Gene Information

Name : clpB (wcw_0840)
Accession : YP_003709212.1
Strain : Waddlia chondrophila WSU 86-1044
Genome accession: NC_014225
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 907704 - 910313 bp
Length : 2610 bp
Strand : -
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGCTCAGAATTTCACAGATGCAGTCTCAACAGCGATACAAGAAGCGTTTGCAAACGCGCAGTCGCGAAAAAATCCGGA
AGTCACGGAAAACCACCTTCTTCTAGCCTTTCTCGAAGATCCGAAAGGGTATTTTCAATCGGTACTTAACAACCTAAATA
CTCACCCTTATCAATTGCAATCCCAAGTGAAAGACCTCTTGCAGCAGCTTCCCACTTTCGAAGGAAGCGGCACAGAACCT
CCTCAAGTCGCACGCAATCTTCAAGGAAGAATCACTGATGCCGAACAGATCGCAAAGCAATGGCAAGATTCATACATAAG
CAGCGACCATTTCCTTCTATCGTTTTGGAAAAATGGAGGCGAACCATTTATCTCTTGGAAAGGGCAGGCAGGAATCTCTT
TTAGGCAACTCGAAGAACATATCAAAAAAATGCGTGGAAACCGTCATATAGACTCCCCTGCCGCTGAACAAAGCTTGCAA
GCTCTCGACAAATACTGCCGCAATCTGACTAAGCTGGCGCGGGATGGCAAAATGGATCCTGTGATCGGCAGAGATGAAGA
GATCAGACGGACAATGCAAGTCCTTAGCCGACGAACCAAGAACAATCCCATGTTGATTGGAGAGCCCGGCGTCGGAAAAA
CGGCGATTGCAGAGGGAATGGCTCTTCGGATCATCCAAGGAGATGTCCCCGATTCTCTTAAAGACAAGCAAATATATGCC
CTCGACATGGGATCTCTGGTTGCCGGCACAAAATACCGCGGCGAATTTGAAGAGCGGCTAAAAGGAATCCTTGAGGAAGT
CGAATCGAATGAAGGCAAAGTGATCTTGTTTATCGATGAAGCGCATACGCTGATCGGTGCCGGAGCGGTCGAAGGGTCAA
TGGACGCTGCCAATCTGCTTAAACCTGCCCTAGCTAGAGGAACGCTTCATTGCATCGGCGCCACAACATTGGGAGAGTAT
CAAAAACACATAGAGAAAGACCCTGCGCTGGAAAGACGTTTCCAGCCGGTAACGATTCGCGAACCATCTCTTGAAGATTC
GATTGCTATTTTGAGAGGGTTAAAAGAGCGTTACGAAATTTTCCACGGTGTAAGGATTACCGAATCCGCTCTTCATGCAG
CTGTCTTTCTTTCCTACCGCTATATCACAGACCGAAGACTACCCGACAAAGCGATCGACCTTATTGACGAAGCGGCCAGC
ATGATTAGAATGCAAATTGGAAGCCGTCCCCTTCCCATCGACAACAAAGAGAGAGAGCTTTCCAAATTAATCGTTGAACA
AGAAGAAGTGCGCAGAGAAAATCCTGAAAGCGAAAATATTGCCAAACTCGAAGAGAAAATCGCTTCGATTAAGGAGGAGC
TAAGCGCTTTAAAAGAGCAGTGGGAAGAAGAGAAAAAATTAATTAACAACCTTAAACAAAAGAAAAACGAACTCGAGCAG
CTCCGTTTTCAAGAGGAGGAGCTTGAACGAAAGGCTGACTACCAAAAAGTAGCCGAGCTGCGCTATGAAAAAATTCCCGC
TCTGAAAAAAGCAATTGAAGAAGCCCAGGAAAAACTTAATGCTAAACCGAACCGTCTGCTTCAAGAAGAGGTTGATGAAC
AATTAATCGCTCAAATCGTCTCTAAATGGACGGGAATCCCTGTCAGTAAAATGATGGAAGGAGAAGCGGAAAAACTTTTG
CATCTTGAAAAAGAGATTGGCAAACGGGTCATCGGTCAGGAAATGGGTGTGAAAGCAGTTTCCGAAGCGATCCGCCGCTC
CCGTTCCGGACTGAGCGATCCCAATCGGCCTATCGGAGCGTTTTTGTTTTTGGGACCGACTGGCGTCGGAAAAACAGAAC
TTGCAAAATCTCTTGCAGAACAGCTATTCGATCAAGAAGAGGCCATGATCCGCCTAGATATGTCTGAATATATGGAAAAA
CACGCCGTATCAAAGCTGATCGGCTCTCCTCCAGGCTATGTCGGATATGATGAGGGAGGACAGCTGACAGAAGCTTTGCG
CCGCCGCCCCTATACCGTCGTTTTACTAGACGAAGTAGAAAAAGCTCATCACGATGTATTCAACATCCTGCTGCAAATTT
TTGATGATGGAAGGCTGACCGATAGCAAAGGAAGAGTTGTTAACTGCAAAAATGCTCTTTTTATCATGACTTCAAATCTC
GGATCGGACTTACTGCTTCAACAGATGGAGAAAGATCCCTCTTCAATCACGAAAGAGAGCATTGTCAAATTATTAGAGCC
CGTGATCCGACAGCATTTCCGTCCAGAATTCATCAACAGGTTAGATGAAATCCTCCCCTTCTTGCCTCTTCAGCAAAAGG
ACATGGAAAAAATTGTCATGATCCAACTCCAACATCTTAAACGACGTATGGCTGACCGGGAGACAAAGCTGACCTGGTCG
GATGATGTGGTCAAATTTTTGGCTAACAAAGGCTATGATCCCTCTTTCGGTGCGAGACCTCTGAAAAGACTGATCCAGCA
TGAAGTGGTAAATAAGCTGTCGACAGCAATCCTAGAAGGGAAAATTCCCTCTAATAGCACCGTTCACCTAATGTTGGATG
GAGACGAAGTTGGATTTATACCGAACAAACTTCAAGAATCGGAATTTTGA

Protein sequence :
MAQNFTDAVSTAIQEAFANAQSRKNPEVTENHLLLAFLEDPKGYFQSVLNNLNTHPYQLQSQVKDLLQQLPTFEGSGTEP
PQVARNLQGRITDAEQIAKQWQDSYISSDHFLLSFWKNGGEPFISWKGQAGISFRQLEEHIKKMRGNRHIDSPAAEQSLQ
ALDKYCRNLTKLARDGKMDPVIGRDEEIRRTMQVLSRRTKNNPMLIGEPGVGKTAIAEGMALRIIQGDVPDSLKDKQIYA
LDMGSLVAGTKYRGEFEERLKGILEEVESNEGKVILFIDEAHTLIGAGAVEGSMDAANLLKPALARGTLHCIGATTLGEY
QKHIEKDPALERRFQPVTIREPSLEDSIAILRGLKERYEIFHGVRITESALHAAVFLSYRYITDRRLPDKAIDLIDEAAS
MIRMQIGSRPLPIDNKERELSKLIVEQEEVRRENPESENIAKLEEKIASIKEELSALKEQWEEEKKLINNLKQKKNELEQ
LRFQEEELERKADYQKVAELRYEKIPALKKAIEEAQEKLNAKPNRLLQEEVDEQLIAQIVSKWTGIPVSKMMEGEAEKLL
HLEKEIGKRVIGQEMGVKAVSEAIRRSRSGLSDPNRPIGAFLFLGPTGVGKTELAKSLAEQLFDQEEAMIRLDMSEYMEK
HAVSKLIGSPPGYVGYDEGGQLTEALRRRPYTVVLLDEVEKAHHDVFNILLQIFDDGRLTDSKGRVVNCKNALFIMTSNL
GSDLLLQQMEKDPSSITKESIVKLLEPVIRQHFRPEFINRLDEILPFLPLQQKDMEKIVMIQLQHLKRRMADRETKLTWS
DDVVKFLANKGYDPSFGARPLKRLIQHEVVNKLSTAILEGKIPSNSTVHLMLDGDEVGFIPNKLQESEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-140 45
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-112 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003709212.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2076 Protein 5e-120 43