Gene Information

Name : Arch_0899 (Arch_0899)
Accession : YP_003697243.1
Strain : Arcanobacterium haemolyticum DSM 20595
Genome accession: NC_014218
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1022866 - 1024284 bp
Length : 1419 bp
Strand : -
Note : COGs: COG0469 pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PRIAM: pyruvate kinase; SPTR: D0WMQ1 pyruvate kin

DNA sequence :
ATGCGTAGAGCGAAAATTGTATGTACTTTAGGTCCTGCGGTTAATTCCAAGGATCAGATTCTTGAATTGGTGAAGGCTGG
CATGAACGTGGCCCGCATCAATGCCTCTCACGGCTCGCATGAAGAGCACGAAGAGCGCATCGATTGGGTTCGTCAAGCCT
CCGAAGAACTCCGGAAGCCAGTGGCTGTTCTTGTGGATCTTCAAGGTCCAAAGATTCGCCTTGGGCGTTTTGCAGAAGGC
CCCGTGCTTCTGAACACAGGTGATATTTTCACGATCACCACTGATGATATTCAGGGCGATAAGGATCGCGTGTCCACCAC
ATTTAAGGGTCTGCCAGGGGATTGTTCCGAAGGTGATTTGATTCTTATTGACGATGGCAAGGTGCAGGTACGTGTACTTT
CTGTGGAAGGAAATGACGTCCGTACCCAGGTTCTTGTTGGCGGAACTGTGTCCAACAACAAGGGCGTGAACCTGCCAGGT
GTGGCTGTTTCTGTTCCAGCTCTGTCCGAAAAGGATAAGGAAGATCTGGAATGGGGCCTCGAATACGGTGCTGATTTGAT
CGCGCTGTCATTCGTCCGTTCGCCAAAGGATATCGATGACGTCCACGAAGTTATGGATCGTGTTGGCCGCCGTATCCCTG
TTATTGCGAAGATTGAAAAGCCACAGGCTGTAAATGTTCTTGAAGATATTGTTCGAGCATTCGATGGTTTGATGGTGGCG
CGTGGTGATTTGGGTGTGGAACTTCCACTCCAGCAGGTGCCGATCGTGCAGAAGCATGCAATTTCCATTGCACGCCGTAA
TGCGAAGCCAGTTATCGTGGCAACGCAGGTTCTGGAATCCATGATCTCGGCTCCAACCCCAACTCGTGCAGAAACGTCTG
ACTGTGCTAATGCGATTCTTGATGGTGCCGATGCGGTTATGCTTTCTGGCGAAACCTCGGTGGGTAAGTACCCGATCATT
TGTGTTCAAACAATGGCGTCGATCATTGAATACACGGAAGAACACGGTATTGAATCTATCCCGCGTATCGGCAACCTGCA
CCGTACTCGCAATGGCGTGATTACCCGTTCTGCTATGGATATTGGTGAAGCAATCGGCGTGAAGTTCATTGCCGTCTTTA
CTTCGTCTGGCCAGACTGCCCGCCGTATGTCTCGCCTCCGTGGCCGTATTCCACTTGTTGTCTTTACAGATAACGAACAG
GTACGCCGCCAGCTGGCACTCTCGTGGGGTCTTGACACCCTCACCTTGGCACCAGTCTCATCTACCGATGAAATGGTTGA
CCAGGTTGATGATGTGTTGCGTAAGGAAGGTCTTGCCGTGGATGGCGATCGCGTTGTGATCGTTTCCGGTATGCCACCAG
GCGTTGTTGGTTCCACTAACACGATTCGCATTCACAAGATGGGTGAGACACGCCGTTGA

Protein sequence :
MRRAKIVCTLGPAVNSKDQILELVKAGMNVARINASHGSHEEHEERIDWVRQASEELRKPVAVLVDLQGPKIRLGRFAEG
PVLLNTGDIFTITTDDIQGDKDRVSTTFKGLPGDCSEGDLILIDDGKVQVRVLSVEGNDVRTQVLVGGTVSNNKGVNLPG
VAVSVPALSEKDKEDLEWGLEYGADLIALSFVRSPKDIDDVHEVMDRVGRRIPVIAKIEKPQAVNVLEDIVRAFDGLMVA
RGDLGVELPLQQVPIVQKHAISIARRNAKPVIVATQVLESMISAPTPTRAETSDCANAILDGADAVMLSGETSVGKYPII
CVQTMASIIEYTEEHGIESIPRIGNLHRTRNGVITRSAMDIGEAIGVKFIAVFTSSGQTARRMSRLRGRIPLVVFTDNEQ
VRRQLALSWGLDTLTLAPVSSTDEMVDQVDDVLRKEGLAVDGDRVVIVSGMPPGVVGSTNTIRIHKMGETRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-68 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-68 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-68 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Arch_0899 YP_003697243.1 pyruvate kinase VFG0479 Protein 5e-69 42