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Name : drrA (PFREUD_21560) Accession : YP_003689072.1 Strain : Propionibacterium freudenreichii CIRM-BIA1 Genome accession: NC_014215 Putative virulence/resistance : Unknown Product : Daunorubicin resistance ATP-binding protein DrrA Function : - COG functional category : V : Defense mechanisms COG ID : COG1131 EC number : - Position : 2325308 - 2326378 bp Length : 1071 bp Strand : + Note : DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC DNA sequence : ATGACTGAAACACTCGCCGTCGAGGCGCACGGACTGGTCAAGCAGTTCGGCTCGAACCGCGCCGTCGACGGAGTCGACCT GGCCATCGACCAGGGCGCCATCTACGGCGTGCTCGGCCCCAACGGAGCCGGCAAGACCACCACCATCTCAATGCTCGCCA CCCTGCTGCGTCCCGACGCCGGCAGCGCCACGATCTTCGGCCACGACGTGGAACGCCAGGCCGGAATCGTGCGCCAGCTG ATCGGCGTCACCGGCCAGTACGCGTCGGTGGACGAGACCCTCACCGCCACCGAGAACCTGATGATCTTCGGGCGGCTGTT GGGCCTGTCACGGCGCCAGGCCCGCGCCAAGGCCACCGAACTGCTCGAACAATTCGGCCTCACCGACGCCGCCGCGCGTC CGCTCAAGAACTTCTCGGGAGGCATGCGCCGACGCCTCGACCTGGCATCGTCGCTGATCGCCCAGCCGCCGCTGATCTTC CTCGACGAACCCACCACCGGGCTCGACCCGCGCACCCGCGGGCAGATGTGGGACACCATCCGCTCGCTGGTGGCCGGCGG CTCCACCGTGCTGCTGACCACCCAATACCTCGACGAGGCCGACCAACTGGCCGACCGCGTCGCCGTGATCGATCGTGGCC GGGTGGTGGCCGAGGGCACCCCCGACGACCTCAAGCGCTCGGTGGGTTCCGCCTCGCTGATCATCACCCTGCGCGAGCCG GCCGACGCCGTCCCCACGATGGCGGTGATCGAGCGCGTGCTCGGGGTGGCCGCCTCGCGCAGCCCCGAATCGGGCCGCCT CACCATGCCGCTGACCGATCCCGACCACGTGACCGACCTGCTCAACGCACTGCGCGCCGACAGCATCGGCCTGGTCGAGC TGAGCGTGCAGAAGCCCACCCTTGACGAGGTCTTCCTCACCCTGACCGGCCACGACACCCACAGCGCCGATCCCAGCACC GGCGCTTCCGACAGCGCCGATCCCACCGAATCCCCACGCACCGAATCCCCACGCACCGACGCCTCCGCGACGTCCACCAA CTCTTCCGCCCGGGAGGCGAATGCAGCATGA Protein sequence : MTETLAVEAHGLVKQFGSNRAVDGVDLAIDQGAIYGVLGPNGAGKTTTISMLATLLRPDAGSATIFGHDVERQAGIVRQL IGVTGQYASVDETLTATENLMIFGRLLGLSRRQARAKATELLEQFGLTDAAARPLKNFSGGMRRRLDLASSLIAQPPLIF LDEPTTGLDPRTRGQMWDTIRSLVAGGSTVLLTTQYLDEADQLADRVAVIDRGRVVAEGTPDDLKRSVGSASLIITLREP ADAVPTMAVIERVLGVAASRSPESGRLTMPLTDPDHVTDLLNALRADSIGLVELSVQKPTLDEVFLTLTGHDTHSADPST GASDSADPTESPRTESPRTDASATSTNSSAREANAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| CDCE8392_1976 | YP_005134507.1 | methionine import ATP-binding protein | Not tested | Not named | Protein | 3e-61 | 47 |
| CDC7B_2054 | YP_005163495.1 | methionine import ATP-binding protein | Not tested | Not named | Protein | 3e-61 | 47 |
