Gene Information

Name : tpx (PFREUD_01430)
Accession : YP_003687112.1
Strain : Propionibacterium freudenreichii CIRM-BIA1
Genome accession: NC_014215
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 181865 - 182362 bp
Length : 498 bp
Strand : +
Note : peroxydase. Has antioxidant activity. Could remove peroxides or H(2)O(2)

DNA sequence : 
ATGTCAACGACTGCATTCCAAGGAACCCCCGTCCACACCGTCGGCGAACTGCCGGCCGTCGGAAGCCAGGCGCCCGACTT
CGAACTGGTGGGCAAGGACCTGTCCACCATCACCCTGAAGTCCCTGCGTGGACGCCGCGTCGTGCTGAACATCTTCCCGA
GCCTCGACACGGGCGTGTGCGCCACCAGCGTGCGCACCTTCAACAAGCTGGCCGCCGGGCTCGACAACACCACCGTGCTG
GCCGTGTCGAAGGACCTGCCCTTCGCCGCCGAGCGCTTCTGCGTCGCCGAGGGCATTGAGAACGTGGTGCCCGCCTCCGC
GTTCCGCAAGCATTCCTTCAGCAACTACGGCGTGCTGATGACCGACGGCCCGCTGGCCGGACTGCTCGCGCGCAGCGTCG
TGGTGATCGATGAGAACGGCACGGTGGTCTACAACCAGCTCGTCCCCGAGATCGGCAATGAGCCCGACTACGACGACGCG
GTGGCCGCACTGAAGTAG

Protein sequence : 
MSTTAFQGTPVHTVGELPAVGSQAPDFELVGKDLSTITLKSLRGRRVVLNIFPSLDTGVCATSVRTFNKLAAGLDNTTVL
AVSKDLPFAAERFCVAEGIENVVPASAFRKHSFSNYGVLMTDGPLAGLLARSVVVIDENGTVVYNQLVPEIGNEPDYDDA
VAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-31 43
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 9e-32 43
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-31 43
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 6e-32 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_003687112.1 thiol peroxidase VFG0087 Protein 3e-32 43