Gene Information

Name : Slip_1701 (Slip_1701)
Accession : YP_003703024.1
Strain : Syntrophothermus lipocalidus DSM 12680
Genome accession: NC_014220
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1770920 - 1772665 bp
Length : 1746 bp
Strand : -
Note : COGs: COG0469 pyruvate kinase; InterProIPR015793:IPR015794:IPR008279:IPR015813:IPR 015795:IPR011037:IPR018209:IPR001697; KEGG: swo:Swol_2040 pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SP

DNA sequence :
TTGCGGAAGACCAAAATCATCTGTACCCTGGGACCTTCCACCGATGATTATGAGCGGCTAAGAGCTTTGATCACCAACGG
CATGAACGTGGCCCGTTTGAATTTTTCACACGGCACTTATGATGAGCATGAGCGCCGCATCCGCATGGTGCGTGAGGTGG
CGCGGGAACTGAATGCGGAAGTAGGGTTGATGCTTGATACCAAAGGGCCGGAGATCAGGACCGGGCCCTTGAAAGAAGGT
AAGATAGAGCTGCGTCCTGGTCAAAAGTTCGTTCTCACCAACCGTCCGGTTGAAGGTAACGAAGACGAGGTCCAGATAAG
TTACCATGAGTTACCTTCGCAGGTAAAAGCGGGTGACTGCATATTGATCGCTGACGGCGTCATCCAGCTGTCTGTTTTAG
AGGCGAACGACACCGACATCGTCTGCCAGGTGGTTGCGGGAGGAGTACTCGGTGAAAGGAAAGGCATAAACCTGCCGGGT
GTGAGAACCAACCTGCCTTTTTTGAGCCAGAAAGACATCGAAGACATTAACTTCGGCATCCAGCAGAATATGGATTTCAT
TGCTGCCTCGTTCGTAAGGACGGCCGATGATGTTTTGGATATCAGACGCATATTAGAGGAAAAGGGAGCCGACATCGATA
TAATCGCTAAGATTGAGAGCCAGGAGGGGCTGGACAACCTGGATGACATAATAAAGGTTGCTGATGGCGTCATGGTCGCC
CGGGGAGACCTGGGGGTTGAAATACCTACCGAAGAAGTACCTCTGGTGCAAAAGGTTATAATCGAGAAATGCCGGGCTCA
GGGTAAGCCGGTGATAATTGCCACCCAGATGCTCGAATCGATGGTAAACGTGCCGCGCCCCACCCGGGCCGAAGCGTCAG
ACGTGGCTAATGCCATATTTGAGGGGGCAGACGCCATTATGCTGTCGGCAGAGACCGCAGCCGGTAAATATCCGGTAGTT
GCGGTGGAAACCATGGCGCGAATAGCCCGGCGGACGGAGATGGCTTTGCCCTATGAGAACATGCTGGCGGCAAGACGATT
CGAAGGCAGGCGTACCGTGACCGATGCCATCAGTTATGCCACCTGTGCTACCGCTACCGACCTGGGGGCCTCGGCCATTG
TTACTGCTACAAAATCGGGCCATACGGCGAGAATGGTGGCCAAGTACCGTCCCCGGGCTCCGATCGTGGCTACTACGCCT
TCACCCGAAGTGGTACGCAAGCTAACTTTGGTATGGGGGGTATACGCGCTCACGGTCCCGGAAACCCACGGAACTGACCA
GATGATAGAAACAGCCCTGGATGCCGCAGTCAGGCGAGGGCTAATCTCCCCCGGTGACCTGGTAGTCATAACCGCAGGTA
CTCCTGGAATCCCTGGGACTACCAATCTACTGAGAGTTCAAGTAGTAGGCAAGGTGCTGGTTAAGGGAACGGGTATAGGT
AGCCGGGCCGTTACCAGTAAGGCGCGGGTGATACTGGATCCGGGCAAACCGGGCTCGTTTGCTCCGGGAGATATAGTGGT
GGCAGTCGGAACAGACAAGGACTATATGCCGTTGTTGGAAAAGGCCGGGGGGATTATCACGGAACAGGGAGGCCTGACTT
CTCATGCAGCCATAGTAGGTATTAACTTGGATATTCCTGTCATCGTTGGAGCCGCCGAGGCAACCCGTGTCATCCAAGAC
GGAGAAACCATAACCATGGATACGGCTAGGGGACAAATCTACCGCGGCCAAGCCCAAGTGCGGTAA

Protein sequence :
MRKTKIICTLGPSTDDYERLRALITNGMNVARLNFSHGTYDEHERRIRMVREVARELNAEVGLMLDTKGPEIRTGPLKEG
KIELRPGQKFVLTNRPVEGNEDEVQISYHELPSQVKAGDCILIADGVIQLSVLEANDTDIVCQVVAGGVLGERKGINLPG
VRTNLPFLSQKDIEDINFGIQQNMDFIAASFVRTADDVLDIRRILEEKGADIDIIAKIESQEGLDNLDDIIKVADGVMVA
RGDLGVEIPTEEVPLVQKVIIEKCRAQGKPVIIATQMLESMVNVPRPTRAEASDVANAIFEGADAIMLSAETAAGKYPVV
AVETMARIARRTEMALPYENMLAARRFEGRRTVTDAISYATCATATDLGASAIVTATKSGHTARMVAKYRPRAPIVATTP
SPEVVRKLTLVWGVYALTVPETHGTDQMIETALDAAVRRGLISPGDLVVITAGTPGIPGTTNLLRVQVVGKVLVKGTGIG
SRAVTSKARVILDPGKPGSFAPGDIVVAVGTDKDYMPLLEKAGGIITEQGGLTSHAAIVGINLDIPVIVGAAEATRVIQD
GETITMDTARGQIYRGQAQVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-95 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-95 48
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-95 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-95 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slip_1701 YP_003703024.1 pyruvate kinase VFG0479 Protein 4e-96 48