Gene Information

Name : guaA (HMPREF0573_10214)
Accession : YP_003718027.1
Strain : Mobiluncus curtisii ATCC 43063
Genome accession: NC_014246
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 260260 - 261846 bp
Length : 1587 bp
Strand : -
Note : COG: COG0519; Pfam: PF00117,PF03054,PF00958; InterPro: IPR001674

DNA sequence :
ATGGCTGAAAACTTGCAACACGGTAAACCCGTAGGACCTGTCTTAGTTGTCGACTTTGGTGCGCAATATGCCCAACTTAT
TGCGCGCCGAGTTCGCGAGGCGAAAGTTTACTCGGAAATTGTGGGACATAACCTGACCGCCCGGGAAATATTGGATAAAC
AGCCTTCAGCCATCATTCTCTCAGGTGGACCGTCCTCTGTTTATGCTCCGGGGGCTCCGACCTTTGACCCGGCAGTTTTT
CAGGCAAATGTGCCGGTACTGGGCATTTGCTACGGGTTTCAGGTCATGGCACAAGCCCTGGGGGGCACTGTTAGCCCTAC
CGGAACTTCCGAGTACGGTCGAACCAACTTGGAAGTGACCCCGGACAGCCGGCTGCTGGAAGGAACCCCTTCTGAACAGG
TGGTTTGGATGAGTCATGGGGATGCAGTTTCGGCTGCTCCCAGCGATTTTCAAGTTACCGCGGCGACGGATGATACAAAG
GTAGCAGCCTTTGAGAATCCTGAACGAGGGCTGTATGGAGTGCAGTGGCATCCCGAAGTTCGTCACAGTGCCTACGGTCA
ACGGCTCCTGGAGCATTTTTTGCATGACCTAGTCGGGCTGGATCCGGTGTGGACGCCACAATCCATCATCGACACTCAGG
TGGAGGAGATTCGCCAGCGCGTGGGCGATGCCCAGGTTATCTGCGGATTGTCTGGCGGGGTGGATTCTTCCGTGGCGGCT
GCCCTGGTTCATAAGGCTATCGGTGACCAGCTGACATGTATCTTCGTAGACCACGGTTTGCTGCGTGCGGGGGAGCGCGA
GCAAGTGGAACGAGACTACGCCGCCAACATGGGAATCCGGGTCAAGTCTGTAGACGAGTCCGCCCGCTTCTTGGGAGCGC
TGGCGGGGGTGAGCGAACCGGAACAGAAACGCAAGATTATCGGTCGCGAGTTTATCCGCTCTTTTGAAGCCGCCCAACGT
GAGCTCGTGGCAGAGATTGGCGCCAGCGGTGGGGAAGTGAAGTTCCTGGTACAGGGGACTTTGTACCCCGATGTGGTGGA
ATCTGGTGGCGGCAGCGGCACGGCTAATATCAAGTCGCATCACAATGTGGGCGGATTGCCTGAGGACTTGAAGTTTGAGT
TGATTGAGCCGCTGCGCAAACTGTTTAAAGACGAGGTCCGTGCTCTGGGGCGCGAATTGGGGTTGCCCGATGTCATCGTG
AACCGTCAGCCTTTCCCTGGCCCGGGCTTGGCTATCCGCATCATTGGGGAAGTTACCGAAGAACGCTTGCGGATATTGCG
AGCGGCGGATTTGATTGTGCGCAACGAGCTGAGCGCAGCCGGGCTGGACACGGAGATTTGGCAGTGTCCCGTGGTGTTGC
TGGCAGATGTGCGTTCTGTAGGGGTACAGGGTGATGGGCGGACCTATGGGCACCCCATTGTGTTGCGCCCAGTTTCCTCC
GAGGACGCCATGACTGCGGACTGGTCGCGCTTGGATTGGGAATTGGTGGCGCGGATTTCTAACTTGATTACCAACCAGGT
CCCCGAGGTCAACCGCGTGGTACTGGACTGCACGTCCAAGCCGCCGGGGACCATTGAGTGGGAGTGA

Protein sequence :
MAENLQHGKPVGPVLVVDFGAQYAQLIARRVREAKVYSEIVGHNLTAREILDKQPSAIILSGGPSSVYAPGAPTFDPAVF
QANVPVLGICYGFQVMAQALGGTVSPTGTSEYGRTNLEVTPDSRLLEGTPSEQVVWMSHGDAVSAAPSDFQVTAATDDTK
VAAFENPERGLYGVQWHPEVRHSAYGQRLLEHFLHDLVGLDPVWTPQSIIDTQVEEIRQRVGDAQVICGLSGGVDSSVAA
ALVHKAIGDQLTCIFVDHGLLRAGEREQVERDYAANMGIRVKSVDESARFLGALAGVSEPEQKRKIIGREFIRSFEAAQR
ELVAEIGASGGEVKFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPEDLKFELIEPLRKLFKDEVRALGRELGLPDVIV
NRQPFPGPGLAIRIIGEVTEERLRILRAADLIVRNELSAAGLDTEIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSS
EDAMTADWSRLDWELVARISNLITNQVPEVNRVVLDCTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-169 67
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-134 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-134 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-134 52