Gene Information

Name : XNC1_3450 (XNC1_3450)
Accession : YP_003713608.1
Strain : Xenorhabdus nematophila ATCC 19061
Genome accession: NC_014228
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 3347997 - 3349991 bp
Length : 1995 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10574789, 90036864, 94124564, 99288449; Product type e : enzyme

DNA sequence :
ATGCAGCTTTATCTGTGTGAAAAGCCCTCTCAGGCCCGGGATATCGCCCGGGTGCTGGGCGTGAAGCAGCGCGGACAGGG
TTATCTCTTTGGCGACAGTATTATTGTCACCTGGGCTATCGGGCATTTGCTGGAAATGGCTGCACCCGAACACTATGGCG
AACAATTCGGCCCGCCGTGGCGCATGGAACCCCTGCCGGTGCTGCCTGCACAATGGCAGTGGACGGTGAAGAAAGAGACT
GCCGATCAGTTTGCGGTGATCAGACAGTTACTGAAACAGGCCGACGAAGTGATTATCGCGACCGATGCTGACCGTGAAGG
GGAAGTGATTGCCCGGGAACTGCTGGAGTATTGTCATTTTACCGGTCCCGTCAGACGGCTGTGGCTGTCTGCGCTGGATG
AAACCAGTATCCGGCAGGCACTGGCCGCAATATTACCGGGGGAGAAAACCGCGCCGCTCTGGCAGGCCGGACTGGGGCGG
GCACGGGCGGACTGGCTGACGGGAATAAACCTGACCCGCCTGTATACCCTGAAAGCGCAGGCACAGGGATTTGGTGAGGT
GCTGTCCATCGGACGGGTACAGACGCCGACACTGGCTCTGGTCGTGAACCGTGATAACGATATCGCCCGGTTTGAGCCAA
AGCCCTACTGGCAGGTGATGGCCACATTGCAAAAAGATGACATTAGCTTTCGGGCTAAATGGCTGCCTGCGCCCGACGAT
GGCGATGAAGAAAAACGTTGTATCCGGGAGGATATCGCGCAGAGTGTGGTTCAGCGTTGTCAGCAGACACAAGATGCCGT
GGTGACTGAACTCACGCAGAAACGGGAAAAAACCCCGCCGCCGCTCTGTTTTGATTTGGGGATGCTCCAGCAGGTAGCCT
CCCGTCAGTGGGGAATGGGGGCCGGTCAGGTACTGACGATTGCCCAGTCGTTGTATGAAACCCATAAAGCGACCACCTAC
CCGCGCACGGATTGCGGTTATCTGCCGGTTTCGATGCGGGAGAACATTCCGGCCGTGTTCACCGCGCTGACCCGCACCGA
CCCCGCGATGAGTGCCATTATCAGCCAGCTGGATGCCAGCGCTTTTTCCCGTGTCTGGAATGACAGCCAGATCACGGCAC
ACCCTGCCATTATTCCGACCCGCCACACTTTTGATATGACGAAACTGACCGCGGATGAATTAAAGGTCTATCAGTTGATC
CGCCACTATTATCTGGCGCAGTTTCTGCCTGCTCAGGAAACGGATGTGACTGATGTGACATTCACTATCGGCGGGCAGGT
ATTTCAGGCGAAAGGGCGGGTCAGTGTGGTCACGGGCTGGAAGGCACTGTTTGCCGATGAAAAACAGGCGCAGGAGCAGG
AAGACAATACCGCGCTGCCTGCACTGAAAAAAGAGGAAATCAGCCCGGTACTCCGTGCAGAAATACAGCCCCGGCAAACC
CGGCCGCCTGCGCCTTTTACCGAAGGTACGCTGATTGCCGCCATGAAAAATGCGGCGGCGTTTATCCATGATCCACAGCT
TAAAAAAGTGCTGCGGGAAAGTGCCGGTCTGGGCACGGAGGCCACCCGGGCCGGTATCATTGAAGCCCTGTTTAAACGCC
GGTTACTGGCGCGAAAAAAGAAAAACCTGCATGCAACGCAGCTGGCGCAGGAGCTGATAGCCGGGCTGCCGGATGTCCTG
ACCCATCCGGGCATGACGGCACTCTGGGAACAGTCACTGGACGACATTGCCCGGGGCCGGACCACACTGGATGGCTTTAT
GCAGAAACAGGCACAGTGGCTGGCGCATTTAGTGGAAAAGGGCAAAACACAGCCGATCCGGTTTACCCTGCCGAAAACCC
CGGCGTGCCCGCGCTGTGGCGGCCCGATGCAAAAACGGGCGGGAAAAACAACCCCGTTCTGGGGCTGCACCCGCTATCCG
GCATGCAAAGGGATGCTGAACGCTAACGCGGTGATCGGCTCCCGAAAAACCCGGCGGGGAAATTCGCCGGACTGA

Protein sequence :
MQLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPAQWQWTVKKET
ADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCHFTGPVRRLWLSALDETSIRQALAAILPGEKTAPLWQAGLGR
ARADWLTGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMATLQKDDISFRAKWLPAPDD
GDEEKRCIREDIAQSVVQRCQQTQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYETHKATTY
PRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDASAFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLI
RHYYLAQFLPAQETDVTDVTFTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTALPALKKEEISPVLRAEIQPRQT
RPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEALFKRRLLARKKKNLHATQLAQELIAGLPDVL
THPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYP
ACKGMLNANAVIGSRKTRRGNSPD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 58
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 57
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 57
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 57
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-154 48
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 6e-141 48
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 5e-149 47
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 2e-156 46
topB AAW83109.1 TopB Not tested GGI Protein 4e-122 41