Gene Information

Name : cadA (wcw_0743)
Accession : YP_003709116.1
Strain : Waddlia chondrophila WSU 86-1044
Genome accession: NC_014225
Putative virulence/resistance : Resistance
Product : heavy metal transporting ATPase, P- type
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.1.-
Position : 816568 - 818442 bp
Length : 1875 bp
Strand : +
Note : Cation transport ATPase

DNA sequence :
ATGCTGGCCGATCCAAAATTGCGCTGGCTGATCTTTTCTGCTTTTCTTGTTGCGATTTTTGAGATTTTATCCCTCATAGG
AATCCGGCTTGAGCCGAGCGAAGGGGCGTTTGTTTTTGGGGTGATTATCCTGGGAATTGGCTACCAAGTTATCTGGGATG
GCTTAAAAGCTCTATTCACATTGAAATTCAGCAGCATCAACCTTCTAATGTTAGTGGCGGTTATCGGAGCTTTCTATATT
GGAGAGTATGAGGAAGCTGCTGTTGTCATTGTGTTGTTTTCCCTTGCCGAGCGTCTGGAATATGTTGGAATTTCAAAAAG
CAAATCTTCTTTGGACGCTCTTGTCGATGGAATGCCTAAATATGTGAAAATCAGAGGATTGGATGAACCTATTGATGTCT
TACAAGTGAGTGTTGGAGATATTATTGTAGTCAATCCTTATTCATTGATTCCATTGGATGGCGAAGTGGTTGGAGGCGTT
TCCTTTGTCGATGAGTCGACCATGACAGGGGAACCGATTCCTGTTGATAAAAGAGCGGGAGACAAGGTATTTGCCGGTAC
GATGAATAAAAAAGGAGGGCTTGAGATCCGGGTTTCGAAGACAACCGGTTACAGAGCTGTGGATAAAATTCGAGAGATGA
CCTTCAATGCGATCAAACACAAATCTCAGACACAGCAATTTATTGAGCAGTTTTCCTCTTATTATACTCCGGCGATTTTA
TTGCTGGCGTTGATCATCGCTTTCCTCCCACCTCTTTTTGGATTGCGCGGTTTTGAAGAAAGTTTTAAGCAATCGTTGGC
ACTTCTTGTGATCTCGTGCCCTTGCGCTCTTGTGATTTCAACACCTATTGCCATCTATTCTGCGATTGGAAACGCCACTT
CTGCCGGTGTTTTGATTAAGGGAGGGCGCTATTTGGAGGCAATGGGGCAGTTGAAAGCGATTGCGTTTGATAAGACACGT
ACTTTGACTTATGGCAAGCCGGTTGTCACGGATGTGATCCCTTTCAATGGTTGTTCGAGAGAGGATTTATTGAGTTGTGC
AGCAGGAGTCGAATTATTTTCCGAGCACCCGTTAGCGCAAAGCATTGTAGATGCAGCAAAAAAGGAGGGGTTAACTCCTC
ACAAAGTGGAAGAGTTTGAGAGTGTTGTCGGAAAAGGCGCTAAGGCTGAGTGCCTGGTCTGTCCGGATCGTCATCACTGT
GTTGGCAAGCTGGATTTCATTCTTGAAGAGCATCATGTGCCCGAAGAGGTGAGGTCTGAACTGTCGCGGTTGCAAAACGA
GGGGAAAACGGTGATCATTGTTTCTTCGGATAGACAAGTTGAAGGGGTCATCGCTATTGAAGATGAGGTAAGATCCGAAG
CCGCTGGCGTGGTTAAAGCTCTTCTGAATTTTGATATTAAAAGCGTGATGTTGACTGGCGACAATGAGCTTGTTGCCAAA
GCGGTAAGTAAAGTTGTGAAAATCAAACAGTTGAAATCAGAACTTCTTCCGCAAGACAAGGCTAGGGAGGTAGCAGCTCT
TGTAAAAAAGCATCAAATTGTCGGAATGGTTGGTGATGGCGTCAACGACGCGCCGGCTCTTGCTTCTGCAACCGTTGGGA
TTTCCATGACATCCCTTGGCAGTGACAGTGCGATTGAAGCGGCAAATATCGTTATTCTTAACGATCATTTAAAGATGATC
CCATATTTGGTTCGGCTTGGCAGGGAAGCATTAGGTCTTATTCGATTCAATACCACTTTCGCACTTGTTTTGAAATTTTT
ATTTGTCGCTTTAGCCATTTTTGGAATGAGCAATCTTGCTTTAGCCATTTTTGCTGATGTTGGTGTGACGTTGATTGTTA
TTTTAAACAGTCTTCGACTGTTAAGTTTTAAATAG

Protein sequence :
MLADPKLRWLIFSAFLVAIFEILSLIGIRLEPSEGAFVFGVIILGIGYQVIWDGLKALFTLKFSSINLLMLVAVIGAFYI
GEYEEAAVVIVLFSLAERLEYVGISKSKSSLDALVDGMPKYVKIRGLDEPIDVLQVSVGDIIVVNPYSLIPLDGEVVGGV
SFVDESTMTGEPIPVDKRAGDKVFAGTMNKKGGLEIRVSKTTGYRAVDKIREMTFNAIKHKSQTQQFIEQFSSYYTPAIL
LLALIIAFLPPLFGLRGFEESFKQSLALLVISCPCALVISTPIAIYSAIGNATSAGVLIKGGRYLEAMGQLKAIAFDKTR
TLTYGKPVVTDVIPFNGCSREDLLSCAAGVELFSEHPLAQSIVDAAKKEGLTPHKVEEFESVVGKGAKAECLVCPDRHHC
VGKLDFILEEHHVPEEVRSELSRLQNEGKTVIIVSSDRQVEGVIAIEDEVRSEAAGVVKALLNFDIKSVMLTGDNELVAK
AVSKVVKIKQLKSELLPQDKAREVAALVKKHQIVGMVGDGVNDAPALASATVGISMTSLGSDSAIEAANIVILNDHLKMI
PYLVRLGREALGLIRFNTTFALVLKFLFVALAIFGMSNLALAIFADVGVTLIVILNSLRLLSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 8e-84 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-83 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-83 41