Gene Information

Name : Slip_0367 (Slip_0367)
Accession : YP_003701716.1
Strain : Syntrophothermus lipocalidus DSM 12680
Genome accession: NC_014220
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 373996 - 374697 bp
Length : 702 bp
Strand : +
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR011991:IPR011006:IPR016032:IPR001789:IPR 001867; KEGG: sas:SAS1621 alkaline phosphatase synthesis transcriptional regulatory prot

DNA sequence :
GTGAAGGCCAGGATACTGGTAGTTGAAGATGATCATGCTCTCGTGAGTTTGCTAACACATAATTTAGAGCGGGAGGGATA
TGAAACGGGGGTGGCGATGGATGGGGACGAAGCCTGGCGCAAGATCCAGTCAGGCGAGTGGGATGTTATCCTCCTGGACG
TAATGTTGCCTCATCGTGACGGGCTGGAAATATGTCGACAACTGCGGCAGGAAAAAAATTATACTCCGGTTATAATGTTA
ACGGCTCGGGATGACGAGATCGATCGGGTGGTCGGTTTGGAGATAGGGGCCGATGATTACGTTACCAAACCTTTCAGCGT
GCGGGAACTGATGGCCAGAATAAAGGTGATACTGAGGCGCAGAAATCTCGACCTGTATGAGGGCAAACCGGAGATAGAGG
CCGGTCCGATACTCATCCGCCCAGAAAACTACGAAGTGTTCTTAAAGGGGCAAAAGGTAGATCTGACCCGCAAAGAGTTC
GAGCTCCTTACCTTGCTGGTTCAAAACAAAGGAAGGGTTTTGAAAAGAGACTACTTGCTGCAGAGGCTGTGGGACTACGG
TGATACAGTTAAGACTAGGGTTTTGGATGTACACGTAAGCAAGCTGAGAGAGAAACTTGCGAGCTACGGCCTGAAAGGCG
GGGGTATCGAGACGGTGAGGGGGATCGGCTATAAGTTTGAGGAGAAAGGTTATGAAGAATAA

Protein sequence :
MKARILVVEDDHALVSLLTHNLEREGYETGVAMDGDEAWRKIQSGEWDVILLDVMLPHRDGLEICRQLRQEKNYTPVIML
TARDDEIDRVVGLEIGADDYVTKPFSVRELMARIKVILRRRNLDLYEGKPEIEAGPILIRPENYEVFLKGQKVDLTRKEF
ELLTLLVQNKGRVLKRDYLLQRLWDYGDTVKTRVLDVHVSKLREKLASYGLKGGGIETVRGIGYKFEEKGYEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 6e-37 41
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 1e-37 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 5e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 5e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 2e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 3e-55 50
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP001485.1.gene721.p Protein 2e-33 46
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator AE016830.1.gene1681. Protein 2e-49 46
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 1e-45 46
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator HE999704.1.gene1528. Protein 1e-33 45
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP001138.1.gene4273. Protein 1e-29 44
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator BAC0533 Protein 9e-30 44
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002695.1.915041.p Protein 2e-30 44
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP000647.1.gene4257. Protein 9e-30 44
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP000034.1.gene3834. Protein 2e-30 44
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_010079.5776364.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002952.2859858.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_007622.3794948.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_003923.1003417.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_013450.8614146.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002951.3238224.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_007793.3914065.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_002758.1121390.p0 Protein 1e-43 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP001918.1.gene5135. Protein 8e-25 43
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP004022.1.gene3215. Protein 3e-32 42
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_012469.1.7686381. Protein 2e-41 42
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 1e-38 42
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator CP000675.2.gene1535. Protein 5e-36 41
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator AE015929.1.gene1106. Protein 1e-39 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator VFG1390 Protein 8e-34 41
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator VFG1702 Protein 3e-37 41
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator VFG1563 Protein 8e-38 41
Slip_0367 YP_003701716.1 winged helix family two component transcriptional regulator VFG1389 Protein 3e-31 41