Gene Information

Name : XNC1_2387 (XNC1_2387)
Accession : YP_003712613.1
Strain : Xenorhabdus nematophila ATCC 19061
Genome accession: NC_014228
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III, type 1
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2317629 - 2319815 bp
Length : 2187 bp
Strand : +
Note : -

DNA sequence :
ATGGACCTTTATATCTGCGAAAAGCCTTCTCAGGCCAAAGACTTGGCAGGAGTAATGAAAGCCTCCCAAAGGGGAGATGG
ATTTATCCATGATGGAGGAAACAGAGTTATTACCTGGGCCTTCGGCCACCTTCTGGAATTGTATATGCCAGATGACTATG
ACGAACGATATAAGTCATGGTCACTAGAGACTCTTCCCATTGCTCCTGACGCCTGGCGGTACAACGTTCGCAAGAGTGCG
CTAAAGCAGTACAAAATCGTTGAAGGCCTAGTCAAAAAAGCAAGTACCATCTACATCTCTACCGACTTCGACCGCGAAGG
TGAAGCTATCGCTCGTTCGCTTTTGGATCAATTCCGCTACTCAGGTCCTATTCGTCGTGTTTGCTTGACTGCACTCGATG
AGTCGAGCATTAAGAAAGCGCTAAATAACGTTAAGGACGGCAAAGAAACTGTCTCGCTATACTACGCTGCACTAGCAAGG
CAACGCGCAGACTGGCTGGTGGGAATGAACGTAAGCCGACTCTATACAGTATTGGCGCGAGATGTAGGTTTCAATCATAC
CCTCCACGTAGGTCGGGTCATTACACCTACCGTCGCTCTCGTGTGTCAACGAGATCGAGAGATCGCGGGTTTCACACCAT
CCCCATACTGGACTCTGGGCGTGAACGTATCCGTGCAGAATGGTCAGTTTGCCGCTCAGTGGATACCGCCAGAGGAGTGT
AGTGACGAACAAGGCCGATGTATCAATAAGGCCTATGCCGAGCAGGTATCCTCTCAGGTCAACGGTGCCAATGCAGTTAT
CAGCAAGGCAGAGACAAAACCAGGCAAAGAGTCTGCCCCCCTCCCCTTCGATCTGACGTCGTTACAACAATACGCAAGCA
AACGATGGGGATATACTGCTCAGCAGGTACTGGATGCAGCCCAAGCTCTGTACGAGACGCACAAAGCAACAACCTACCCT
CGTACCGACAGTCGTTATCTACCCGAGAGCCAAAAGGAGAACATCCCGGACATTCTCCAGGCGCTTATTTTGTCCGATCA
GAACGTTTCAGGGCTGGTAGCTGGCGCAGATCCTCACCGCAAAGCCAGAGTATTCAATGACTCTAAAGTGACCGCGCACC
ACGCGATCATTCCAACCCCAGCAAGAACAGACATCAGTGCCATGTCTGAGATCGAGTTAAATCTCTACGACGCCATACGT
CGTTTCTACATCGCGCAGTTCTACAGTGAGTTCGAGTTCACCAAAACCTCCATCGAGGTGCAGTGTGGACGTCACCTCTT
TGCAGCTTCCGGTAAGACTCCGACCAAACAAGGCTGGAAGGTTTTGTTTGCTTCTGACAGCGAAAGCAGCCCCAAGGATG
AAGGAGAAGATACCGACGCGCCGGTTGAACAGGAGAAGCTCCCCAGGGTTAGTCAGGGCGAACCTGCCTTGCTCAATGGT
ACTGAGCTGATGAACAAAATGACGCGGCCAGCACCACACTTTACAGAAGCCACATTACTTGCCGCGATGGAGAACATTGC
CCGGTTTGTGACTGAGGAGAAGTTTAAGCAGATCCTCAAAGACACCGCCGGTCTGGGCACTCCAGCAACACGCGCCAGCA
TCATCCAGGGAACTGTAGATAAAGGCTATTTCAAGCGTCAGAAAAAGGTACTGCTTGCAACAGATAAAGCTCATGCACTT
ATCGCTGTGCTTCCACCAGCAATCAAGTCACCTGGCATGACTGCGGCCTGGGAACAAGAGCTTGAAAAAGTCGCCACTGG
CTCCGGCAACATGTCTGTCTTCATGAAACAGATTTCCACCTGGATTTGCCAGATGGTCGATCAGCTCAAAGTGGCCGCAC
CGGTTCTGACCAAAGAAGGCAGTGCGATGGCTAAGGCATTTGAAGGCGCGAAACCTCCCTCACACGAATGCTTCAACTGT
GGTGGAGAGATGCACCGAATCAAAGGGAAAAACGGCTTCTTCTGGGGTTGTCAGAACGAGGCTTGCAAAAAGACATTCCC
AGACAACAGGGGCAAACCTGAGAAGCGTATCGCTGCGGAGGATTGCCCAGACTGCCCAGATTGCGGTAGCCCGATGCGCC
TTAGAAAAGGGAAAGCACCAGGTAAAAAACGAGCCTCTAAGTTTTGGGGTTGCACCGCTTATCCAGACTGCAAAGGCACA
ATGCCTTTCAAAAAATCAGACTTATAG

Protein sequence :
MDLYICEKPSQAKDLAGVMKASQRGDGFIHDGGNRVITWAFGHLLELYMPDDYDERYKSWSLETLPIAPDAWRYNVRKSA
LKQYKIVEGLVKKASTIYISTDFDREGEAIARSLLDQFRYSGPIRRVCLTALDESSIKKALNNVKDGKETVSLYYAALAR
QRADWLVGMNVSRLYTVLARDVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC
SDEQGRCINKAYAEQVSSQVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGYTAQQVLDAAQALYETHKATTYP
RTDSRYLPESQKENIPDILQALILSDQNVSGLVAGADPHRKARVFNDSKVTAHHAIIPTPARTDISAMSEIELNLYDAIR
RFYIAQFYSEFEFTKTSIEVQCGRHLFAASGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALLNG
TELMNKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGTVDKGYFKRQKKVLLATDKAHAL
IAVLPPAIKSPGMTAAWEQELEKVATGSGNMSVFMKQISTWICQMVDQLKVAAPVLTKEGSAMAKAFEGAKPPSHECFNC
GGEMHRIKGKNGFFWGCQNEACKKTFPDNRGKPEKRIAAEDCPDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGT
MPFKKSDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-141 43
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-132 43
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 8e-131 43
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 4e-136 43
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 2e-140 42
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 8e-131 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 8e-131 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 6e-131 41