Gene Information

Name : secA (HMPREF0837_11944)
Accession : YP_003725386.1
Strain : Streptococcus pneumoniae TCH8431/19A
Genome accession: NC_014251
Putative virulence/resistance : Unknown
Product : Sec family type I general secretory pathway preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1787322 - 1789835 bp
Length : 2514 bp
Strand : -
Note : COG: COG0653; Pfam: PF07517,PF01043,PF00271,PF07516,PF02810; InterPro: IPR000185

DNA sequence :
ATGGCTAATATTTTAAAAACAATTATCGAAAATGATAAAGGAGAAATCCGTCGTCTGGAAAAGATGGCTGACAAGGTTTT
CAAATACGAAGACCAAATGGCTGCTTTGACTGACGACCAACTAAAAGCAAAAACAGTTGAATTTAAGGAACGTTATCAAA
ATGGAGAATCACTGGATTCATTGCTTTACGAAGCATTTGCGGTTGTCCGTGAAGGTGCCAAACGTGTCCTAGGTCTCTTC
CCTTATAAGGTTCAGGTCATGGGGGGGATTGTTCTTCACCATGGTGACGTGCCAGAGATGCGTACAGGGGAAGGGAAAAC
CTTGACTGCGACCATGCCGGTATACCTCAATGCCCTTTCAGGTAAAGGGGTTCACGTAGTTACGGTTAATGAATACCTGT
CAGAACGTGACGCGACTGAGATGGGTGAATTGTACTCTTGGCTTGGTTTGTCAGTAGGGATTAACTTGGCTACCAAATCT
CCAATGGAGAAAAAAGAAGCCTATGAGTGTGATATTACTTACTCAACTAACTCAGAAATCGGATTTGACTACCTTCGTGA
CAATATGGTCGTTCGCGCTGAAAACATGGTACAACGTCCGCTTAACTATGCCTTGGTCGATGAGGTTGACTCTATCTTGA
TTGACGAGGCTCGTACACCTTTGATTGTATCAGGTGCCAATGCGGTTGAAACCAGTCAGTTGTATCACATGGCAGACCAC
TATGTAAAATCTTTGAACAAAGATGACTACATCATCGATGTGCAGTCTAAGACTATTGGTTTGTCTGATTCAGGGATTGA
CAGGGCTGAAAGCTACTTCAAACTTGAAAACCTCTATGACATCGAAAACGTGGCTTTGACCCACTTTATCGATAACGCCC
TTCGTGCCAACTACATCATGCTTCTCGATATTGACTATGTGGTGAGCGAAGAGCAAGAAATCTTGATTGTCGACCAATTT
ACAGGTCGTACCATGGAAGGTCGTCGTTATTCTGATGGATTGCACCAAGCTATTGAAGCCAAAGAAGGTGTGCCAATCCA
GGATGAAACCAAGACATCTGCCTCAATCACGTACCAAAACCTTTTCCGTATGTACAAAAAATTGTCTGGTATGACGGGTA
CAGGTAAGACTGAGGAAGAAGAATTTCGTGAAATCTACAACATTCGTGTTATTCCAATCCCAACAAACCGTCCTGTTCAA
CGTATTGACCACTCAGACCTTCTTTATGCAAGTATCGAATCTAAGTTTAAAGCGGTTGTCGAAGACGTTAAGGCTCGTTA
CCAAAAGGGTCAACCTGTCTTGGTTGGTACAGTAGCGGTTGAAACTAGTGACTACATTTCTAAGAAATTGGTCGCAGCTG
GTGTTCCTCACGAAGTCTTGAATGCCAAAAACCACTATAGAGAAGCCCAAATCATCATGAATGCTGGTCAACGTGGTGCC
GTTACCATCGCAACCAACATGGCGGGTCGTGGTACCGACATCAAGCTTGGTGAAGGTGTTCGTGAACTTGGAGGACTTTG
TGTTATTGGTACAGAACGTCATGAAAGTCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG
GTGAGTCACAATTCTACCTATCTCTTGAAGATGATTTGATGAAACGTTTTGGTTCTGAACGCTTGAAGGGAATCTTTGAA
CGCTTGAACATGTCTGAAGAGGCGATTGAGTCTCGCATGTTGACGCGTCAGGTTGAAGCAGCTCAGAAACGTGTCGAAGG
AAATAACTACGATACCCGTAAACAAGTCCTTCAATACGATGATGTCATGCGTGAACAACGTGAGATTATCTATGCTCAAC
GTTACGATGTCATCACTGCAGATCGTGACTTGGCACCTGAAATTCAGTCTATGATTAAGCGCACGATTGAACGTGTCGTT
GATGGTCATGCGCGTGCCAAACAAGATGAAAAACTAGAGGCAATTTTGAACTTTGCTAAGTACAACTTGCTTCCTGAAGA
TTCTATTACGATGGAAGACTTGTCAGGCTTGTCTGATAAGGCCATCAAGGAAGAGCTTTTCCAACGTGCCTTGAAGGTTT
ACGATAGTCAGGTTTCAAAACTACGCGATGAAGAAGCAGTTAAAGAATTCCAAAAAGTTTTGATTCTACGAGTGGTGGAT
AACAAGTGGACAGATCATATCGATGCCCTTGATCAATTGCGTAACGCGGTTGGACTTCGTGGCTATGCTCAGAACAACCC
TGTTGTTGAGTATCAGGCAGAAGGTTTCCGTATGTTTAATGATATGATTGGTTCGATTGAGTTTGATGTGACACGCTTGA
TGATGAAAGCACAAATTCATGAACAAGAAAGACCACAGGCAGAACGTCATATCAGTACAACAGCGACTCGCAATATCGCT
GCTCACCAAGCAAGTATGCCAGAAGATTTGGATTTGAGCCAGATTGGACGCAATGAACTTTGCCCATGTGGTTCTGGTAA
GAAATTTAAAAACTGTCACGGTAAAAGAAAATAA

Protein sequence :
MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLF
PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH
YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQF
TGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ
RIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFE
RLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVV
DGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVD
NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIA
AHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-140 42