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Name : HMPREF0837_12207 (HMPREF0837_12207) Accession : YP_003725649.1 Strain : Streptococcus pneumoniae TCH8431/19A Genome accession: NC_014251 Putative virulence/resistance : Resistance Product : tetracycline resistance protein TetM Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0480 EC number : - Position : 2019955 - 2021889 bp Length : 1935 bp Strand : + Note : COG: COG0480; Pfam: PF00009,PF03144,PF03764,PF00679; InterPro: IPR000795 DNA sequence : ATGGAGGAAAATCACATGAAAATTATTAATATTGGAGTTTTAGCTCATGTTGATGCGGGAAAAACTACCTTAACAGAAAG CTTATTATATAACAGTGGAGCGATTACAGAATTAGGAAGCGTGGACAAAGGTACAACGAGGACGGATAATACGCTTTTAG AACGTCAGAGAGGAATTACAATTCAGACAGGAATAACCTCTTTTCAGTGGGAAAATACGAAGGTGAACATCATAGACACG CCAGGACATATGGATTTCTTAGCAGAAGTATATCGTTCATTATCAGTTTTAGATGGGGCAATTCTACTGATTTCTGCAAA AGATGGCGTACAAGCACAAACTCGTATATTATTTCATGCACTTAGGAAAATGGGGATTCCCACAATCTTTTTTATCAATA AGATTGACCAAAATGGAATTGATTTATCAACGGTTTATCAGGATATTAAAGAGAAACTTTCTGCCGAAATTGTAATCAAA CAGAAGGTAGAACTGTATCCTAATATGTGTGTGACGAACTTTACCGAATCTGAACAATGGGATACGGTAATAGAGGGAAA CGATGACCTTTTAGAGAAATATATGTCCGGTAAATCATTAGAAGCATTGGAACTCGAACAAGAGGAAAGCATAAGATTTC ATAATTGTTCCCTGTTCCCTGTTTATCACGGAAGTGCAAAAAACAATATAGGGATTGATAACCTTATAGAAGTGATTACG AATAAATTTTATTCATCAACACATCGAGGTCAGTCTGAACTTTGCGGAAAAGTTTTCAAAATTGAGTATTCGGAAAAAAG ACAGCGTCTTGCATATATACGTCTTTATAGTGGCGTACTGCATTTGCGAGATTCGGTTAGAATATCGGAAAAGGAAAAAA TAAAAATTACAGAAATGTATACTTCAATAAATGGTGAATTATGTAAAATCGATAAGGCTTATTCCGGGGAAATTGTTATT TTGCAGAATGAGTTTTTGAAGTTAAATAGTGTTCTTGGAGATACAAAGCTATTGCCACAGAGAGAGAGAATTGAAAATCC CCTCCCTCTGCTGCAAACAACTGTTGAACCGAGCAAACCTCAACAAAGGGAAATGTTACTTGATGCACTTTTAGAAATCT CCGACAGTGACCCGCTTCTGCGATATTATGTGGATTCTGCGACACATGAAATCATACTTTCTTTCTTAGGGAAAGTACAA ATGGAAGTGACTTGTGCTCTGCTGCAAGAAAAGTATCATGTGGAGATAGAAATAAAAGAGCCTACAGTCATTTATATGGA AAGACCGTTAAAAAAAGCAGAGTATACCATTCACATCGAAGTTCCACCGAATCCTTTCTGGGCTTCCATTGGTTTATCTG TATCACCGCTTCCGTTGGGAAGTGGAATGCAGTATGAGAGCTCGGTTTCTCTTGGATACTTAAATCAATCATTTCAAAAT GCAGTTATGGAAGGGATACGCTATGGCTGTGAACAAGGATTGTATGGTTGGAATGTGACGGACTGTAAAATCTGTTTTAA GTATGGCTTATACTATAGCCCTGTTAGTACCCCAGCAGATTTTCGGATGCTTGCTCCTATTGTATTGGAACAAGTCTTAA AAAAAGCTGGAACAGAATTGTTAGAGCCATATCTTAGTTTTAAAATTTATGCGCCACAGGAATATCTTTCACGAGCATAC ACCGATGCTCCTAAATATTGTGCGAACATCGTAGACACTCAATTGAAAAATAATGAGGTCATTCTTAGTGGAGAAATCCC TGCTCGGTGTATTCAAGAATATCGTAGTGATTTAACTTTCTTTACAAATGGACGTAGTGTTTGTTTAACAGAGTTAAAAG GGTACCATGTTACTACCGGTGAACCTGTTTGCCAGCCCCGTCGTCCAAATAGTCGGATAGATAAAGTACGATATATGTTC AATAAAATAACTTAG Protein sequence : MEENHMKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIIDT PGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK QKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT NKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVI LQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQ MEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQN AVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAY TDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMF NKIT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SSU05_0922 | YP_001198287.1 | translation elongation factor (GTPases) | Not tested | 89K | Protein | 0.0 | 96 |
| SSU98_0928 | YP_001200485.1 | translation elongation factor (GTPases) | Not tested | 89K | Protein | 0.0 | 96 |
| tetO | AFJ97266.1 | truncated tetracycline resistant protein | Not tested | Not named | Protein | 3e-164 | 75 |
| tet(W) | YP_005160006.1 | tetracycline resistance protein | Not tested | Not named | Protein | 0.0 | 69 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | X04388.gene.p01 | Protein | 0.0 | 98 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | M85225.gene.p01 | Protein | 0.0 | 97 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | NC_009782.5559075.p0 | Protein | 0.0 | 95 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | NC_002758.1120355.p0 | Protein | 0.0 | 95 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | AM180355.1.gene636.p | Protein | 0.0 | 93 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | L09756.gene.p01 | Protein | 0.0 | 79 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | AJ295238.gene.p01 | Protein | 0.0 | 72 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | DQ294299.gene.p01 | Protein | 0.0 | 69 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | AY485126.gene.p01 | Protein | 0.0 | 69 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | AJ222769.gene.p01 | Protein | 0.0 | 69 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | FN594949.1.gene24.p0 | Protein | 0.0 | 67 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | L42544.gene.p01 | Protein | 2e-127 | 45 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | AJ514254.gene.p01 | Protein | 4e-122 | 43 |
| HMPREF0837_12207 | YP_003725649.1 | tetracycline resistance protein TetM | Z21523.gene.p01 | Protein | 4e-110 | 41 |
