAACGTGA
CTGGGAATTTGCCAAACAATTTGACCTTCCAATCGTCGAAGTACTTGAAGGTGGAAATGTCGAAGAAGCTGCCTACACAG
AGGATGGCCTGCATGTCAATTCAGACTTCCTAGATGGATTGAACAAAGAAGACGCTATTGCCAAGATTGTGGCTTACTTG
GAAGAAAAAGGCTGTGGTCAGGAGAAGGTTACCTACCGTCTCCGCGACTGGCTCTTTAGCCGTCAACGTTACTGGGGTGA
ACCAATTCCAATTATTCATTGGGAAGATGGAACTTCAACAGCTGTTCCTGAAACTGAATTGCCGCTTGTCTTGCCTGTCA
CCAAGGACATCCGTCCTTCAGGTACCGGTGAAAGTCCACTAGCTAACTTGACAGACTGGCTTGAAGTGACTCGTGAAGAT
GGTGTCAAAGGTCGTCGTGAAACTAACACCATGCCACAATGGGCTGGTTCAAGCTGGTACTACCTTCGCTATATTGACCC
GCACAATACTGAGAAATTGGCTGATGAGGACCTCCTCAAACAATGGTTGCCAGTAGATATCTACGTGGGTGGTGCGGAAC
ATGCTGTACTTCACTTGCTTTATGCTCGTTTCTGGCATAAATTCCTCTATGACCTCGGTGTTGTTCCGACTAAGGAACCA
TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTACCGTGACCACCGTGGTGCTCTTGTGACAACCGACAA
GGTTGAAAAACGTGATGGTTCCTTCTTCCATGTAGAAACAGGGGAAGAGTTGGAGCAAGCGCCAGCCAAGATGTCTAAAT
CGCTCAAGAACGTTGTTAACCCAGACGATGTGGTGGAACAATACGGTGCCGATACCCTTCGTGTTTATGAAATGTTTATG
GGACCACTCGATGCTTCGATTGCTTGGTCAGAAGAAGGTTTGGAAGGAAGCCGTAAGTTCCTTGACCGAGTTTACCGTTT
GATTACAAGTAAAGAAATCCTTGCGGAAAACAATGGTGCTCTTGACAAGGCTTACAACGAAACAGTCAAAGCTGTTACTG
AGCAAATTGAGTCTCTCAAATTCAACACAGCTATTGCCCAACTTATGGTCTTTGTCAATGCTGCTAACAAGGAAGATAAG
CTTTATATTGACTATGCCAAAGGCTTTATTCAATTGATTGCACCATTTGCACCTCACTTGGCAGAAGAACTCTGGCAAAC
AGTCGCAGAAACAGGTGAGTCAATCTCTTATGTAGCTTGGCCAACTTGGGACGAAAGCAAATTGGTTGAAGATGAAATTG
AAATTGTCGTCCAAATCAAAGGAAAAGTTCGTGCCAAACTCATGGTTGCTAAAGATCTATCACGTGAAGAATTACAAGAA
ATCGCTTTAGCTGATGAAAAAGTCAAAGCAGAAATTGACGGTAAGGAAATCGTGAAAGTAATTGCGGTACCGAATAAACT
CGTTAATATCGTCGTTAAATAA

Protein sequence :
MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD
KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEM
PIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYL
EEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEP
FQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK
LYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQE
IALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 91