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Name : pyk (HMPREF0837_11593) Accession : YP_003725035.1 Strain : Streptococcus pneumoniae TCH8431/19A Genome accession: NC_014251 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 1460981 - 1462486 bp Length : 1506 bp Strand : - Note : COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697 DNA sequence : ATGAACAAACGTGTAAAGATCGTTGCAACTTTGGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTCGGTGAGGATGG ATACTGGGGTGAAAAACTTGATGTTGAAGCTTCAGCTAAAAACATTGCTAAATTGATTGAAGCTGGTGCTAACACATTCC GATTCAACTTCTCACACGGCGACCACCAAGAACAAGGTGAGCGTATGGCAACTGTTAAACTTGCGGAAAAAATTGCAGGT AAAAAAGTTGGTTTCCTTCTTGATACAAAAGGACCTGAAATCCGTACAGAATTGTTCGAAGGTGAAGCTAAAGAATATTC ATACAAAACTGGTGAAAAAATTCGTGTTGCAACTAAACAAGGAATCAAATCAACTCGTGAAGTGATTGCGTTGAACGTTG CTGGTGCTCTTGATATCTATGATGATGTTGAAGTTGGTCGTCAAGTTTTGGTTGACGATGGTAAACTTGGTCTTCGTGTG GTTGCTAAAGATGATGCAACTCGTGAATTTGAAGTTGAAGTTGAAAACGATGGTATCATCGCTAAACAAAAAGGTGTGAA CATCCCTAACACTAAAATTCCTTTCCCAGCTCTTGCTGAACGCGATAACGACGATATCCGTTTCGGTCTTGAACAAGGTA TCAACTTCATCGCAATTTCATTCGTACGTACTGCAAAAGATGTGAACGAAGTTCGTGCAATCTGTGAAGAAACTGGAAAC GGACATGTTCAATTGTTCGCTAAAATCGAAAACCAACAAGGTATCGATAACTTAGACGAAATCATCGAAGCAGCTGATGG TATTATGATTGCTCGTGGTGATATGGGTATCGAAGTACCGTTCGAAATGGTTCCAGTTTATCAAAAAATGATTATCAAGA AAGTCAATGCTGCAGGTAAAGTTGTTATCACTGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT TCAGAAGTATCAGACGTATTCAACGCTGTTATCGACGGAACTGACGCTACAATGCTGTCAGGCGAGTCTGCAAACGGTAA ATACCCACTCGAGTCAGTAACTACAATGGCTACAATCGACAAGAACGCTCAAGCTCTTCTTAATGAATACGGACGTCTTG ATTCAGATTCATTTGAGCGTAACTCTAAGACAGAAGTAATGGCTTCTGCTGTTAAAGATGCTACTAACTCAATGGATATC AAATTGGTTGTAACTCTTACTAAGACAGGTCATACTGCACGTTTGATTTCTAAATACCGTCCAAATGCTGACATCTTAGC ATTGACATTTGACGAATTGACAGAACGTGGCTTGATGTTGAACTGGGGTGTTATCCCAATGTTGACAGATGCTCCATCTT CAACTGACGATATGTTCGAAATCGCTGAACGTAAAGCGATAGAAGCAGGTCTCGTTGAGTCAGGCGATGATATCGTTATC GTTGCTGGTGTGCCAGTAGGAGAAGCTGTTCGCACAAACACAATGCGTATCCGCACAGTACGTTAA Protein sequence : MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAKLIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAG KKVGFLLDTKGPEIRTELFEGEAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN GHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATR SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVKDATNSMDI KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAERKAIEAGLVESGDDIVI VAGVPVGEAVRTNTMRIRTVR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-80 | 45 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 7e-81 | 45 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 7e-81 | 45 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 5e-81 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk | YP_003725035.1 | pyruvate kinase | VFG0479 | Protein | 3e-81 | 45 |
