Gene Information

Name : Snov_1390 (Snov_1390)
Accession : YP_003693319.1
Strain : Starkeya novella DSM 506
Genome accession: NC_014217
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1454178 - 1455890 bp
Length : 1713 bp
Strand : +
Note : TIGRFAM: urease subunit alpha; KEGG: rpe:RPE_3732 urease subunit alpha; PFAM: amidohydrolase; urease alpha-subunit domain protein

DNA sequence :
ATGTCCATCAAGATTTCCCGCGCCACCTATGCCGAGATGTTCGGGCCGACCACCGGCGACCGCGTGCGGCTGGCAGATAC
GTCGCTCATCATCGAGGTGGAGAAGGACCTCACCGTCTATGGCGAGGAGGTGAAGTTCGGCGGCGGCAAGACCATCCGCG
ACGGCATGGGCCAGTCGCAGGTGATGCGCGCCGAGGGCGCGGTCGACACCGTGATCACCAATGCGCTGATCCTCGACCAC
TGGGGGATCGTCAAGGCCGACATCGGCATTCGCGACGGGCGCATCCACGGCATCGGCAAGGCCGGCAATCCCGATATCCA
GCCAGGTGTCGACATTATCATCGGCGCCTCGACCGAGATCATCGCCGGCGAGGGCAAGATTATTACGGCTGGAGGCTTCG
ACAGTCACATTCATTTCATCTGCCCGCAGCAGATCGAGCACGCGCTGATGAGCGGTGTCACCACCATGCTCGGCGGCGGC
ACCGGCCCCGCCGCCGGCACCAACGCCACGACCTGCACGCCCGGGCCATGGCACATCGAGATGATGCTGCGCGCCTTCGA
CTCTTTCCCCGTCAATCTTGCTTTGTCCGGCAAGGGCAACGCCTCGCTGCCCGGCCCGCTGATCGAGATGATCGAGGCGG
GGGCCTGTTCGCTCAAGCTGCATGAGGACTGGGGCACGACGCCGGCGGCGATCGACAACTGCCTGTCGGTGGCCGACGAG
TACGACATCCAGGTGATGATCCACACCGACACGCTCAACGAGAGCGGCTTCGTCGAGGACACCATCGCCGCCTTCAAGGG
ACGCACCATCCACGCCTTCCACACGGAAGGGGCGGGCGGCGGTCACGCGCCGGACATCATGAAGGTGGCTGGCCTGCCCA
ACGTGCTGCCGTCCTCGACCAATCCGACGCGGCCCTTCACCATCAACACGCTCGACGAGCATCTCGACATGCTCATGGTG
TGTCACCACCTCGACCCGCTGATCGCCGAGGACCTCGCCTTCGCCGAGAGCCGCATCCGCAAGGAGACCATCGCAGCCGA
GGACATCCTGCATGACCTCGGCGCCATCTCGATGATGAGCTCGGACAGCCAGGCCATGGGCCGGCTCGGCGAAGTCATCA
CCCGCACCTGGCAGACCGCGCACAAGATGAAGCTGCAGCGCGGCCTGCTGCCGGGGGACAGCGAACGCAACGACAATGCC
CGCGCCAAGCGCTACATCGCGAAATACACGATCAACCCGGCCATCGCGCACGGCGTCTCCCGCCATATCGGCTCGGTGGA
GACGGGAAAGCTCGCCGACCTCGTCGTCTGGTCGCCGGCCTTCTTCGGTACCAAGCCGGACATGGTGATCAAGGGCGGTA
CCATCGTCGCGGCGCAGATGGGCGATCCCAATGCCTCCATCCCGACGCCGCAGCCGGTGCATTACCGGCAGATGTGGGGC
GCCTATGGCAAGGCCCGCACCGCGACCAGCCTGACCTTCGTCTCGCAGGCGGCGATCGACCTCAATGTCGGCCACAAGCT
TGGGCTGGAGAAGCGCACCGTGGCGGTGGAGAATGTGCGCGGCGGCATCTCCAAGGCATCGATGGTTCACAACAGCGCGA
CGCCGCATCTGGAGATCGACCCGGAAACCTATGAGGTACGGGCGGATGGCGAGCTCCTGACCTGCGCCCCCGCCACCGAG
CTGCCCATGGCGCAGCGCTACTTCCTGTTCTAA

Protein sequence :
MSIKISRATYAEMFGPTTGDRVRLADTSLIIEVEKDLTVYGEEVKFGGGKTIRDGMGQSQVMRAEGAVDTVITNALILDH
WGIVKADIGIRDGRIHGIGKAGNPDIQPGVDIIIGASTEIIAGEGKIITAGGFDSHIHFICPQQIEHALMSGVTTMLGGG
TGPAAGTNATTCTPGPWHIEMMLRAFDSFPVNLALSGKGNASLPGPLIEMIEAGACSLKLHEDWGTTPAAIDNCLSVADE
YDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMKVAGLPNVLPSSTNPTRPFTINTLDEHLDMLMV
CHHLDPLIAEDLAFAESRIRKETIAAEDILHDLGAISMMSSDSQAMGRLGEVITRTWQTAHKMKLQRGLLPGDSERNDNA
RAKRYIAKYTINPAIAHGVSRHIGSVETGKLADLVVWSPAFFGTKPDMVIKGGTIVAAQMGDPNASIPTPQPVHYRQMWG
AYGKARTATSLTFVSQAAIDLNVGHKLGLEKRTVAVENVRGGISKASMVHNSATPHLEIDPETYEVRADGELLTCAPATE
LPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 7e-166 69
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 7e-166 69
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-156 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-157 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 9e-157 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-157 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snov_1390 YP_003693319.1 urease subunit alpha VFG0270 Protein 2e-145 63