Gene Information

Name : guaA (wcw_1658)
Accession : YP_003710009.1
Strain : Waddlia chondrophila WSU 86-1044
Genome accession: NC_014225
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1771944 - 1773542 bp
Length : 1599 bp
Strand : +
Note : GMP synthase, PP-ATPase domain/subunit

DNA sequence :
ATGCAAAATTTAACCCAATCCACTTCGATATTTCATGAAATGTCTGGATCAGACTCCATCCTAATTCTGGATTTCGGATC
GCAATATACGCAGCTAATTGCCAGACGGATCAGAGAACTCGGTGTCTATACCGAAATCCTGCCTCCTGAAACCCCTTTTA
GCGCTTTATTGTCCATGAAGCCTAAAGGGCTAATCCTCTCCGGCAGCCCAAGTTCCACACATGGACAGCCACTGATATGC
GATCCAGAAATTGCAAACTCTCCTATCCCTGTGCTGGGAATTTGCTATGGAATGCAGCTTCTCAATAGGCTGCATAAAGG
AACTGTCATCCCCTCTCGAAACGGAGAATACGGAAAACAACCTATTTCCCTCCATTCCTGCGAAGGGATCTTTAAGGGGT
TGGATTCCCACCAAATGGCTTGGATGAGCCATGGAGACAGCATCAACCGCCTTGCCGATCCGCTCATTGCTACCGCTCAA
AGCGAAAACGGCCACATCGCAGCGATGCAGCACACCTCCCTTCCACAATATGGAGTACAGTTCCACCCCGAAGTGACCCA
CACAGAAAACGGAAAGGAAATCTTGCACAATTTCATTCAGATTTGCCAATGCAAACAAACCTGGTCTTTGAAAAATCATA
TCGAATCGGCAAAAGAGGAGATTAGGAAGCAGGTAGGCAACGGTACAGTGATCAGCCTAGTTAGCGGAGGAGTCGATTCA
ACCGCAGCAACTTTTCTTTGTTTTGAAGCTCTTGGATCTGAAAAGGTGATCCCTTTGCATATCGATACCGGTCTAATGCG
AGCGGGAGAATCAAAAGAAGTGTGCGCATTACTCCGCTCACACGGTATGCGGCATCTTGATTTTGTCGATGCCTCTGATG
AGTTCCTGGACGCTCTTAAAGGAGTGGAGAATCCGGAAAAAAAACGGACGATCATCGGCAACCTCTTCATAGAAATTTTA
GAAAGGGAAATCGCAAAAATTGAGAACAAAGGCACCTGCACATTTTTATGCCAAGGCACCCTTTATACCGATTTAATCGA
AAGCGGACAAGGAGTGGGCAAACATGCGGATGTGATCAAGACCCACCACAATGTCAATCCACCAGTTGTCCAAAGAAAAA
GAGAGCAAGGCTTAATCGTTGAGCCAAACAACAAAATCTTCAAGGATGAGGTGAGAATATTGTGTGAACAGATGGGAGTT
CCTTCCTCACTGGCCTGGCGCCACCCTTTCCCCGGTCCCGGGCTGGCGATCCGCATTTTAGGCGAGGTGACCAAAAGTCA
GCTTGAATGCTTGAGGGCAGCTGATGCCATCTATTTGGAAGAGATTGTCAAAGCGGGTCTTTACGATGAGATCTGGCAAG
CATTTGCCTGCTTGTTACCTGTATCCACTGTCGGCGTGATGGGTGATAAACGCACTATCGGACAAGTGATTGCATTAAGA
GCTGTCAGCAGCATTGATGGAATGACTGCGGATTTTTTCCCTCTTCCAATGGAACTTCTCAGCAAAATCAGTACGCGGAT
CATCAACGAAGTGCCAGAAGTTAATAGAGTGGTCTACGACATAACTTCCAAACCTCCTGGAACCATTGAGTGGGAGTGA

Protein sequence :
MQNLTQSTSIFHEMSGSDSILILDFGSQYTQLIARRIRELGVYTEILPPETPFSALLSMKPKGLILSGSPSSTHGQPLIC
DPEIANSPIPVLGICYGMQLLNRLHKGTVIPSRNGEYGKQPISLHSCEGIFKGLDSHQMAWMSHGDSINRLADPLIATAQ
SENGHIAAMQHTSLPQYGVQFHPEVTHTENGKEILHNFIQICQCKQTWSLKNHIESAKEEIRKQVGNGTVISLVSGGVDS
TAATFLCFEALGSEKVIPLHIDTGLMRAGESKEVCALLRSHGMRHLDFVDASDEFLDALKGVENPEKKRTIIGNLFIEIL
EREIAKIENKGTCTFLCQGTLYTDLIESGQGVGKHADVIKTHHNVNPPVVQRKREQGLIVEPNNKIFKDEVRILCEQMGV
PSSLAWRHPFPGPGLAIRILGEVTKSQLECLRAADAIYLEEIVKAGLYDEIWQAFACLLPVSTVGVMGDKRTIGQVIALR
AVSSIDGMTADFFPLPMELLSKISTRIINEVPEVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-109 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-109 49
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-109 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-88 45