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Name : clpB (PFREUD_19250) Accession : YP_003688837.1 Strain : Propionibacterium freudenreichii CIRM-BIA1 Genome accession: NC_014215 Putative virulence/resistance : Virulence Product : ATP-dependent Clp protease B1 Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 2072215 - 2074791 bp Length : 2577 bp Strand : - Note : The protein has been identified by proteomics as a 95 kDa protein induced by various stresses.several 90 to 100 kda clp chaperones are expressed as disctinct heat shock proteins DNA sequence : ATGAGCCGCGACGCCGTCACGGCTGCGGTCAGGCTGGCCCTCACCAAGGGCAATCCGACCGCCGAGCCCGTGCACCTGCT GCACGCGATGCTCATGGTGCCCGAGAGCTCTGTGGCGCCGCTGCTGAAGGCAGTGGGTGCCGATGCCGCACGCGTCGACG GCGCCGCCTCGGCAGCCATCGACAAGCTGCCGAGCAGCTCGGGCTCCTCGGTGGCACAACCACAACTGTCCGGCGCGCTG GCCAGGGTGCTGGCCGATGCCGAGACGCGTGCCGACAAGCTGGGTGACCAGTTCGTCAGCACCGAACACCTGCTCATCGC CCTGGCCGAGGTCGATTCGGACGCGAAGAACATCCTCGCGTCGAACGGCGTCACCACGGCGGCCCTGGAGAAGGCATTCA ACGACTCGCGTGGTGACAAGCGCATCACCAGCGCCGAATCGGAGGGCGGGGAATCCGCACTCGACAAGTACTCGATCGAC CTCACCCAGCGTGCCAAGGACGGCAAGCTCGATCCGGTGATCGGCCGCGACTCCGAGATCCGTCGCGTGGCGCAGGTGCT GAGCCGTCGCACCAAGAACAACCCGGTGCTCATCGGCGAGGCTGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTGGCCC AGCGCATCGTCAAGGGCGATGTGCCCGATTCGCTGAAGGGACGCCGACTGGTGTCGCTCGACCTGGCGTCGATGGTCGCC GGGGCAAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGGCCGTGCTCAACGAGATCAAGAGCGCCGAGGGCCAGATCAT CACCTTCATCGACGAGCTGCACACCGTGGTGGGTGCCGGCGCGTCCGAGGGTTCGATGGACGCCTCGAACATGTTGAAGC CGCTGCTGGCGCGCGGTGAGTTGCGCCTGATCGGCGCGACCACGCTGGACGAATACCGCGAGCACATCGAGAAGGACCCG GCCCTGGAGCGTCGTTTCCAGCAGGTCTATGTCGGTGAGCCGTCCGTGGAGGACACGGTGGCCATCCTGCGTGGGCTGCG CGAGCGCTATGAGGCCCACCACAAGGTGCGCATCACCGACTCCGCGCTGGTTGCCGCCGCACAGCTGTCACATCGCTACA TCACCGGTCGACAGCTGCCTGACAAGGCCATTGACCTGGTGGACGAGGCCGCCAGCCGCCTGCGCATGGAGATCGACTCG AGCCCCGAGGAGATCGACACGCTGCGCCGTCAGGTGGATCGCCTGACCATGGAGCAGTTCGCCGTCGAGAAGGAGGAGGA CCCCGGTTCCAAGGCACGCCTGGCCCGGATCAACTCCGACCTCGCCGACGCCAAGGAGCAGCTGCGGGGCCTCGAGGCCC GGTGGGCCGCCGAGAAGGAGGGCCTCAACAAGGTCGGCGAGCTGAAGACCCGCATCGACGCGCTGCGCACCGAGGCCGAC AAGCACACCCGTGACGGCGACCTGGCCAAGGCAAGCGAGATCCTCTACGGCGAGATCCCCGAGCTCAACAAGCAGCTCGA CGAGGCATCTGCGGCCGAGGAGGATTCGCAGGGCAAGTCGATGGTCTCCGAGGAGGTCACCAGCGACGACATCGCCGAGG TCGTGTCGGCATGGACCGGCGTGCCCGTGGGCAAGATGCTCGAGGGCGAGAGCGAGAAGCTGCTCGACATGGAGAACCGC ATCGGCAAGCGGTTGGTGGGCCAGCAGGCCGCCGTCAAGGCGGTCTCTGATGCGGTGCGTCGTTCGCGCGCCGGCATCTC CGACCCGAATCGTCCGACCGGTTCGTTCATGTTCCTGGGCCCCACCGGCGTCGGCAAGACCGAGCTGGCCAAGGCCCTGG CCGACTTCCTGTTCGACGACGAGACCGCGATGGTGCGCATCGACATGAGCGAGTACATGGAGAAGCACTCCGTCTCGCGC CTGGTCGGTGCCCCTCCGGGCTATGTCGGCTACGAGGAGGGTGGCCAGCTGACCGAGGCCGTGCGGCGTCGTCCGTACTC GGTGGTGCTGCTCGACGAGATCGAGAAGGCCCACCCCGATGTGTTCAACATCCTGTTGCAGGTGCTTGACGATGGTCGCC TGACCGACGGCCAGGGACGCACGGTGGATTTCCGCAATGTGATCCTCATCATGACCAGCAACCTCGGCTCGCAGTTCATG GCCGATCCGAGCATGTCGCCCGAGGAGCGTCGCAACCAGGTGATGGCCGTGGTCAAGGACCACTTCCGTCCCGAGTTCCT CAACCGGCTCGATGAGATCGTGCTGTTCGACGAGCTGAGTCGCGAGGACCTCGACAAGATCGTCGACATCAGCCTGGACA AGCTCAATCGTCGCCTGGCGGAGCGTCGCATCAGCATTGACGTGTCGGCTGCCGCGCGCGAATGGCTCGCCCGCACCGGC TATGACCCGGTGTACGGCGCCCGTCCGTTGCGTCGGTTGATCCAGACCACGGTGGAGGACCAGCTGGCCCGCGCCATGCT GGCCGGCACCATCAGTGACGACCAGAAGGTGAGCGTTGACATGAACCAGGCCGGTGACGGCGTGGACGTGAAGGGCGAGG CCCCTGTGTCTGCGTGA Protein sequence : MSRDAVTAAVRLALTKGNPTAEPVHLLHAMLMVPESSVAPLLKAVGADAARVDGAASAAIDKLPSSSGSSVAQPQLSGAL ARVLADAETRADKLGDQFVSTEHLLIALAEVDSDAKNILASNGVTTAALEKAFNDSRGDKRITSAESEGGESALDKYSID LTQRAKDGKLDPVIGRDSEIRRVAQVLSRRTKNNPVLIGEAGVGKTAVVEGLAQRIVKGDVPDSLKGRRLVSLDLASMVA GAKYRGEFEERLKAVLNEIKSAEGQIITFIDELHTVVGAGASEGSMDASNMLKPLLARGELRLIGATTLDEYREHIEKDP ALERRFQQVYVGEPSVEDTVAILRGLRERYEAHHKVRITDSALVAAAQLSHRYITGRQLPDKAIDLVDEAASRLRMEIDS SPEEIDTLRRQVDRLTMEQFAVEKEEDPGSKARLARINSDLADAKEQLRGLEARWAAEKEGLNKVGELKTRIDALRTEAD KHTRDGDLAKASEILYGEIPELNKQLDEASAAEEDSQGKSMVSEEVTSDDIAEVVSAWTGVPVGKMLEGESEKLLDMENR IGKRLVGQQAAVKAVSDAVRRSRAGISDPNRPTGSFMFLGPTGVGKTELAKALADFLFDDETAMVRIDMSEYMEKHSVSR LVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNVILIMTSNLGSQFM ADPSMSPEERRNQVMAVVKDHFRPEFLNRLDEIVLFDELSREDLDKIVDISLDKLNRRLAERRISIDVSAAAREWLARTG YDPVYGARPLRRLIQTTVEDQLARAMLAGTISDDQKVSVDMNQAGDGVDVKGEAPVSA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 2e-158 | 50 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 7e-114 | 41 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 1e-113 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_003688837.1 | ATP-dependent Clp protease B1 | VFG0079 | Protein | 8e-162 | 47 |
| clpB | YP_003688837.1 | ATP-dependent Clp protease B1 | VFG2084 | Protein | 7e-116 | 42 |
