Gene Information

Name : metB (wcw_1145)
Accession : YP_003709508.1
Strain : Waddlia chondrophila WSU 86-1044
Genome accession: NC_014225
Putative virulence/resistance : Unknown
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1224294 - 1225442 bp
Length : 1149 bp
Strand : +
Note : Cystathionine beta-lyases/cystathionine gamma- synthases

DNA sequence :
ATGAAATTTAAAACGCTAGCCATTCACAAAGGGTCTAAGCCAGATGCCGAAACAGGGGCTGTCATGCCGCCTGTCTACTT
GACAAGTACATTTGAACAAAACACTCCAGGACAAACACGAGGCTACGACTACACAAGAGGAGGAAATCCCAATTTTACAC
GGCTGGAAAGCCTCTTAGCCTCATTGGAAAACGGGAAATACGCAACTGTTTTCTCTTCAGGATTAGGGGCGCTGTCGGCA
ATGGCAGCCATGCTAAAGTCCGGAGATCAAGTGGTCGCCTTAAATGGCCTCTATGGAGGAACCTACCGATTCTTCACACA
AATCATGCAGAAGCAAGGAATCGCTTTCGAGGTGATCGACGTTAAGGACATTGATCGCGCCCTCGCTCAAAAACCCGCCT
GGCTTCTATTTGAAACGCCGACAAATCCCTTACTGGACATCTATGATATCAAGCGGCTTTGCGCTCATGCAAATGCATTA
GGAGTTTTAACCATCGTCGACAATACCTTTGCAACGCCCTATTTCCAAAATCCCTTGCAACTAGGCGCAAGCGTTGTTTG
GCATAGTACAACAAAATACATCGGAGGCCATTCAGATGTTGTCGGAGGCGCTCTCATCACCAACAGCCAACAACTCAATG
AACAGTTTTCTTTCAACCGTCTGTCAATCGGAGTCAACCCAAGCCCGTTCGATGCATGGCTGACGATGAGAGGGGTTAAA
ACACTTGCCCTCAGAATGGAACAACATCAAAAGAACGCGCTGGCGCTGGCCGATTTTTTATCCGGGCATCCACTGGTCAA
AAAAATTTATTATCCCGGGATCGAGACCCATCCAAACCATGAAGTTGCAAAACAGCAAATGTCCGGATTCAGCGGAATCG
TATCAGCAGAATTCAACCTTTCTCTTGAACAAACATTAAAACTGATCAGCCGCTTCTCCTTGTTTACACTTGCTGAAAGT
CTAGGAGGAGTCGAATCATTGGTCAATCATCCGGCAACCATGACCCATGCATCAATTCCAAGGGAAAAAAGACTTAAAAT
GGGAATTTCGGATGGACTGATCCGTTTTTCCCTTGGAATCGAAGATGCTGAAGACCTTATTAAAGATGTCAAAACTCAAT
TGGAAAAATTTTCTTTGAATCCATCATGA

Protein sequence :
MKFKTLAIHKGSKPDAETGAVMPPVYLTSTFEQNTPGQTRGYDYTRGGNPNFTRLESLLASLENGKYATVFSSGLGALSA
MAAMLKSGDQVVALNGLYGGTYRFFTQIMQKQGIAFEVIDVKDIDRALAQKPAWLLFETPTNPLLDIYDIKRLCAHANAL
GVLTIVDNTFATPYFQNPLQLGASVVWHSTTKYIGGHSDVVGGALITNSQQLNEQFSFNRLSIGVNPSPFDAWLTMRGVK
TLALRMEQHQKNALALADFLSGHPLVKKIYYPGIETHPNHEVAKQQMSGFSGIVSAEFNLSLEQTLKLISRFSLFTLAES
LGGVESLVNHPATMTHASIPREKRLKMGISDGLIRFSLGIEDAEDLIKDVKTQLEKFSLNPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-69 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-70 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-53 43