Gene Information

Name : nrdA (HMPREF0837_11318)
Accession : YP_003724760.1
Strain : Streptococcus pneumoniae TCH8431/19A
Genome accession: NC_014251
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1209179 - 1211338 bp
Length : 2160 bp
Strand : -
Note : COG: COG0209; Pfam: PF08343,PF00317,PF02867; InterPro: IPR013346

DNA sequence :
ATGGGATTAAAACATCTTGAAGACGTGACTTACTTCCGTCTTAATAACGAAATTAACCGTCCTGTTAATGGACAAATCAT
GCTTCATAAAGACAAGGAAGCCTTGGATGCTTTCTTTAAAGAAAATGTAGTTCCAAACACTATGGTTTTTGATTCAATCA
AAGACAAAATCAATTACCTCATTGAACACAACTACATCGAAACAGCCTTTATCAAGAAATACCGTCCAGAGTTCTTGGAA
GAATTGGCTCAATTTATCAAAGACCAAAACTTCCAATTCAAGTCATTCATGGCAGCTTATAAATTTTACAATCAATATGC
CTTAAAGACTAATGACGGTGAATACTATCTTGAAAATATGGAAGACCGTGTCTTCTTCAACGCCCTTTATTTCGCTGATG
GGAATGAAGCTGTTGCAATCGATATTGCCAATGAAATCATCCACCAACGCTACCAACCTGCTACTCCTTCCTTCTTGAAT
GCTGGACGTGCTCGTCGTGGGGAGTTGGTATCTTGTTTCCTAATCCAAGTGACGGATGATATGAACTCTATCGGACGTTC
TATCAACTCAGCTCTTCAACTTTCACGTATTGGTGGTGGTGTGGGAATTACCCTCAGCAACCTTCGTGAAGCTGGTGCAC
CTATCAAAGGCTATGAAGGAGCTGCTTCAGGTGTCGTTCCTGTTATGAAGCTTTTTGAAGACAGCTTCTCTTACTCCAAC
CAATTGGGGCAACGTCAAGGTGCCGGTGTTGTCTACCTCAACGTCTTTCACCCAGATATCATCGCTTTCCTTTCAACTAA
GAAAGAAAACGCTGATGAAAAAGTACGTGTCAAGACTCTATCACTTGGTGTTGTAGTACCTGATAAATTCTACGAATTGG
CTCGTAAAAATGAAGAAATGTACCTCTTCAGCCCTTACTCTGTAGAAAAAGAATACGGTGTGCCATTCAATTACATCGAC
ATTACTGAAAAATACGATGAATTGGTCGCAAATCCAAATATTCGCAAGACAAAAATCAAGGCGCGGGATTTGGAAACTGA
AATCTCTAAATTGCAACAAGAGTCTGGCTATCCTTATGTAGTCAACATCGATACAGCTAACCGTGCAAATCCTGTTGATG
GAAAGATTATCATGAGTAACTTGTGTTCTGAGATTCTTCAAGTTCAAGAACCAAGCTTGATCAACGATGCTCAAGAATTC
CTTCAAATGGGAACAGATGTTTCATGTAATCTGGGTTCAACCAACGTGGTTAACATGATGACTTCACCTGATTTTGGTCG
TTCTATCCGTGCTATGGTTCGTGCCCTTACTTTCGTTACAGATAGTTCACATATCGTAGCTGTACCAACGATTGACCATG
GAAATAGCCAAGCCCACACCTTTGGTCTCGGTGCCATGGGACTGCACAGCTACCTTGCCCAACAACTCATTGAATATGGT
TCACCTGAGTCTGTTGAATTTACAAGCATCTACTTTATGCTTATGAACTACTGGACCTTGGTAGAGTCAAACAATATTGC
GCGTGAACGTGGTATTACCTTCCACAACTTTGAAAAATCAGACTATGCTAACGGAAGTTACTTTGACAAGTATGTAACTG
GTGAATTTGTTCCAACATCAGACCGTGTTAAAGAACTCTTCAAAAATGTTTTTATCCCTGGTGTTGCTGATTGGGCTGAA
CTTCGCGACAAGGTTCAAGAAGATGGTCTTTACCACCAAAATCGCCTTGCTGTAGCGCCAAATGGTTCTATCAGCTATAT
CAACGACGTTTCTGCTTCTATCCACCCGATTACGCAACGTATCGAAGAACGCCAAGAGAAGAAAATTGGTAAAATCTACT
ACCCTGCTGCTGGCTTGTCTACAGAAACCATTCCTTACTACACTTCTGCCTACGATATGGATATGCGTAAAGTCATCGAT
GTTTACGCTGCTGCGACTGAACACGTGGATCAAGGACTTTCACTCACCCTCTTCATGCGCAGTGACATTCCAAAAGGCCT
TTACGAATGGAAGAGGGAAAATAAACAAACGACACGTGACTTGTCCATCCTTCGTAACTATGCCTTTAACAAGGGAATCA
AGTCTATCTACTACGTCCGTACCTTTACAGATGACGGTGGAGAAGTCGGCGCCAACCAATGTGAAAGCTGTGTGATTTAG

Protein sequence :
MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLE
ELAQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYID
ITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEF
LQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAE
LRDKVQEDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVID
VYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 3e-178 52