Gene Information

Name : Slip_0800 (Slip_0800)
Accession : YP_003702145.1
Strain : Syntrophothermus lipocalidus DSM 12680
Genome accession: NC_014220
Putative virulence/resistance : Resistance
Product : ATPase P
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 833972 - 836350 bp
Length : 2379 bp
Strand : +
Note : COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR018303:IPR017969:IPR001366:IPR 001757:IPR008250:IPR005834:IPR006404:IPR006416; KEGG: swo:Swol_2086 cadmium-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport

DNA sequence :
ATGGACAAAGCTGTAACAATTCCAGATGCTGCGTTTTCGGCCGACATCTATGTCAGGGGAATAGACTGCCCTGATTGTGC
GGCCAGGGTAGAGCAGGCAGTTAAAGGGTTACCCGGGGTAATTAACGCCAAGGTGCTGGTGAGGTCCAGCAAGCTGGCTT
TTCTGTATGACCCGGCTCTGATCGAGGTTGAACAGGTAGTCTCCAAAGTGAGTGAATTGGGATACACAACAACAAAGGCG
GAGGGGTGTTCAAACACCGGTGCTTTAGCCGAGGGTATTACCAGCACTATTCGAATTTTCGGCCTCGATTGCGGGGATTG
TGCTGCCAAGCTGGAAACGGGTCTGAGGCGAATTCCCGGTGTAAAACGAGCTGTTGTTAACCTTGCTCTTTCCAAGGTTG
AGGTTGACCACAGCGGACCGTTGCCGGAAATCCTAAAGACCATTGAAGCTATGGGTTACACGGCAAAGCTAGAAGATAGA
CGCCTTAAGTCAGGGTTTGACGGGCAAAACACTGCCACTAGCAAGTATGCGTTGCCAACGGTTTTATCCGGAACTATGGT
AGCGATAGGATTATTTTTCGGTCTTCTCGGTCTGCCCGATTCGATAGTAAGTGCTGCTTATTTGGTCGCCATCTTGTTTG
GGGGATATTTACCTGCCCGAAACGGTTGGGCGATCATCAGGAGTGCCAGAGAACTTGACATGAACGTATTAGTAGTGATT
GCCGTCGCGGGAGCGGTCGCTATAGGGCGCCTGGAAGAGGCGGCAGCGGTGGTATTCTTGTTCTCGCTCGGTAACACTTT
ACAGGGTTACACTTTCGAAAGGACCAGGAGTTCAATCAGAGCCTTGATGGAACTCGCACCCGACGAGGCAGTCGTTCGGC
GGGACGGGCGTGAGGAGGTACTGTCAGTGCAGGATATCCGGATTGGAGATGTAGTAATAGTGCGCCCGGGTGAGCGTGTG
CCCGTAGATGGCAGGATATTGGAGGGAACTACTTTTGTCAACCAAGCTGCCATAACCGGAGAGTCGGTGCCGGTGGAAAA
GAAACCCGGTGATGAGGTCTTAGCAGGAAGTATTAACGGAATGGGGGCTCTTGAGGTTGAGGTCACCAGAGCTGCCCAGG
ACAACACGGTATCGAGGATCATCCGTTTGGTAGAACAAGCGCAGACCCAGCGGGCTCCTTCACAGCAAACAGTAGATAGG
TTTGCCCGCTACTATACTCCAATCGTCATAACAGCAGCAATCCTGGTTGCAATAGTTCCCCCTTTGGGATTACACCAGCC
TTTTAACAAGTGGCTGTATGAGGCTTTGGCCATGTTGCTGGTCGCTTGTCCTTGTGCCCTTGTCATCTCGACTCCGGTTG
CTGTAGTGGCGGCGTTGGGGAATGCGGCCAGAAACGGGGTCTTGATAAAGGGTGGAGGTTACCTAGAAGAGGCCGGAACT
CTTTCTGTTGTTGCCTTTGACAAGACCGGCACCTTGACGGTGGGAGAACCGAGAGTAACTGATGTGGTTCCGCTAACGGC
CACAGCTCAGGAAGTAATCCAGGTTGCAGCTGCTATTGAAGCGCGGTCGGAGCATCCTTTAGGCGAGGCCATAACGAAAT
ACGCCAAGGACGCAGGAATTGACGCGCCTGCCGTTAGCGGGTTTAGATCCGTTCCAGGGCGGGGAGCACAGGGAAACATA
GGTGATAAGCGGTACCACATCGGGAGTGAACGCTTCATTGCCGAACTTGGGATTAGCCTTGCGGCAGCCCGAAAAGACAT
TGCAAGGTTGCAGTCGTGTGGCAAAACGGTAATAATTGTGGGAGATGATAAGAGAGTCCTCGGGCTTATTGCGACAGCGG
ATACCTTGCGCGAACACAGCCGCGCGGCAGTCAGTAAACTGAAACAGCTAGGGATAAGGAAAACGGTGATGCTAACCGGG
GACAACGAATCTACGGCAAGCGCTGTTGGTCGCGAGGTAGGGATTGACGAATTTAGAGCGGACTTGTTACCCGAGGGGAA
ACTGGACGTTATCAGAGACCTTTTGGCCAAATATGGTAAAGTGGCGATGGTAGGCGATGGGGTGAACGATGCTCCGGCCA
TGGCGGCGTCGACAGTGGGCATCGCAATGGGCGCGGCAGGAACCGATGCTGCTTTAGAAACGGCCGATATTGCCTTAATG
GCCGATGATCTCTTAAAGTTACCCTATACGGTGAAGCTGAGCCGAAAAGCCGTGAGTATCATTCGGCAAAATATAGCATT
TTCCTTATTATTAAAAGGGATCATCTTGTTGCTGGTAATACCGGGATGGTTGACCATGTGGCTGGCGGTGGCTGGAGATA
CGGGGACATCGTTGTTGGTGACTCTTAACAGCATGAGGTTACTGCGGGCCCGAGACTAA

Protein sequence :
MDKAVTIPDAAFSADIYVRGIDCPDCAARVEQAVKGLPGVINAKVLVRSSKLAFLYDPALIEVEQVVSKVSELGYTTTKA
EGCSNTGALAEGITSTIRIFGLDCGDCAAKLETGLRRIPGVKRAVVNLALSKVEVDHSGPLPEILKTIEAMGYTAKLEDR
RLKSGFDGQNTATSKYALPTVLSGTMVAIGLFFGLLGLPDSIVSAAYLVAILFGGYLPARNGWAIIRSARELDMNVLVVI
AVAGAVAIGRLEEAAAVVFLFSLGNTLQGYTFERTRSSIRALMELAPDEAVVRRDGREEVLSVQDIRIGDVVIVRPGERV
PVDGRILEGTTFVNQAAITGESVPVEKKPGDEVLAGSINGMGALEVEVTRAAQDNTVSRIIRLVEQAQTQRAPSQQTVDR
FARYYTPIVITAAILVAIVPPLGLHQPFNKWLYEALAMLLVACPCALVISTPVAVVAALGNAARNGVLIKGGGYLEEAGT
LSVVAFDKTGTLTVGEPRVTDVVPLTATAQEVIQVAAAIEARSEHPLGEAITKYAKDAGIDAPAVSGFRSVPGRGAQGNI
GDKRYHIGSERFIAELGISLAAARKDIARLQSCGKTVIIVGDDKRVLGLIATADTLREHSRAAVSKLKQLGIRKTVMLTG
DNESTASAVGREVGIDEFRADLLPEGKLDVIRDLLAKYGKVAMVGDGVNDAPAMAASTVGIAMGAAGTDAALETADIALM
ADDLLKLPYTVKLSRKAVSIIRQNIAFSLLLKGIILLLVIPGWLTMWLAVAGDTGTSLLVTLNSMRLLRARD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 5e-147 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-147 46
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-147 46
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 4e-116 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slip_0800 YP_003702145.1 ATPase P BAC0124 Protein 8e-94 44
Slip_0800 YP_003702145.1 ATPase P BAC0298 Protein 1e-111 42
Slip_0800 YP_003702145.1 ATPase P BAC0092 Protein 1e-98 41