Gene Information

Name : HMPREF0573_11154 (HMPREF0573_11154)
Accession : YP_003718967.1
Strain : Mobiluncus curtisii ATCC 43063
Genome accession: NC_014246
Putative virulence/resistance : Virulence
Product : iron (Fe3+) ABC transporter membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 1351715 - 1352608 bp
Length : 894 bp
Strand : -
Note : COG: COG1108; Pfam: PF00950; InterPro: IPR001626

DNA sequence :
GTGAATTTTTATGAAGCTTTCATCGAAATGTGGACGCAACAGTTTATGCTCCGCGGCATCATCGTCACCGGAGTCGCGGC
GGCAGTTTGTGCCGTGTTGTCCTGCTGGCTGGTCTTAATTGGCTGGTCACTGTTAGGTGACGCCCTGTCCCACGCAATTC
TTCCCGGAATCGTCGTGTCCTACCTTTTGGGAACACCCTTCGCAATAGGCGCCCTCGTGGCAGCTTTGCTGGTGGTGGGA
TTGATTGGCGCAGTGCGGGGGCGCGGACGAGTCAAAGAAGACACCGCTATTGGGGTGGTATTCACGACAATGTTTGCCTC
CGGTCTGGTCTTAATCAGCCTGTTCCCCAGTCACATTGATTTGCACCACATTTTGTTTGGCGACATGCTCGGCATTACCA
GAGCCGATATGTGGCAGGTCTTGATATTGAGCCCACTCGCTCTGGTGCTGTTGTTATACAAAAAACGGGATTTGGTGCTG
TATGCCTTCGACAAGACTCACGCCCACGCTATCGGCATCTCTACAAGCTGGTTGGCGACTCTGTTGCTGGTAGCTCTGTC
TTTGACAGTCGTGGTGGCGATGCAGGCAGTGGGCGCAATCCTCATCGTGGCACTGGTGATTACCCCTGGCGCAACCGCCC
GGCTGCTCACAAACCGGTTCAACGCTATGCTATGGATAGCTCCCTTGCTTTCCGTATCCTGCGTCGTGCTGGGAGCTTAT
ATTTCTTACTGGTTCGATACCGCGTCAGGAGCCACAGTCGTGCTGCTTGAAGGCGTATTGTTCCTGATCGTTTGGCTGGT
GGATTTGCTTCGTCAACAGCGTCTGCAGCGCTATCATGGCGCGCAGTCTGCCGCCCCCGGTCCTGACCCGGAACCTCAAC
AGGTTGCTTCTTGA

Protein sequence :
MNFYEAFIEMWTQQFMLRGIIVTGVAAAVCAVLSCWLVLIGWSLLGDALSHAILPGIVVSYLLGTPFAIGALVAALLVVG
LIGAVRGRGRVKEDTAIGVVFTTMFASGLVLISLFPSHIDLHHILFGDMLGITRADMWQVLILSPLALVLLLYKKRDLVL
YAFDKTHAHAIGISTSWLATLLLVALSLTVVVAMQAVGAILIVALVITPGATARLLTNRFNAMLWIAPLLSVSCVVLGAY
ISYWFDTASGATVVLLEGVLFLIVWLVDLLRQQRLQRYHGAQSAAPGPDPEPQQVAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-28 43
sitC NP_461784.1 permease Virulence SPI-1 Protein 2e-28 43
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 2e-28 43
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 2e-28 43
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 2e-28 43
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 1e-27 42
sitD NP_461785.1 permease Virulence SPI-1 Protein 1e-27 42
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 5e-28 41
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-28 41
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 5e-28 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0573_11154 YP_003718967.1 iron (Fe3+) ABC transporter membrane protein BAC0442 Protein 6e-32 44
HMPREF0573_11154 YP_003718967.1 iron (Fe3+) ABC transporter membrane protein BAC0351 Protein 1e-28 43
HMPREF0573_11154 YP_003718967.1 iron (Fe3+) ABC transporter membrane protein BAC0352 Protein 6e-28 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0573_11154 YP_003718967.1 iron (Fe3+) ABC transporter membrane protein VFG0527 Protein 9e-29 43
HMPREF0573_11154 YP_003718967.1 iron (Fe3+) ABC transporter membrane protein VFG0528 Protein 5e-28 42