Gene Information

Name : Slip_1127 (Slip_1127)
Accession : YP_003702469.1
Strain : Syntrophothermus lipocalidus DSM 12680
Genome accession: NC_014220
Putative virulence/resistance : Unknown
Product : adenine-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 1169248 - 1170819 bp
Length : 1572 bp
Strand : -
Note : COGs: COG0286 type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR002296; KEGG: dol:Dole_2236 N-6 DNA methylase; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: A1HQI1 N-6 D

DNA sequence :
ATGCCGTCAATCAACAATGAAATAGAAAAGAAGCTGTGGAACGCGGCAGACCAATTAAGAGCTAACTCGAAATTAAAAGC
TTCAGAATACTCGGTTCCCGTGCTTGGGCTGATATTCCTGCGCTTTGCCGATCACAAGTTCAGTATGGCCGAAAAGGAGC
TGGCTAAAAAGGCTAAGGCAGGTTCAAGGCGTGTTATTGGCAAAGCTGACTATCAAGCCAGGGGGGTTATGTACCTTCCA
GAACAGGCGAGATATTCTTACCTCCTGAAGCTGCCGGAAGGGGAGAATATCGGGAAGGCTGTGAACGAAGCCATGAAAGC
CATCGAAGCCGAGAACGAAGACCTTAAGGATGTCCTTCCCAAAACCTATACCCGGCTGGACAACGATACACTGATAGCTC
TACTAAAAACATTCTCCGAAATCCCGATGGACGTCGAAGGGGACGTTTTTGGCAACGTATATGAATACTTTCTCGGCGAG
TTCGCACGTTCAGAAGGGCAGCGGGGCGGGGAATTTTACACGCCCACTTCGCTGGTAAAGCTAATTGTCGAGGTCATCGA
GCCATACCGAGGACGCATCCTGGACCCGGCCTGCGGGTCAGGCGGCATGTTTGTCCAGTCGGCCCGGTTTGTCCAGAATC
ACAAGAAAAACCCCAGCAGTGAGATATCCATCTACGGGCAGGAGAAAGTGGCCGAAACAGTCAGACTGTGCAAGATGAAC
CTCGCGGTCCACGGGCTTTCGGGGGACATCCGTCAGGCCAACACCTATTACGAGAATGTACATAACTGCATAGGCCGGTT
CGATTTTGTCATGGCTAATCCCCCCTTCAACGTGGACGGGGTGGACAAAGAGAAGATCAAAGACGACCCGCGTTATCCTT
TTGGGCTTCCCACTGTCGATAACGCCAACTACATCTGGATCCAGGAGTTTTACAGCGCTTTAAACGATACTGGACGGGCG
GGCTTCGTCATGGCCAACTCTGCCAGCGATGCCAGGGGTTCTGAACTCGAGATAAGAAAAAAGCTCATCCAGGACCGGGT
TGTGGATGTGATGATCACCATCGGGCCTAACTTCTTCTATACCGTTACTCTACCATGCACCCTCTGGTTCTTCGACAAGG
GTAAACGGCAGACTGAGCGGGGTAATAAAGTGCTGTTCATCGATGCGAGGAACATCTACCGCCAGGTAGACCGGGCCCAC
CGCGAGTTTACCCCGGAACAGATTGAGTTTATCGCCAATATCGTACGCTTGTACCGGGGCGAGCCGGTGGAGACCGTAAA
TGGGTCGGATGAAATGCTCGAGGATAAGTTTCCGGAAGGCAAATATGTGGATGTGCCTGGCCTGTGCAAGGTAGCGACTA
TAGAGGAAATCGAAGCCCAGGGCTGGAGCCTCAACCCCGGCAGGTATGTTGGTGTGGCTCAGAAGGAAGAGGAAGACTAT
GATTTCACGGAAAGGCTGCAAGAGCTGAACGAAGAGTTGGAGCAGCTCAACGCCGAGGCAGCGGAGCTGGAGGAAAGGAT
AAGGGAGAATGTGGGAAAGTTATTGGAGGGTTTTGATGAAAAGCTCGACTAA

Protein sequence :
MPSINNEIEKKLWNAADQLRANSKLKASEYSVPVLGLIFLRFADHKFSMAEKELAKKAKAGSRRVIGKADYQARGVMYLP
EQARYSYLLKLPEGENIGKAVNEAMKAIEAENEDLKDVLPKTYTRLDNDTLIALLKTFSEIPMDVEGDVFGNVYEYFLGE
FARSEGQRGGEFYTPTSLVKLIVEVIEPYRGRILDPACGSGGMFVQSARFVQNHKKNPSSEISIYGQEKVAETVRLCKMN
LAVHGLSGDIRQANTYYENVHNCIGRFDFVMANPPFNVDGVDKEKIKDDPRYPFGLPTVDNANYIWIQEFYSALNDTGRA
GFVMANSASDARGSELEIRKKLIQDRVVDVMITIGPNFFYTVTLPCTLWFFDKGKRQTERGNKVLFIDARNIYRQVDRAH
REFTPEQIEFIANIVRLYRGEPVETVNGSDEMLEDKFPEGKYVDVPGLCKVATIEEIEAQGWSLNPGRYVGVAQKEEEDY
DFTERLQELNEELEQLNAEAAELEERIRENVGKLLEGFDEKLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 5e-84 43
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 5e-85 43
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-83 42